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Who should worry about H5N1? 591 implied HN points • 04 Feb 23 There is concern about the H5N1 avian influenza outbreak due to recent mammal-to-mammal transmission. Authorities need to take aggressive action to prevent the potential spread of H5N1 to humans. Vaccine production for H5N1 needs to be ramped up, focusing on non-egg based platforms and global surveillance.