The hottest Substack posts of The GIZN Journal of Medicine

And their main takeaways

What causes a false positive HIV test?

2 HN points • 03 Jan 24
  1. HIV screening tests can detect HIV markers early after infection.
  2. False positive HIV test results can be caused by factors like other infections or diseases.
  3. Broad-spectrum antibodies from B-lymphocyte activation can lead to unpredictable false positive reactions in HIV tests.

Roundup, week 5 2024

0 implied HN points • 04 Feb 24
  1. A meta-analysis looked at COVID-19 case fatality rates across continents, with the Beta variant showing the highest rate.
  2. Research discusses the impact of AI on biological threat landscapes, focusing on risk analysis.
  3. China reported the first case of a woman's death from H3N2-H10N5 flu coinfection, with human-to-human transmission appearing unlikely.

Roundup, week 4 2024

0 implied HN points • 28 Jan 24
  1. Review on solid organ transplant for HIV patients, from HIV+ to HIV- recipients, and vice versa.
  2. Reminder on the importance of clinical trials to validate hypotheses, like BCG vaccination for COVID-19 protection.
  3. Insightful review on the virology of SARS-CoV-2 from Nature Reviews Microbiology.

Roundup, week 2 2024

0 implied HN points • 14 Jan 24
  1. Study shows potential treatment simplification for Mycobacterium avium pulmonary disease using selected oral betalactam pairs
  2. Study demonstrates safety of MVA-BN vaccine in preventing mpox with low severe adverse events frequency
  3. Insights on using artificial intelligence for developing new antibiotics in the future from a Nature publication

Roundup, week 1 2024

0 implied HN points • 07 Jan 24
  1. Neutralizing antibodies may play a role in the clearance of HCV infection, which could impact vaccine development.
  2. Multiplex molecular diagnostic testing in children with acute gastroenteritis can detect more pathogens and reduce return visits to the emergency department.
  3. Long-term use of glucocorticoids may pose risks for opportunistic infections, regardless of dosage, highlighting the importance of personalized risk assessment.
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Roundup, week 3 2024

0 implied HN points • 21 Jan 24
  1. Cranberry juice may not be effective in treating UTIs.
  2. Vaccines for HIV that stimulate CD8+ T cells have faced challenges.
  3. Intestinal microbiota can influence innate immunity in the body.

Roundup, week 5 2024

0 implied HN points • 11 Feb 24
🏥 Health & Wellness COVID-19 Vaccination Therapy Immunity
  1. Receiving the COVID-19 vaccine during pregnancy does not pose risks to newborns and may offer protection against severe complications.
  2. Paxlovid has shown effectiveness in treating mild to moderate COVID-19 cases during the Omicron epidemic.
  3. After chimeric antigen receptor T-cell therapy, a study found a 27% incidence of CMV reactivation, but no patients developed CMV end-organ disease.