The hottest Immunity Substack posts right now

And their main takeaways
Category
Top Health & Wellness Topics
Ground Truths β€’ 14434 implied HN points β€’ 08 Sep 23
  1. First human data for the new XBB.1.5 booster vaccine show good levels of neutralizing antibodies against BA.2.86 and other variants.
  2. Multiple lab studies have characterized the immune response to the BA.2.86 variant.
  3. Wastewater data and hospitalizations suggest a new wave of COVID-19 cases, highlighting the need for booster shots to provide enhanced protection against severe COVID and Long Covid.
The FLCCC Alliance Community β€’ 1316 implied HN points β€’ 11 Feb 24
  1. Dr. Pierre Kory emphasizes the need for a better healthcare system that puts patients before profits, focuses on robust scientific debate, and empowers patients to take control of their own healthcare.
  2. The FLCCC is conducting an observational cancer study in collaboration with five U.S. clinics to track patient responses to various adjunct cancer therapies using repurposed drugs.
  3. Dr. Pierre Kory presents evidence suggesting clinically significant shedding of spike proteins from vaccinated individuals, which he believes should be a focal point in discussions about mRNA vaccine boosters.
An Insult to Intuition β€’ 1434 implied HN points β€’ 25 Jan 24
  1. Vaccinated individuals may be more susceptible to infection than unvaccinated individuals, as shown in UKHSA data
  2. Receiving mRNA vaccines may lead to higher IgG4 antibody concentrations, which could impact immune responses
  3. Vaccination might not prevent 'Long Covid' according to studies, and there could be a risk of more severe disease after vaccination
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COVID Reason β€’ 2083 implied HN points β€’ 29 Aug 23
  1. Major media outlets are echoing the need to stop the spread of Covid to reduce strain on hospitals.
  2. There are concerns about the possibility of another lockdown due to rising Covid cases and the emergence of new variants.
  3. Lockdowns had significant negative impacts on liberty and prosperity, with no apologies or accountability from those in charge.
A Biologist's Guide to Life β€’ 87 implied HN points β€’ 02 Mar 24
  1. Being unconventional in the academic world can lead to resistance and pushback from those in power, but staying true to your discoveries and principles is important.
  2. Challenging orthodox beliefs and standing by your heterodox views may result in alienation and hostility, but it can also lead to personal growth and self-discovery.
  3. Navigating the path of heterodoxy requires courage, resilience, and a willingness to face criticism and rejection, but in the end, it can lead to finding a community of like-minded individuals and true allies.
Injecting Freedom β€’ 45 implied HN points β€’ 08 Mar 24
  1. The post discusses whether the polio vaccines used in the United States can stop infection and transmission of the polio virus, focusing on the IPV vaccine mandated for grades K-12.
  2. It questions the effectiveness of the vaccine in preventing polio transmission in school settings, prompting readers to consider their answer of 'Yes' or 'No'.
  3. To access the full post and answer, readers are encouraged to subscribe for a 7-day free trial to the Injecting Freedom newsletter.
Anarchonomicon β€’ 1198 implied HN points β€’ 20 Jun 23
  1. American Conservatives and Jewish Conservatives are unique in maintaining above replacement fertility rates in wealthy societies.
  2. Conservative cultures that resist the global urban progressive monoculture tend to have higher fertility rates.
  3. American Conservatism exhibits adaptive immunity to the cultural influences that lead to declining birth rates in other cultures.
LIL Science β€’ 982 implied HN points β€’ 12 Jul 23
  1. The FDA committee recommended a monovalent vaccine for Fall 2023, targeting specific variants.
  2. A new variant, EG.5, is growing quickly and might pose challenges alongside other mutated variants.
  3. Despite numerous variants, severe waves of COVID-19 might be unlikely, but there is a concern regarding long-term impacts of infection.
LIL Science β€’ 727 implied HN points β€’ 21 Aug 23
  1. The arm in which you receive your COVID-19 booster might make a difference in your immune response.
  2. Getting the booster in the same arm as the previous dose could lead to higher neutralizing antibodies and specific T cells.
  3. Memory B cells may persist in the draining lymph node, potentially aiding quicker immune response upon re-exposure to the antigen.
Your Local Epidemiologist β€’ 1105 implied HN points β€’ 15 Jun 23
  1. COVID-19 vaccines are being updated for the fall 2023-2024 season due to fast mutations and waning effectiveness against hospitalization.
  2. Vaccine formula may shift to target only the Omicron XBB variant for better immune system recognition.
  3. Global alignment on focusing vaccine efforts on the XBB variant signals a step towards addressing the changing landscape of COVID-19.
Risk Musings β€’ 401 implied HN points β€’ 28 Oct 23
  1. Covid has become a global experience with waning immunity and increased contagiousness.
  2. Understanding Covid's spread involves looking beyond R0 numbers to factors like effective reproduction rate and incubation period.
  3. To combat Covid, focus on reducing susceptibility through therapeutics, policy changes like banning gain-of-function research, and investing in public health infrastructure.
Unreported Truths β€’ 54 implied HN points β€’ 27 Feb 24
  1. Vaccinated Covid patients in the Ohio State study had a higher risk of death compared to the unvaccinated, even after matching by age and comorbidities.
  2. Studies have shown that vaccinated Covid patients may not have a survival advantage once they are hospitalized. Other research supports the finding that vaccinated patients had higher mortality rates.
  3. The mRNA vaccines may not provide significant protection against severe disease or death in Covid-hospitalized patients according to multiple studies, contradicting previous claims about the effectiveness of the vaccines.
Unreported Truths β€’ 51 implied HN points β€’ 26 Feb 24
  1. A crucial line in the study was misread, leading to the need for a retraction of the article.
  2. The article incorrectly claimed that unvaccinated people were part of the study, when in fact all participants were vaccinated.
  3. The broader point still stands that there is increasing evidence vaccines may not prevent deaths once they stop preventing infection.
Injecting Freedom β€’ 29 implied HN points β€’ 12 Mar 24
  1. Tetanus vaccines used in the U.S. are part of a combination vaccine mandated for grades K-12 to prevent transmission of tetanus in school settings.
  2. Some believe that the tetanus vaccine stops infection and transmission of the tetanus bacterium.
  3. There is a 7-day free trial to access more information on the effectiveness of tetanus vaccines in preventing infection and transmission.
The COVID Digest β€’ 1100 implied HN points β€’ 18 Feb 23
  1. The author is taking a break from writing about COVID-19 after three years of pandemic updates.
  2. There has been a significant decrease in hospitalizations and ICU admissions in Georgia as waves of the pandemic progressed.
  3. The author emphasizes the importance of public health in addressing disparities and ensuring access to healthcare for all.
Injecting Freedom β€’ 15 implied HN points β€’ 15 Mar 24
  1. The diphtheria vaccine in the US is part of a combination vaccine mandated for grades K-12 to prevent transmission in schools.
  2. The diphtheria vaccine works to stop infection and transmission of the diphtheria bacterium.
  3. The belief behind the mandate is that the vaccine helps prevent the spread of diphtheria within the school setting.
Are You Okay? β€’ 698 implied HN points β€’ 28 Apr 23
  1. The effectiveness of population-level mask mandates is debatable, but wearing a high-quality, well-fitted mask consistently can provide some individual protection against infections.
  2. It's important to acknowledge that COVID is a persistent risk, and while vaccines and immunity help, individuals should assess their personal risk tolerance and take actions to mitigate their exposure.
  3. Stay informed and proactive in managing personal health, including staying up-to-date on vaccinations, addressing underlying health conditions, and boosting overall immunity through nutrition, exercise, sleep, and stress management.
Logging the World β€’ 498 implied HN points β€’ 16 May 23
  1. When reading articles about COVID variants, pay attention to which experts are being referenced and their specific expertise to evaluate the credibility of the information.
  2. Consider the rate of growth in absolute numbers and calibrate it against recent omicron waves to understand the impact of a new variant.
  3. Take early alarming estimates of growth rates with caution, as it may not reflect the long-term impact until the variant reaches a significant market share.
Logging the World β€’ 338 implied HN points β€’ 06 May 23
  1. The concern now is about the rising baseline of COVID infections, not just the peak waves.
  2. The occupancy of COVID beds has decreased since the Omicron variant, with fewer 'for COVID' patients compared to 'with' patients.
  3. The picture of COVID trends shows various spikes with falling peaks, hinting at potential further decreases in primary beds occupied in the upcoming weeks.
Logging the World β€’ 239 implied HN points β€’ 25 May 23
  1. Current COVID situation in the UK is relatively stable with low hospitalizations and deaths due to gained immunity from vaccines. Admissions and hospital pressures are encouragingly low.
  2. The growth rate of the XBB.1.16 variant is comparable to previous variants, indicating a smaller wave of cases. Expectations are calibrated based on past trends.
  3. Calls for increased masking at this point may not be effective as the R number would likely return to current levels after a short-term mask-wearing period. Public readiness to wear masks may have diminished.
DrV’s Newsletter, Notes, Essays, Articles, Videos, and Book Chapters β€’ 176 implied HN points β€’ 28 Mar 23
  1. The definition of 'vaccine' was broadened during the pandemic to include new drugs for legal and public acceptance.
  2. Ronald Reagan's policy granted financial and legal immunity to drug companies by categorizing new drugs as vaccines.
  3. The original definition of 'vaccine' was changed to protect the drug industry and now even covers agents like vitamin D.
Splitting Infinity β€’ 19 implied HN points β€’ 04 Oct 23
  1. Evolution plays a crucial role in the development of pathogens where they adapt quickly to evade the immune system.
  2. The level of virulence of a pathogen depends on a tradeoff between its ability to spread and the health of the host.
  3. Virulence management is an approach that aims to make pathogens evolve into less harmful strains through changing the evolutionary context in which they exist.
Joshua Gans' Newsletter β€’ 39 implied HN points β€’ 16 Sep 20
  1. The effectiveness of a COVID-19 vaccine may need to be higher than what regulatory bodies find acceptable in order to truly impact the course of the pandemic.
  2. Even with a vaccine that is 50% effective, wiping out the virus completely may be challenging, especially with lower vaccine coverage.
  3. Vaccines not only need to protect individuals from the virus but also prevent transmission to others, which can have a significant impact on overall disease spread.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 06 Apr 22
  1. When your Covid symptoms abate, you're likely still infectious. Consider "test to leave" or wear a mask after feeling better.
  2. Even after recovering from a cold or flu, continue to wear masks to reduce the spread of illnesses.
  3. With endemic Covid, it's crucial to focus on post-symptomatic measures rather than blanket requirements on asymptomatic individuals.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 29 Jan 22
  1. A new Omicron variant, BA.2, has emerged and appears to be 1.5 times as transmissible as the original BA.1 variant, leading to concerns about rapid spread.
  2. Studies suggest that BA.2 is not more lethal than Omicron and current vaccines are effective in preventing serious illness.
  3. There are concerns about potential reinfections with Omicron, as evidence shows higher reinfection rates and possible waning immunity within just 10 weeks.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 15 Dec 21
  1. The forecasted surge in Covid-19 cases for early 2022, particularly due to factors like reduced mitigation efforts, insufficient vaccination rates, and new variants, appears to be unfolding with the Omicron variant spreading rapidly.
  2. Preparation for the upcoming outbreaks includes obtaining N95 masks and rapid tests, having a plan to care for vulnerable individuals cautiously, and prioritizing booster shots for older individuals.
  3. Despite the likelihood of increased Covid-19 cases in the near future, the message emphasizes the importance of patience over panic, with outbreaks expected to be intense but relatively short-lived.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 16 Oct 21
  1. NSW and Ontario were used as comparison cases for the Delta variant, with NSW passing 80% of its 16+ population fully vaccinated and starting to ease restrictions.
  2. In Ontario, despite concerns of an outbreak when kids returned to school, the outbreak was relatively stunted compared to NSW, showcasing the value of vaccination over lockdowns.
  3. Winter will be the true test of resilience for vaccinations in Ontario, as well as dealing with waning immunity that will hit Ontario sooner than NSW.
News from Those Nerdy Girls β€’ 0 implied HN points β€’ 24 Mar 23
  1. A past COVID-19 infection provides good protection against re-infection and severe disease, if you survived the first infection.
  2. Vaccination remains the safest way to build immunity and protect against future encounters with the virus.
  3. Hybrid immunity, a combination of vaccine and infection-induced immunity, offers better protection against re-infection and severe disease.
The GIZN Journal of Medicine β€’ 0 implied HN points β€’ 11 Feb 24
  1. Receiving the COVID-19 vaccine during pregnancy does not pose risks to newborns and may offer protection against severe complications.
  2. Paxlovid has shown effectiveness in treating mild to moderate COVID-19 cases during the Omicron epidemic.
  3. After chimeric antigen receptor T-cell therapy, a study found a 27% incidence of CMV reactivation, but no patients developed CMV end-organ disease.