The hottest Designer Drugs Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

Designer Drug Exposé: Amphetamines & Other Stimulants

Tripsitter • 139 implied HN points • 04 Jan 24
🏥 Health & Wellness Designer Drugs Psychedelics
  1. Stimulants like amphetamines boost certain brain chemicals to increase alertness and energy. Cocaine, meth, and MDMA are well-known, but there are many more stimulants available.
  2. The use of stimulating herbs like ma huang dates back to ancient China for treating conditions like asthma and congestion.
  3. Designer amphetamines, fluorinated amphetamines, synthetic cathinones ("Bath Salts"), and MDXX class compounds are popular in the designer drug market, offering a range of effects from stimulant to psychedelic.

Designer Drug Exposé: Introduction To Research Chemicals 🧪

Tripsitter • 159 implied HN points • 28 Sep 23
🏥 Health & Wellness Designer Drugs Regulations Risks Harm Reduction History
  1. Designer drugs are synthetic substances meant to simulate the effects of known psychoactive drugs but with modified chemical structures to avoid legal restrictions.
  2. Designer drugs pose inherent risks like dosing variability, impurities, unknown toxicity, and dangers from unscrupulous vendors, highlighting the importance of harm reduction practices.
  3. The history of designer drugs spans decades, evolving through different eras with the introduction of AI-driven drug discovery, increased regulatory challenges, and a growing market of novel psychoactive substances.

Designer Drug Exposé: Psychedelic Phenethylamines

Tripsitter • 99 implied HN points • 07 Nov 23
🏥 Health & Wellness Psychedelics Designer Drugs
  1. Designer drug phenethylamines range from psychedelic to stimulant effects, with most falling in the middle, offering a blend of energizing and psychedelic qualities.
  2. Prominent designer phenethylamines include Benzofurinated 2CX drugs, Proscaline, and DOC compounds, each offering unique effects and properties.
  3. NBOMes, a subclass of NBX phenethylamines, are notably potent and often used as a dangerous alternative to LSD, with a high risk of toxicity and overdose.

Designer Drug Exposé: Lysergamides

Tripsitter • 79 implied HN points • 16 Dec 23
🏥 Health & Wellness Psychedelics Designer Drugs Safety Chemistry
  1. Lysergamides like LSD are potent psychedelics with similar effects, challenging one's sense of self and reality.
  2. Designer lysergamides, such as 1P-LSD and ALD-52, mimic the effects of LSD and are often converted into active LSD in the body.
  3. Legal complexities surround lysergamides with only LSD explicitly listed as a controlled substance, leading to the creation of various analogs and prodrugs.

Designer Drug Exposé: Tryptamine Psychedelics

Tripsitter • 79 implied HN points • 12 Oct 23
🏥 Health & Wellness Psychedelics Designer Drugs
  1. Tryptamine psychedelics include a wide variety of molecules that can profoundly alter consciousness and sensory perception.
  2. Many naturally occurring psychedelic tryptamines are banned in various countries, while synthetic analogs continue to be developed.
  3. Different groups of designer tryptamines have unique effects, such as the N-allyated tryptamines being less psychedelic than others.
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