The hottest Detoxification Substack posts right now

High oxalate levels might be due to seed oils leading to glyoxal production which is a major source of oxalate.
Reducing consumption of seed oils in favor of tropical oils, olive oil, and grass-fed animal fats might help lower oxalate production.
Nutrients like biotin, B12, and folate play roles in detoxifying oxalate, and checking for energetic bottlenecks through comprehensive screenings can help address oxalate issues.

Molybdenum is crucial for converting toxic sulfite to useful sulfate in the body. Deficiency can lead to various health issues like anxiety, sleep problems, and more.
Lab testing for molybdenum status is often inadequate, with tests focused on ruling out toxicity rather than assessing deficiency.
A simple DIY home test for molybdenum status can be done with minimal equipment, a molybdenum supplement, and a few days of data collection, providing a potentially more practical approach to monitoring levels.

B12 and folate can help detoxify oxalate by converting it to formate and joining it to tetrahydrofolate in a two-step process.
The rate of the first detoxification step exceeding the rate of the second step can lead to oxalate dumping symptoms.
Nutritionally supporting the two detoxification steps requires biotin, manganese, tetrahydrofolate, B12, and various other nutrients.

The hypothesis presented suggests that biotin-dependent enzyme pyruvate carboxylase may detoxify oxalate by converting it to formate, which could then be utilized in methylation or further metabolism.
Biotin deficiency might lead to oxalate intolerance, implying the importance of biotin in promoting oxalate clearance.
The interesting discussion around biotin and oxalate interactions opens up possibilities for further research into how biotin may play a role in detoxifying oxalate, potentially impacting how we approach certain health conditions.

Molybdenum plays important roles in sulfur handling, uric acid regulation, detoxification, and DNA protection.
Chris Masterjohn, PhD, delves into the significance of molybdenum in health and nutrition.
Accessing in-depth content on molybdenum and other nutrients may require a subscription on the provided website.

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Earth's health depends on the health of its ecosystems and species.
The environmental movement should focus on protecting intact ecosystems from further development.
Reverence for life in all forms is crucial for environmental healing.

It's important to thoroughly investigate and identify the root cause of health problems, rather than making assumptions without access to all the necessary data.
Symptoms and conditions can have multiple potential causes, highlighting the need for expert analysis and evaluation tailored to an individual's case.
Financial interests should not cloud judgment when evaluating health concerns, and transparency about revenue sources is essential.

The liver does not filter toxins, but helps in eliminating them through bile, feces, and urine
Hepatic detoxification occurs in three phases, modifying toxins to make them less toxic and water-soluble
It's important to correct the misunderstanding that the liver is a filter by educating others at different levels of scientific understanding

Statins inhibit squalene synthesis by cutting off cholesterol synthesis prior to the formation of squalene, which is a cholesterol precursor.
Squalene acts as an antioxidant, accumulating in the skin to prevent oxidative damage from UV light and has potential detoxifying effects.
Squalene might have anti-cancer properties, preventing the initiation of some cancers and aiding in the regression of certain tumors.