The hottest Patient Outcomes Substack posts right now

And their main takeaways

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Top Health & Wellness Topics

Small Trials vs Large Trials

Sensible Medicine • 2279 implied HN points • 29 Jan 24

🏥 Health & Wellness Medical Studies Clinical Trials Patient Outcomes Research Methods

Small trials may show larger treatment effects, but we should be skeptical of these results.
Large trials are valuable in confirming or refuting the findings of small trials.
Trials with composite endpoints can make it challenging to communicate treatment efficacy to patients.

Freakonomics, But for Medicine

Range Widely • 1159 implied HN points • 11 Jul 23

🏥 Health & Wellness Medicine Public Health Patient Outcomes

Natural experiments in medicine provide unique research opportunities that can't be replicated in a lab setting.
Even small disruptions, like marathon road closures, can have significant impacts on public health and mortality rates.
Factors like doctor's prescribing habits and patient age can have lasting effects on opioid use and patient outcomes.

Evaluating Medical Literature: Patient Oriented Evidence vs. Disease Oriented Evidence

News from Those Nerdy Girls • 511 implied HN points • 09 Jan 24

🏥 Health & Wellness Medical Studies Patient Outcomes Health Communication

When evaluating medical studies, focus on patient-oriented evidence that looks at outcomes meaningful to real people.
Disease-oriented evidence is more common but may not provide helpful insights into patient outcomes.
Be cautious of drawing conclusions about patient-oriented outcomes from disease-oriented evidence.

The Amount of Naloxone We're Giving Cops Is Too Damn High

The Medicine & Justice Project • 59 implied HN points • 28 Mar 24

🏥 Health Politics Opioid Crisis Adverse Effects Patient Outcomes Public Health

Naloxone, also known as Narcan, is an effective opioid overdose intervention that can be administered nasally with minimal training.
Administering too much naloxone can lead to unnecessary side effects, including inducing withdrawal symptoms that can be as severe as the opioid overdose itself.
Higher doses of naloxone may not necessarily improve patient outcomes and could increase the risk of adverse effects, such as flash pulmonary edema.

What's the effect of age on physician ability?

Perambulations • 16 implied HN points • 15 Mar 24

🏥 Health & Wellness Aging Patient Outcomes

Physician aging can impact patient outcomes, with evidence showing higher mortality rates when treated by older physicians compared to younger ones.
Factors like patient volume and board certification may offset risks associated with older physicians.
Cognitive decline with age can affect physician ability, but not all older physicians experience decline in patient outcomes.

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