The Healthtech Initiative • 0 implied HN points • 17 Mar 26
- People taking GLP-1s take fewer steps—activity drops on medication days and stays lower for about seven days.
- Resting heart rate rises and heart-rate variability (HRV) falls 2–7 days after dosing, indicating a shift in autonomic markers in a potentially concerning direction.
- These patterns were consistent across 538 people using a within-person comparison, so they reflect population-level trends captured by wearables rather than isolated outliers, though the analysis is conservative and correlation-only.