The hottest Side Effects Substack posts right now

And their main takeaways
Category
Top Health & Wellness Topics
Harnessing the Power of Nutrients β€’ 519 implied HN points β€’ 12 Jun 24
  1. Iron absorption may not significantly increase with alternate-day dosing compared to daily dosing because total iron absorbed per unit time may fall.
  2. Studies comparing daily iron dosing to alternate-day dosing suggest that 30-40 milligrams of iron per day can be safer and as effective as larger doses.
  3. Alternate-day dosing of iron supplements may introduce complications without providing additional benefits compared to a consistent daily dose.
Alexander News Network -Dr. Paul Elias Alexander's substack β€’ 1650 implied HN points β€’ 25 Jan 24
  1. Dr. Γ–zlem TΓΌreci, co-creator of first Pfizer COVID mRNA vaccine, has facial paralysis.
  2. Question raised about whether her work caused her facial paralysis.
  3. Concern about silence from medical doctors and media regarding facial paralysis.
Weight and Healthcare β€’ 1118 implied HN points β€’ 10 Jan 24
  1. Ozempic and Wegovy are different brand names for the same drug used for weight loss.
  2. Wegovy is not just a weight loss drug but a megadose of a diabetes drug with weight loss as a side effect.
  3. Wegovy has serious side effects including complications when going off the drug and the need for continuous use to maintain weight loss.
Weight and Healthcare β€’ 818 implied HN points β€’ 10 Feb 24
  1. The study on Tirzepatide showed that weight loss for participants slowed after 36 weeks, with those switching to placebo experiencing weight regain while those continuing the drug had a slight weight reduction in the following 52 weeks.
  2. Side effects of Tirzepatide included gastrointestinal issues like nausea, diarrhea, constipation, and vomiting. Close to 82% of participants reported experiencing at least one adverse event during the treatment period.
  3. The study's findings indicate that a significant percentage of participants taking Tirzepatide did not meet the weight reduction thresholds, with a lack of diverse representation among participants and a lack of a weight-neutral comparator group presenting issues in the study design.
Weight and Healthcare β€’ 818 implied HN points β€’ 03 Feb 24
  1. Tirzepatide, known as Zepbound for weight loss, was initially a Type 2 diabetes medication by Eli Lilly that got FDA approval for weight loss due to its side effect of weight loss. It works by interfering with normal digestion processes and hunger signals.
  2. There are dosing differences between the diabetes and weight loss applications of Tirzepatide. For weight loss, patients are encouraged to continuously increase the dosage to the highest tolerable level, potentially facing side effects that impact their quality of life.
  3. The side effects of Tirzepatide/Zepbound can range from mild discomfort to serious conditions like thyroid C-Cell tumors, gastrointestinal diseases, and pancreatic issues. Patients need to be aware of potential risks, like drug interactions and impact on pregnancy.
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Weight and Healthcare β€’ 798 implied HN points β€’ 01 Nov 23
  1. Healthcare practitioners should provide informed consent without patients having to ask for it, and dismissing concerns about side effects violates medical ethics.
  2. Wegovy, a weight loss medication, has serious side effects including contraindications for certain medical conditions, fetal harm, and common side effects like nausea and abdominal pain.
  3. The FDA-approved documentation and research show significant adverse events associated with Wegovy, challenging the idea that the drug is safe and raising important questions about long-term use.
Weight and Healthcare β€’ 579 implied HN points β€’ 04 Nov 23
  1. Wegovy is a weight-loss drug that has not been around for a long time, as it is a repurposed version of another drug called semaglutide, with evolving risks and warnings.
  2. Wegovy and Ozempic differ in dosage and treatment purpose, with Wegovy aiming to maximize weight loss side effects at a high dose that exceeds the maximum dose of Ozempic.
  3. Informed consent conversations with healthcare practitioners are essential, especially when considering drugs like Wegovy with significant side effects and dosage differences.
Weight and Healthcare β€’ 738 implied HN points β€’ 17 Aug 22
  1. Weight loss drugs often lead to short-term weight loss followed by weight regain, with participants regaining a significant amount of weight and cardiometabolic gains after going off the drug.
  2. Wegovy and Tirzepatide, new weight loss drugs, show a pattern of rapid weight loss at the beginning, then levelling off, and potential weight regain later. Side effects of these drugs are serious.
  3. Pharmaceutical companies aim for profits by keeping patients on expensive weight loss drugs long-term, despite minimal evidence of long-term weight loss benefits and significant harm from side effects.
The Frontier Psychiatrists β€’ 117 implied HN points β€’ 09 Feb 24
  1. Remeron, also known as Mirtazapine, has unique side effects like making you sleepy and increasing appetite due to its histamine effects.
  2. While Remeron may not differ significantly in its antidepressant effects from other drugs, it could work slightly faster and be more favorable in treating depression compared to SSRIs.
  3. A meta-analysis suggests that overall, Remeron might have a slight edge over SSRIs in treating depression, making it potentially a better option for some individuals.
Tripsitter β€’ 139 implied HN points β€’ 14 Jan 24
  1. Xylazine, also known as tranq, is a horse tranquilizer that has made its way into illicit drug use by being combined with substances like heroin and fentanyl.
  2. The heavy sedative effects of xylazine can lead to severe skin issues, with users having necrosis and sores that can go down to the bone, contributing to its 'zombie drug' nickname.
  3. Xylazine causes a range of side effects and can increase the risk of opioid overdose, acting as a significant danger when mixed with other substances and having no known safe agents for reversal in humans.
Tripsitter β€’ 59 implied HN points β€’ 17 Apr 24
  1. The Mexican Dream Herb, Calea zacatechichi, is known for enhancing dream vividness and helping in lucid dreaming.
  2. Traditional shamans use Calea for ceremonial purposes and other benefits like relief from digestive disorders.
  3. Using Calea can lead to hyper-realistic and coherent dreams by affecting sleep stages N1 and REM, which can help in extracting knowledge from dreams.
Weight and Healthcare β€’ 479 implied HN points β€’ 22 Oct 22
  1. Weight loss research should be at least five years long to capture long-term outcomes accurately.
  2. The weight loss industry often conducts short-term studies that may overlook weight regain and potential harms of interventions.
  3. There is a need for systemic change in how weight loss interventions are researched and marketed to protect patients from ineffective and potentially harmful treatments.
The Frontier Psychiatrists β€’ 196 implied HN points β€’ 14 Jun 23
  1. Data shows a highly effective depression treatment named deep TMS exists.
  2. Real-world application of this treatment has led to remission in 65% of patients with treatment-resistant depression.
  3. Insurance coverage policies often prevent patients from accessing the most effective treatments.
Are You Okay? β€’ 139 implied HN points β€’ 20 Aug 23
  1. The flu is a respiratory illness caused by the Influenza virus, with symptoms like cough, sore throat, fever, body aches, and fatigue. It can be severe and even fatal.
  2. Getting a flu vaccine is crucial because it reduces the risk of serious flu-related complications and mortality. Even if its effectiveness varies, it plays a significant role in preventing deaths.
  3. The flu spreads person-to-person and in the air, especially in crowded, poorly ventilated indoor spaces. Effective treatments include prescription antiviral medications and rest.
Tripsitter β€’ 99 implied HN points β€’ 22 Nov 23
  1. Breath can shift states and induce different experiences like calmness, energy, or even psychedelic effects.
  2. Psychedelic breathwork involves rhythmic breathing patterns to induce altered states and can have physical sensations, emotional releases, and even visions.
  3. Psychedelic breathwork can be safe for most mentally and physically healthy individuals, but certain conditions should avoid it, and side effects can include dizziness, tingling, cramps, among others.
Tripsitter β€’ 99 implied HN points β€’ 14 Nov 23
  1. Morning glory vine contains psychedelic compounds similar to LSD, with LSA being naturally occurring and less potent than LSD.
  2. Morning glory has been traditionally used in shamanism in Central American cultures for divination and healing purposes.
  3. Morning glory played a significant role in Aztec and Mayan cultures as a divine plant for rituals and ceremonies.
eugyppius: a plague chronicle β€’ 353 implied HN points β€’ 23 Apr 23
  1. German reporting is focusing more on vaccine injuries from mRNA jabs.
  2. This shift has been driven by popular interest, contrary to previous enthusiasm for vaccines.
  3. The pharmaceutical industry's profits have not matched the success of their mRNA vaccines.
Tripsitter β€’ 99 implied HN points β€’ 14 Aug 23
  1. Preparation and knowledge are key to ensuring a safe and enjoyable experience when taking MDMA.
  2. It's important to test MDMA for purity and avoid pressed pills due to varying dosage and potential contamination issues.
  3. Understanding the risks, dosage guidelines, and effects timeline of MDMA is crucial for harm reduction and safety.
Unmasked β€’ 88 implied HN points β€’ 06 Mar 24
  1. Booster mandates in colleges may have harmed millions of students, causing potentially damaging side effects without significant health benefits.
  2. An admission from a former FDA director highlighted flaws in the COVID vaccine approval process, leading to unnecessary mandates for young individuals.
  3. Specific data is being gathered to reveal the harmful impact of these mandates on college students, shedding light on the negative consequences.
Tripsitter β€’ 79 implied HN points β€’ 17 Jul 23
  1. The lemon tek method of preparing magic mushrooms can lead to faster onset of effects, stronger psychedelic experiences, improved taste, and reduced nausea.
  2. Lemon tek may increase the potency of magic mushrooms by up to 20%, potentially due to the conversion of psilocybin to psilocin and the protective effects of vitamin C.
  3. Lemon tek can help eliminate common side effects of magic mushrooms like 'gut rot' and can kick in more quickly than consuming raw mushrooms, with effects starting within 20-45 minutes.
Vinay Prasad's Observations and Thoughts β€’ 71 implied HN points β€’ 07 Mar 24
  1. Results that seem too good to be true may not be accurate and can hide potential harms or biases.
  2. Confounded studies, where data is influenced by other factors, can be misleading and unhelpful in drawing conclusions.
  3. It's important to consider the full data and potential biases in research studies, especially when interpreting studies involving vaccinations during pregnancy.
Tripsitter β€’ 59 implied HN points β€’ 02 Oct 23
  1. Hawaiian Baby Woodrose seeds contain the highest concentration of LSA, a natural psychedelic compound, found in nature.
  2. LSA in HBWR has different effects than LSD, causing more physical effects and a 'chill' psychedelic experience at standard doses.
  3. Traditional use of HBWR seeds for psychedelics traces back to the 1960s, mainly associated with the New Age religion Huna in Hawaii.
semaglutide β€’ 39 implied HN points β€’ 16 Mar 23
  1. Be wary of potential deadly side effects of popular weight loss drugs like Ozempic and Wegovy.
  2. Weight Watchers and NHS are incorporating weight loss drugs like Wegovy into their programs.
  3. The high costs and potential health risks associated with weight loss medications raise concerns about accessibility and effectiveness.
Unreported Truths β€’ 55 implied HN points β€’ 02 Feb 24
  1. Vaccinating almost 38,000 kids may prevent one COVID hospitalization, but with hundreds of serious side effects.
  2. For people aged 5-15, the mRNA COVID jabs are not very effective, according to a British study.
  3. The study indicates that vaccination effectiveness varies by age group, with the shots being more beneficial for the elderly than for children.
Off-Topic β€’ 23 HN points β€’ 23 Jun 23
  1. The Benadryl Challenge on TikTok has resulted in serious and fatal consequences, prompting calls for age restrictions and social media regulation.
  2. The appeal of consuming Benadryl lies in its hallucinogenic effects, transporting users to a delirious realm where reality blurs with fiction.
  3. Benadryl misuse can lead to severe physical symptoms, hallucinations, and encounters with entities like the Hatman, showcasing the dangerous repercussions of recreational drug use.
Steve Kirsch's newsletter β€’ 13 implied HN points β€’ 19 Feb 24
  1. The CDC has released V-safe free-text comments to show the serious safety problems associated with the COVID vaccine.
  2. There are nearly 400,000 comments in the release, highlighting a variety of negative symptoms and reactions.
  3. Using testimonials from V-safe comments could be a powerful marketing tool to encourage vaccine uptake.
Harnessing the Power of Nutrients β€’ 0 implied HN points β€’ 15 Apr 20
  1. Recent studies show that hydroxychloroquine may not be effective in treating COVID-19, despite initial hype.
  2. Hydroxychloroquine did not impact viral clearance or symptom relief in patients, based on study results.
  3. Potential side effects of hydroxychloroquine, including heart rhythm abnormalities, raise concerns about its safety in severe COVID-19 cases.
Are You Okay? β€’ 0 implied HN points β€’ 20 Jan 21
  1. More COVID-19 vaccine doses are on the way, including a safe single-dose option from Johnson & Johnson.
  2. Stay patient with booking vaccine appointments, as more doses are being distributed, and federal efforts are underway to speed up the process.
  3. Prepare for your vaccine appointment by ensuring you're well-rested and well-fed, but avoid premedicating with Benadryl if you have allergies.
Are You Okay? β€’ 0 implied HN points β€’ 25 Oct 21
  1. Boosters are recommended for certain groups like those over 65 or with chronic conditions, and timing varies depending on the initial vaccine received.
  2. It's important to consider the type of booster based on individual health and risks, with options like sticking with the original vaccine or mixing and matching for added protection.
  3. Side effects from booster shots are similar to initial vaccines, so it's advisable to plan for a day or two for potential reactions like fatigue or arm soreness.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 06 Jan 21
  1. Israel's efficient vaccine distribution showcases excellent preparation and organization.
  2. Israel has a unique opportunity to provide insights into the effectiveness of vaccination against COVID-19.
  3. Israel's approach to vaccine distribution may offer hope for addressing long-term problems, such as providing vaccines to neighboring territories.
The False Consensus Effect β€’ 0 implied HN points β€’ 08 Jan 21
  1. Taking medication for heart conditions can have various side effects, some possibly worsening the initial issue.
  2. The author questions the conventional medical approach to treating heart diseases, advocating for a more personalized and holistic approach.
  3. The text highlights the importance of individualized care from healthcare professionals rather than a one-size-fits-all treatment approach.
Gutsphere - Your Ultimate Guide to Optimal Gut Health β€’ 0 implied HN points β€’ 31 May 23
  1. Laxatives can interact with other medications, affecting their effectiveness and causing side effects.
  2. Long-term laxative use may impact mental health by altering gut microbiota, potentially leading to mood disorders.
  3. Laxatives should be used cautiously in children and the elderly, under healthcare provider supervision, due to potential risks and interactions.
semaglutide β€’ 0 implied HN points β€’ 22 Mar 23
  1. To dose Ozempic for weight loss effectively, start with a low dosage and gradually increase under a doctor's supervision.
  2. Common side effects of Ozempic can include nausea, vomiting, and diarrhea, so it's important to consult your doctor if any side effects occur.
  3. In addition to medication, successful weight loss may also require lifestyle changes like a balanced diet, increased physical activity, and setting achievable goals.