The hottest mRNA Substack posts right now

mRNA vaccines can lead to production of unwanted proteins due to reading errors in cells
Research suggests that these off-target proteins do not raise significant safety concerns about mRNA vaccines
Even though concerns exist about off-target proteins, experts suggest that mRNA vaccines are still considered safe

There were initial doubts about a vaccine for COVID-19 being developed quickly.
The Nobel Prize was not for inventing mRNA vaccines, but for a breakthrough in mRNA delivery in 2005.
mRNA vaccines have a wide range of potential applications beyond COVID-19, showing promise in various diseases and therapies.

Michael Strahan's daughter was diagnosed with medulloblastoma, a rare form of brain cancer.
There is mention of a potential gene vaccine that could help with the cancer.
The post raises the question of whether Michael should consider specific mRNA vaccines.

A recent study presented the first evidence that vaccine spike protein mRNA can be reverse transcribed into DNA within human cells, although further validation is necessary.
Integration into chromosomes is not required to consider something 'written into the genome'; extrachromosomal circular DNA can also lead to gene expression and phenotypic changes.
The unexpectedly long persistence of mRNA and spike protein after vaccination raises concerns and suggests the need to investigate reverse transcription as a mechanism for this durability.

Özlem Türeci is a founder involved in mRNA research for cancer therapy and disease prevention.
Axial partners with and invests in early-stage life sciences companies to help rare inventors build enduring businesses.
They are excited to connect with individuals in the life sciences field who have innovative ideas or companies.

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