Maryanne Demasi, reports | Revenue & Trends

The hottest Substack posts of Maryanne Demasi, reports

And their main takeaways

mRNA vaccines can lead to production of unwanted proteins due to reading errors in cells
Research suggests that these off-target proteins do not raise significant safety concerns about mRNA vaccines
Even though concerns exist about off-target proteins, experts suggest that mRNA vaccines are still considered safe

A former TGA boss has been appointed to the board of Medicines Australia to advance mRNA technology in Australia.
John Skerritt, previously with TGA, reflects on his achievements in speeding up drug approvals during his time there.
Concerns are raised about the 'revolving door' practice where agency officials end up working for industries they once regulated.

Florida Surgeon General called for a halt in the use of mRNA COVID-19 vaccines due to concerns about DNA contamination.
He criticized the FDA and CDC for not adequately testing whether DNA fragments in the vaccine could integrate into a person's genome.
This action has sparked a debate about the safety of mRNA COVID-19 vaccines.

Fauci faced a two-day grilling under oath by the House Select Subcommittee on the Coronavirus Pandemic.
Questions were raised about Fauci's policy decisions that impacted many lives.
There were investigations on whether information about a possible lab leak was suppressed.

Rosuvastatin (Crestor®) quickly became a popular cholesterol-lowering drug due to an aggressive marketing campaign.
In Australia, rosuvastatin is the most prescribed drug, with over 14 million prescriptions written in a financial year.
Rosuvastatin was found to be the most potent statin in lowering cholesterol, but this higher potency also led to greater toxicity.

Get a weekly roundup of the best Substack posts, by hacker news affinity:

Pfizer had evidence early on that vaccine efficacy waned but delayed alerting the public
Regulators and Pfizer did not disclose data on waning immunity promptly
Public health experts emphasize the importance of transparency and honesty in reporting vaccine efficacy

The Cochrane review found that wearing masks in the community may not make much of a difference in preventing the spread of respiratory viruses like COVID-19.
Governments around the world have mandated mask-wearing, despite the lack of strong evidence supporting their effectiveness in pandemics.
Tom Jefferson, the lead author of the review, criticized the pandemic 'experts', questioned health policies, and expressed disappointment in how Cochrane handled the review.

The recent Cochrane review on physical interventions like face masks has sparked controversy.
Cochrane's statement about the review was seen as an apology and caused confusion.
Lead author Tom Jefferson's reaction to Cochrane's statement was unexpected.