The hottest Psychedelics Substack posts right now

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Designer Drug Exposé: Psychedelic Phenethylamines

Tripsitter • 99 implied HN points • 07 Nov 23
🏥 Health & Wellness Psychedelics Designer Drugs
  1. Designer drug phenethylamines range from psychedelic to stimulant effects, with most falling in the middle, offering a blend of energizing and psychedelic qualities.
  2. Prominent designer phenethylamines include Benzofurinated 2CX drugs, Proscaline, and DOC compounds, each offering unique effects and properties.
  3. NBOMes, a subclass of NBX phenethylamines, are notably potent and often used as a dangerous alternative to LSD, with a high risk of toxicity and overdose.

Designer Drug Exposé: Lysergamides

Tripsitter • 79 implied HN points • 16 Dec 23
🏥 Health & Wellness Psychedelics Designer Drugs Safety Chemistry
  1. Lysergamides like LSD are potent psychedelics with similar effects, challenging one's sense of self and reality.
  2. Designer lysergamides, such as 1P-LSD and ALD-52, mimic the effects of LSD and are often converted into active LSD in the body.
  3. Legal complexities surround lysergamides with only LSD explicitly listed as a controlled substance, leading to the creation of various analogs and prodrugs.

Not All Who Trip Are Transformed: Beware The Spiritual Narcissist 🙏❤️‍🩹

Tripsitter • 99 implied HN points • 22 Sep 23
⛪ Faith & Spirituality Psychedelics Enlightenment Self-awareness Ego
  1. Pseudo-spirituality and spiritual narcissism are prevalent in the psychedelic realm, where individuals may use spiritual practices to avoid personal growth.
  2. Recognizing spiritual egotism and the journey towards spiritual awareness involves acknowledging and confronting one's ego, rather than masking it through spiritual practices.
  3. Identifying traits of spiritual narcissists such as superiority complex, manipulation, and lack of empathy is crucial to safeguard oneself in the spiritual and psychedelic community.

Guardians of the Spirit Molecule: DMT Entities

Tripsitter • 99 implied HN points • 12 Jun 23
🏥 Health & Wellness Psychedelics Consciousness Research Metaphysics
  1. DMT entities are mysterious humanoid creatures that appear in psychedelic experiences on large doses of DMT.
  2. There are various theories about the origins of DMT entities, with explanations ranging from extraterrestrial communication to manifestations of the collective unconscious.
  3. DMT entities are reported to have a significant impact on individuals, with encounters often leading to emotional responses, positive interpretations, and lasting improvements in well-being.

MK-ULTRA & The CIA's Bizarre Psychedelic Escort Service

Tripsitter • 99 implied HN points • 08 Jun 23
💾 History Mind Control Conspiracies Psychedelics Experiments
  1. The CIA's MK-Ultra program involved using psychedelics for mind control and manipulation, leading to disturbing outcomes like forced confessions and personality alterations.
  2. Under MK-Ultra, experiments like Operation Midnight Climax and 'psychedelic driving' subjected individuals to involuntary drug doses, induced comas, and repeated messaging, resulting in severe negative effects on mental health.
  3. Conspiracies surrounding MK-Ultra include connections to infamous figures like the Unabomber, Charles Manson, and Jack Ruby, raising disturbing questions about the program's impact on society.
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Curator

Castalia • 139 implied HN points • 04 May 23
🎭️ Culture Art Literature Psychedelics Social Issues Morality
  1. Roland Griffiths has played a big role in bringing psychedelics back to scientific study, showing they can have real mental health benefits. His research has changed the way people think about psychedelics and their potential uses.
  2. There is a complicated debate about separating an artist's work from their personal character. While some believe that art can exist apart from the artist's morals, many feel uncomfortable consuming art created by people who have done bad things.
  3. The #MeToo movement is important, but it has complicated the way we view allegations and public accusations. Some cases, like that of Junot Díaz, show that not every accusation is entirely accurate, highlighting the need for careful investigation.

Shroom Science: How Strong is the Average Magic Mushroom? 🔍🍄

Tripsitter • 79 implied HN points • 24 Oct 23
🏥 Health & Wellness Psychedelics Species
  1. Magic mushrooms contain varying levels of psilocybin, psilocin, and baeocystin, with potency ranging from 0.1% to 3% depending on species and growing conditions.
  2. Psilocybe cubensis strains typically have around 0.60% to 0.90% total tryptamines, with strains like Golden Teacher and Koh Samui falling into this range.
  3. The most potent species of magic mushrooms is Psilocybe azurescens, while the most potent strain is Tidal Wave, with 3.82% total tryptamines, nearly five times the average potency.

Thought Loops: How Psychedelics Put the Brain on Repeat

Tripsitter • 59 implied HN points • 12 Dec 23
🏥 Health & Wellness Psychedelics
  1. Thought loops are repetitive and intrusive thoughts that can occur when using psychoactive drugs, but they are temporary and can be managed with the right mindset.
  2. Thought loops can feel frustrating, confusing, and disorienting, often centering around fears, regrets, or unresolved issues, and they are common with conditions like anxiety, depression, PTSD, schizophrenia, and psychosis.
  3. Methods to interrupt thought loops include deep breathing, redirecting attention, trying new activities, changing the environment, talking to someone for reassurance, and practicing surrendering to release stress.

High on the Present: Mindfulness Meets Mind-Altering

Tripsitter • 79 implied HN points • 13 Oct 23
🏥 Health & Wellness Mindfulness Psychedelics Brain function Presence
  1. Nearly 47% of our waking hours are spent distracted, leading to less happiness even with neutral thoughts.
  2. Living in the moment means fully engaging with the present environment and experiences, requiring letting go of past or future thoughts.
  3. Psychedelics like LSD and psilocybin are being researched for their potential to reduce default mode network activity, allowing the mind to be more receptive to the present moment.

Designer Drug Exposé: Tryptamine Psychedelics

Tripsitter • 79 implied HN points • 12 Oct 23
🏥 Health & Wellness Psychedelics Designer Drugs
  1. Tryptamine psychedelics include a wide variety of molecules that can profoundly alter consciousness and sensory perception.
  2. Many naturally occurring psychedelic tryptamines are banned in various countries, while synthetic analogs continue to be developed.
  3. Different groups of designer tryptamines have unique effects, such as the N-allyated tryptamines being less psychedelic than others.

Boracherro: The Flower That Charms & Harms

Tripsitter • 79 implied HN points • 24 Aug 23
🏥 Health & Wellness Psychedelics Plants Toxicity Folklore
  1. The Boracherro tree, also known as Angel's Trumpets, may seem beautiful but contains psychoactive compounds that can be deadly and induce intense hallucinations.
  2. Brugmansia, a genus of ornamental shrubs including Boracherro, have vibrant flowers and are extinct in the wild but abundant in cultivation, with psychoactive properties.
  3. Boracherro contains tropane alkaloids like scopolamine that can lead to delirium, vivid hallucinations, and dangerous side effects, emphasizing the importance of caution and shamanic guidance in its use.

Smoke & Mirrors: Revealing the Truth Behind Smoking Cessation With Psychedelics 🚬

Tripsitter • 79 implied HN points • 24 Jul 23
🏥 Health & Wellness Psychedelics
  1. Psilocybin-assisted psychotherapy showed high success rates in aiding smoking cessation, with identity reframing being a key factor.
  2. Cognitive behavioral therapy (CBT) before psilocybin sessions can dramatically impact treatment success by establishing positive thought patterns.
  3. Psychedelic-assisted identity shift is a theoretical mechanism for addiction treatment efficacy, emphasizing the importance of study methodology and setting in psychedelic research.

When Life Gives You Lemons... Mix Them With Magic Mushrooms 🍋 (Lemon Tek Guide)

Tripsitter • 79 implied HN points • 17 Jul 23
🏥 Health & Wellness Psychedelics Preparation Side Effects Dosage
  1. The lemon tek method of preparing magic mushrooms can lead to faster onset of effects, stronger psychedelic experiences, improved taste, and reduced nausea.
  2. Lemon tek may increase the potency of magic mushrooms by up to 20%, potentially due to the conversion of psilocybin to psilocin and the protective effects of vitamin C.
  3. Lemon tek can help eliminate common side effects of magic mushrooms like 'gut rot' and can kick in more quickly than consuming raw mushrooms, with effects starting within 20-45 minutes.

Getting Unstuck: How Psychedelics Can Help Navigate Mental Blocks 🧠

Tripsitter • 79 implied HN points • 01 Sep 23
🏥 Health & Wellness Psychedelics Creativity Mental health Problem Solving
  1. Psychedelics can help unlock creativity and uncover solutions to complex problems by increasing randomness in the brain.
  2. Psychedelics don't make us smarter or increase IQ, but they can aid in viewing problems from different perspectives.
  3. Randomness induced by psychedelics can lead to novel ideas and breakthrough moments that help in overcoming mental blocks.

Beyond LSD: The Enigmatic World of Lysergamide Psychedelics

Tripsitter • 79 implied HN points • 31 Jul 23
🏥 Health & Wellness Psychedelics Research Effects
  1. LSD is just one of over a dozen lysergamide compounds, each with unique effects and characteristics.
  2. Lysergamides mimic serotonin, interact with dopamine and norepinephrine, and can vary in potency and effects based on their chemical structure.
  3. Researchers have explored various lysergamides for potential mental health treatments, headache management, and artistic inspiration.

Dancing at Elsewhere

Splattern • 59 implied HN points • 20 Nov 23
🎭️ Culture Personal Growth Relationships Human experience Music Events Psychedelics
  1. Don't let fear stop you from doing what you want. Imagine doing it without fear and just go for it if you would do it then.
  2. Falling in love can be a beautiful experience. It's okay to enjoy that feeling without overthinking it.
  3. Taking time to connect with others and enjoy simple moments, like sharing a meal or reminiscing, is really rewarding.

Tripping Towards Self-Love: Psychedelics & Body Dysmorphic Disorder

Tripsitter • 59 implied HN points • 04 Aug 23
🏥 Health & Wellness Psychedelics Eating Disorders Mental health Therapies
  1. Body dysmorphic disorder is a serious condition with limited treatment options, but psychedelics might offer a new, promising avenue for treatment.
  2. Classic psychedelics like psilocybin, LSD, and ayahuasca have shown potential in disrupting thought patterns and providing relief to obsessive thoughts associated with body dysmorphic disorder.
  3. There is a need for more research and clinical trials to explore the effectiveness of psychedelics in treating body dysmorphic disorder and related body image issues.

Ape to Einstein? Exploring The Stoned Ape Theory

Tripsitter • 59 implied HN points • 25 Sep 23
🔬 Science Evolution Psychedelics Human Evolution Consciousness
  1. The Stoned Ape Theory suggests that early humans consuming psychoactive substances like magic mushrooms led to advancements in creative thinking, language development, and societal structure.
  2. American ethnobotanist Terence McKenna proposed the theory that psychoactive mushrooms catalyzed rapid brain development in early ancestors, leading to higher levels of consciousness.
  3. While the Stoned Ape Theory is intriguing, it lacks scientific evidence and faces criticism for oversimplifying the complexities of human evolution and consciousness.

The Peyote Way: Desert Wisdom & The Red Road 🌵

Tripsitter • 59 implied HN points • 10 Aug 23
🏥 Health & Wellness Psychedelics Medicine Conservation Ceremony History
  1. True understanding and knowledge are acquired over time, aligning with the growth habits and resilience of the peyote cactus.
  2. Peyote is a medicine with teachings of humility, perseverance, commitment, courage, gratitude, and love.
  3. The history of peyote involves a ban by the United States government, challenges with conservation, and its impact on consciousness and spiritual practices.

Hawaiian Baby Woodrose Seeds (HBWR): Naturally-Occurring LSA

Tripsitter • 59 implied HN points • 02 Oct 23
🏥 Health & Wellness Psychedelics Side Effects Dosage Preparation
  1. Hawaiian Baby Woodrose seeds contain the highest concentration of LSA, a natural psychedelic compound, found in nature.
  2. LSA in HBWR has different effects than LSD, causing more physical effects and a 'chill' psychedelic experience at standard doses.
  3. Traditional use of HBWR seeds for psychedelics traces back to the 1960s, mainly associated with the New Age religion Huna in Hawaii.

The Potential of Psychedelics

The Last Bear Standing • 43 implied HN points • 15 Mar 24
🏥 Health & Wellness Psychedelics Mental health Therapeutics Clinical Trials FDA Approval
  1. There has been a resurgence of interest in the medical potential of psychedelics, with ongoing research and clinical trials exploring their efficacy in treating mental health conditions.
  2. Despite the challenges and market fluctuations, there is increasing regulatory support for psychedelic drug trials, potentially leading to FDA approvals and breakthrough therapy designations for conditions like PTSD.
  3. Psychedelic treatments involve controlled drug administration in conjunction with therapy, aiming to address the root causes of mental health disorders by stimulating new perspectives and thought patterns.

From Ego to AI: AI as the path to the Age of Aquarius

Rob Leclerc • 19 implied HN points • 01 Mar 24
🕹 Technology AI Neuroscience Psychedelics Future of AI
  1. Fear of AI dominance may be influenced by our ego, but future AI-human symbiosis could be positive.
  2. The Default Mode Network in the brain plays a crucial role in shaping our self-identity and consciousness.
  3. As AI technology advances, it may lead to changes in human consciousness, potentially altering our sense of self and cognitive abilities.

Some Thoughts on LSD

Castalia • 119 implied HN points • 05 Nov 22
⛪ Faith & Spirituality Psychedelics Personal Growth Mindfulness Philosophy
  1. LSD can really change how you feel and see the world. Many people feel more open, creative, and less anxious after using it.
  2. The experience of taking LSD can lead to personal growth and a sense of purpose. Some might even feel more confident in following their own path.
  3. Using LSD and similar substances can bring about a new understanding of reality. It might even lead to feeling grateful and connected to everything around you.

Who Guides the Guide? The Wild West of Psychedelic Coaching

Tripsitter • 19 implied HN points • 30 Jun 23
🏥 Health & Wellness Psychedelics Therapy Integration
  1. In the field of psychedelic coaching, there are varying levels of experience and training among guides, from traditional shamans to underground guides.
  2. Certification programs are emerging to increase access to psychedelic treatment, but the necessity of firsthand psychedelic experience for facilitators is a debated topic.
  3. The future of psychedelic therapy includes efforts to create accountability and standardization, such as ethical reputation scoring systems for facilitators and guides.

From Maple to Mind Expansion: Unveiling Canada's Psychedelic History with Erika Dyck 🍁

Tripsitter • 19 implied HN points • 14 Jul 23
🏥 Health & Wellness Psychedelics Mental health Medical Research Addiction Treatment Healthcare system
  1. Psychedelics have a long and complex history in Canada, ranging from being viewed as panaceas in the 1950s to being labeled dangerous drugs until recently, but now are being integrated into healthcare for various treatments.
  2. Early Canadian psychedelic research focused on themes of intrigue, sympathy, and addiction, which contributed to a deeper understanding of psychosis, schizophrenia, and treatment for conditions like alcoholism.
  3. Factors like the Thalidomide scandal, countercultural movement, public sensationalism, and loss of scientific naivete contributed to the decline in public support for psychedelics in Canada, leading to prohibitive measures and shifting perceptions of medicine and healthcare providers.

Ayahuasca

Integrity Talk • 66 implied HN points • 19 Feb 23
🏥 Health & Wellness Psychedelics Personal Growth Mental health Self-awareness Shamanism
  1. The journey into the world of shamanic healing can offer diverse experiences in different settings and with various participants.
  2. Experiencing Ayahuasca ceremonies can lead to deep introspection and self-acceptance, providing a unique perspective on one's own traits and behaviors.
  3. Participating in communal shamanic rituals can create a sense of warmth and transcendence, offering communal benefits and the opportunity for self-awareness and personal growth.

Psychedelics and Climate Change

Daniel Pinchbeck’s Newsletter • 20 implied HN points • 04 Feb 24
🏥 Health & Wellness Psychedelics Climate change Consciousness Philosophy Science
  1. The psychedelic movement is being assimilated by mainstream institutions and corporate structures, losing its original depth and spontaneity.
  2. Contemporary Western society often strips away the soul and spirit from encounters, leaving behind desiccated husks.
  3. Analytic idealist philosophy suggests approaching the world as a system of allegories, laden with meaning, similar to how animist ancestors and indigenous people viewed it.

Mirror, Mirror on the Wall: Can Psychedelics Deflate the Biggest Ego of Them All?

Tripsitter • 19 implied HN points • 08 Jun 23
🏥 Health & Wellness Psychedelics Narcissism Empathy Therapy Research
  1. Narcissism is a spectrum that ranges from mild traits to Narcissistic Personality Disorder (NPD), requiring specific conditions for diagnosis.
  2. Psychedelics show potential in addressing narcissism through enhancing empathy, inducing awe and ego dissolution, and promoting connectedness and transcendence.
  3. Psychedelics can aid in reducing narcissistic traits, but long-lasting change requires post-experience integration and may be challenging due to the complexity of NPD in therapeutic settings.

How Burning Man Failed

Daniel Pinchbeck’s Newsletter • 27 implied HN points • 29 Aug 23
🎭️ Culture Festivals Psychedelics Art Society Capitalism
  1. The Burning Man festival has shifted from its original vision and become more focused on wealth and status, losing its self-parody and social critique.
  2. Burning Man now reflects a culture of hollow hedonism and narcissism, with art and experiences tailored for Instagram and wealthy attendees.
  3. The lack of a meaningful critique on societal issues within Burning Man and the psychedelic renaissance highlights a need for collective action and political activism.

Why I'm Big on Psychedelics Integrated Therapy

Kushal’s Substack • 1 HN point • 08 Jul 24
🏥 Health & Wellness Psychedelics Therapy Mental health Healing Trauma
  1. Psychedelics integrated therapy can potentially cure many mental health problems if used correctly.
  2. Therapies like DBT help rewire the brain for conditions like BPD, but it can be challenging and time-consuming.
  3. Psychedelics, breathing techniques, and hypnosis can break down old thought patterns, making it easier to form new, healthier habits.

Ego Death by Any Other Name

Superb Owl • 4 HN points • 28 Jan 24
🏥 Health & Wellness Phenomenology Consciousness Meditation Psychedelics
  1. Experiencing ego death can involve shifts in perception and a dissolution of the sense of self.
  2. During ego death, one may experience proprioceptive distortions, spatial distortions, and immersion in sensations, leading to a sense of losing track of reality.
  3. De-reification plays a role in ego death, where concepts become fuzzy, reality is questioned, and a sense of self dissolves into the surroundings.