The hottest Immune System Substack posts right now

And their main takeaways
Category
Top Health & Wellness Topics
Your Local Epidemiologist β€’ 1694 implied HN points β€’ 21 Jan 26
  1. Getting the basics right matters most: aim for about 7+ hours of sleep, keep indoor air comfortably humid, and eat a nutrient- and fiber-rich diet to support immune function and reduce inflammation.
  2. Supplements are not magic β€” vitamin D helps mainly if you’re deficient, zinc may slightly shorten colds if started early, and megadosing or unregulated products can be harmful or ineffective.
  3. Practical home measures can help symptoms: nasal saline and clean humidifiers ease congestion and may limit spread, while trendy practices like cold plunges have mixed evidence and aren’t proven immune boosters.
Igor’s Newsletter β€’ 12618 implied HN points β€’ 21 Jan 24
  1. IgG4 antibodies caused by mRNA technology may lead to immune tolerance and reduced ability to fight infections.
  2. A study showed that mRNA vaccines resulted in much higher IgG4 levels compared to Novavax, indicating a dysfunctional immune response.
  3. The use of mRNA technology in vaccines has been linked to a faulty immune response, potentially worsening the pandemic.
Harnessing the Power of Nutrients β€’ 2256 implied HN points β€’ 23 Jan 24
  1. If you're still coughing after two weeks, the virus is likely gone, and there are simple changes you can make to help your body recover.
  2. Consider if your lingering cough is due to underlying conditions like asthma or long-COVID and seek appropriate help if needed.
  3. Optimizing the rhythm of immune defense can help you recover from sickness faster and get rid of a lingering cough.
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LIL Science β€’ 1277 implied HN points β€’ 03 Dec 23
  1. The concept of 'Immunity Debt' is a dangerous and misleading idea that lacks scientific evidence.
  2. Exposure to pathogens does not weaken the immune system but can lead to severe illness in immunocompromised individuals.
  3. Post-COVID-19 immune system dysfunction can have serious consequences like increased rates of cancer and autoimmune diseases.
LIL Science β€’ 943 implied HN points β€’ 24 Dec 23
  1. COVID-19 affects people differently, with factors like age, comorbidities, and exposure to the virus playing a role
  2. Genetics, such as blood type and HLA genotype, can impact susceptibility to severe COVID-19
  3. Research is ongoing to uncover genetic factors that influence COVID-19 severity, but prevention through vaccination, masks, and distancing remains key
Are You Okay? β€’ 519 implied HN points β€’ 23 Feb 24
  1. Alcohol is likely not good for our gut health and microbiome, which impacts various aspects of our health including immune system.
  2. New COVID guidelines have evolved, suggesting reduced isolation periods, which raises questions and concerns about effective safety measures.
  3. It's important to rethink alcohol consumption for better sleep, mood, weight control, and overall gut health, as excessive drinking can impact many health factors.
Microanimism β€’ 159 implied HN points β€’ 06 Jun 24
  1. Teeth can be intriguing and complex, with a unique texture and sensation that changes over time.
  2. Neglecting dental hygiene can lead to curious observations about plaque growth and mouth bacteria.
  3. The body's physiological responses, like immune reactions, can be both fascinating and uncomfortable to experience.
Harnessing the Power of Nutrients β€’ 1158 implied HN points β€’ 31 Jan 23
  1. The concept of a Fasting-Feeding Reset involves stacking supplements to optimize both fasting and feeding states for tissue health.
  2. Fasting is not suitable for everyone, especially pregnant/lactating women, children, or those with certain medical conditions.
  3. The fasting-feeding reset approach aims to clean up damaged tissue during fasting and rebuild healthy tissue during feeding for immune system improvements.
LIL Science β€’ 628 implied HN points β€’ 07 Sep 23
  1. Public comments about Sars-CoV-2 Fall 2023 Updated Booster must be submitted by September 8th, 2023, 11:59 EST.
  2. To submit a public comment, go to the CDC website, find the Public Comments tab, follow the link to the Federal eRulemaking Portal, and search by docket number CDC-2023-0060.
  3. Advocates believe the booster should be widely available due to limited protection from existing vaccines, risks of reinfection, and potential long-term health impacts.
Are You Okay? β€’ 499 implied HN points β€’ 22 Sep 23
  1. Individuals may receive conflicting advice on COVID boosters due to factors like age, health conditions, and immunity status. Consult with a healthcare provider to assess personal risk and benefits.
  2. Protection against severe COVID relies on T cells activated by past vaccines or infections, even if it has been a while since the last shot. Booster shots are especially beneficial for high-risk groups.
  3. Long-lasting symptoms like voice changes post-COVID recovery may occur. Always seek medical advice for persistent symptoms to determine if they are temporary or need further evaluation.
Β‘Do Not Panic! β€’ 432 implied HN points β€’ 21 Jun 23
  1. Sexually transmitted infections have spiked to generational highs in recent years globally.
  2. The weakening of population immunity due to mass COVID infections is a likely cause for the rise in STIs.
  3. Environmental toxins and pollution, including air pollution, are damaging sperm counts and threatening reproductive health.
Harnessing the Power of Nutrients β€’ 918 implied HN points β€’ 14 Nov 22
  1. Long-COVID, also known as post-acute sequelae of COVID-19, can present with a variety of symptoms that persist beyond the acute infection phase, with fatigue and breathing difficulties being common.
  2. Risk factors for developing long-COVID include the severity of the initial COVID illness and being female. Female sex is a consistent risk factor, possibly due to survivorship bias.
  3. The three main hypotheses to explain long-COVID are microclots, persistent antigen, and immune dysfunction. These factors may contribute to lingering symptoms and complications in long-COVID patients.
Are You Okay? β€’ 279 implied HN points β€’ 25 Aug 23
  1. Do not worry about taking over-the-counter medications like Ibuprofen for common vaccine side effects; they do not significantly affect vaccine effectiveness.
  2. It is possible for individuals to contract Covid, flu, and RSV at the same time; the severity of the illness can vary depending on the individual's health condition.
  3. Consult with your doctor if you are taking immunosuppressants while considering getting a vaccine; adjustments may be needed to ensure vaccine efficacy.
eugyppius: a plague chronicle β€’ 177 implied HN points β€’ 06 Mar 24
  1. A man from Magdeburg received 217 Covid vaccine jabs over 29 months, showing that achieving high antibody levels can prevent infection, with no negative health effects reported by researchers.
  2. The man's peculiar vaccination pattern raised questions about the investigation, incomplete jab data, and the feasibility of receiving so many doses without detection.
  3. The bizarre story prompts speculation about potential conspiracy theories regarding the man's extensive vaccination history and the challenges of verifying such a unique case.
Holodoxa β€’ 2 HN points β€’ 03 Jul 24
  1. The immune system has key components like T cells which play a crucial role in fighting cancer by harnessing latent immunity.
  2. Researchers like James Allison and Tasuku Honjo have made significant contributions in understanding how cancer evades the immune system and how immune checkpoints like CTLA-4 and PD-1 can be targeted to enhance immune response against cancer.
  3. Cellular immunotherapy, particularly immune checkpoint inhibitors targeting PD-(L)1, has shown great potential in treating various cancers, with some patients showing long-term remissions and ongoing innovative developments in this field.
Axial β€’ 22 implied HN points β€’ 03 Mar 24
  1. Combining antibodies directed at different viral targets helps neutralize infections like hepatitis B virus and RSV more effectively.
  2. Serial passage of virally infected cells during preclinical development helps ensure the continued efficacy of antibody combinations.
  3. Engineering antibodies through genetic manipulation can enhance effector functions and improve target specificity, increasing their efficacy in fighting infections.
Outspoken with Dr Naomi Wolf β€’ 14 implied HN points β€’ 26 Jun 23
  1. The author shares her experience in the hospital after undergoing an appendectomy and battling an acute infection.
  2. The author reflects on the limitations of modern hospitals compared to 19th-century healing practices like access to healing gardens and uninterrupted sleep.
  3. The author expresses gratitude for her immune system and the lessons she learned from 'dissident doctors' about personal responsibility for immune health.
Joshua Gans' Newsletter β€’ 19 implied HN points β€’ 13 Nov 20
  1. Vaccination aims to protect individuals from the virus as well as stop them from spreading it to others - this distinction is important for determining who should be vaccinated first.
  2. The effectiveness of a vaccine in preventing infection and transmission varies - some vaccines offer indirect protection by blocking transmission between people.
  3. It's crucial to understand how vaccines impact the spread of disease in communities - monitoring vaccinated individuals for contagiousness is essential, especially with imperfect vaccines.