The hottest Brain preservation Substack posts right now

The brain's sensory information changes over time through representational drift
Memory formation and synaptic strength may have similarities in dendritic spine volumes
New methods are helping to identify and understand specific cell types in the brain

Study on extrasynaptic neural signaling in C. elegans challenges the idea that synapses are the sole key to brain information content.
Neuropeptide signaling plays a crucial role in behaviors like aggression in mice, emphasizing its significance beyond nematodes.
Mouse amygdala study highlights differences in brain cell activity during memory formation and recall, shedding light on the complex processes of memory.

The goal of brain preservation is to protect and store information from a person's brain for potential future revival.
Structural metrics, like intact cell membrane morphology, are crucial for evaluating brain preservation methods.
Connectome traceability by contemporary electron microscopy sets a high standard for brain preservation, but intact cell morphology on light microscopy can be a reasonable proxy.

Brain rhythms are natural patterns of neural activity measured using EEG or other neuroimaging techniques.
Preserving brain structure could potentially help recapitulate brain rhythms, but uncertainties remain about the link between structure and function.
Research on cryopreserving brain cells responsible for brain rhythms is valuable, but demonstrating memory retention post-preservation requires more than just measuring electrophysiological signals.

New study in neurobiology identifies different types of inhibitory neurons based on connectivity data
Research on the C. elegans nervous system during unique developmental stages highlights connectomic differences
Study on Drosophila visual system shows synaptic partner selection influenced by cell adhesion molecule expression patterns

Get a weekly roundup of the best Substack posts, by hacker news affinity:

Mutual autopsy societies in the late 1800s preserved and studied members' brains to advance science.
Brain preservation methods involved using different fixatives like alcohol and formaldehyde as the science evolved.
Members of these societies faced challenges like family resistance and scandal, which offer lessons for today.