The hottest Medical Research Substack posts right now

And their main takeaways
Top Health Politics Topics
Ground Truths β€’ 10104 implied HN points β€’ 28 Feb 24
  1. Two new studies show cognitive deficits after Covid in large populations, with impacts on memory, executive function, and reasoning.
  2. The cognitive decline from Long Covid can range from 3 to 9 IQ points, showing significant impact even after symptoms resolve.
  3. Research indicates that cognitive decline from Covid can persist for up to 3 years, emphasizing the long-term effects of the virus on brain function.
Erin In The Morning β€’ 10161 implied HN points β€’ 02 Feb 24
  1. The article by Pamela Paul in The New York Times relies on debunked information about transgender care and detransitioning.
  2. Claims about rapid onset gender dysphoria and social contagion in the article are not supported by reliable research or credible sources.
  3. The assertion that a significant percentage of transgender individuals detransition or desist is based on outdated and flawed studies, contradicting more recent research findings.
Igor’s Newsletter β€’ 12618 implied HN points β€’ 21 Jan 24
  1. IgG4 antibodies caused by mRNA technology may lead to immune tolerance and reduced ability to fight infections.
  2. A study showed that mRNA vaccines resulted in much higher IgG4 levels compared to Novavax, indicating a dysfunctional immune response.
  3. The use of mRNA technology in vaccines has been linked to a faulty immune response, potentially worsening the pandemic.
RESCUE with Michael Capuzzo β€’ 5267 implied HN points β€’ 03 Feb 24
  1. Paul Mann, diagnosed with stage four cancer, used ivermectin along with traditional treatments and supplements to achieve remission.
  2. A study led by Dr. Kathleen Ruddy aims to determine if repurposed drugs like ivermectin can improve survival rates for different types of cancer.
  3. The study, titled 'God of Pi', emphasizes systematic exploration of repurposed drugs in cancer treatment, focusing on patient safety and research integrity.
Are You Okay? β€’ 359 implied HN points β€’ 29 Mar 24
  1. Measles is difficult to contain due to the anti-vax movement and asymptomatic spread. Symptoms can include cough, runny nose, pink eye, fever, and a rash spreading across the body.
  2. Vaccination is the most effective way to prevent measles and provides lifelong protection. It is recommended for adults without a history of measles.
  3. Taking vitamin B12 supplements may be necessary for individuals with low levels, especially if caused by medications like Prilosec; however, unnecessary vitamin supplementation should be approached with caution.
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2nd Smartest Guy in the World β€’ 3400 implied HN points β€’ 19 Jan 24
  1. American Cancer Society projects over 2 million cancer diagnoses for the first time in 2024
  2. Younger individuals are increasingly being diagnosed with colorectal cancer
  3. Discussion on alternative drugs like Ivermectin and Fenbendazole for potential cancer treatment
Alexander News Network -Dr. Paul Elias Alexander's substack β€’ 2004 implied HN points β€’ 29 Jan 24
  1. Urgent call to rewrite the abstract of a paper on Cureus due to concerns about the language used and safety of mRNA technology.
  2. Questioning the necessity of safety studies for vaccines that are already known to be harmful.
  3. Critique of 'modified mRNA' technology and urging for clear, direct communication about the risks.
Parrhesia β€’ 494 implied HN points β€’ 09 Mar 24
  1. Several scientists and professional organizations criticize polygenic embryo screening for polygenic disorders due to concerns like lack of validation and utility.
  2. The article argues that the recommendation against polygenic embryo screening is flawed because it doesn't compare the method to other acceptable alternatives like selection based on embryo morphology.
  3. The authors suggest that the critique against polygenic embryo screening lacks consideration of the ethical implications and does not provide a comprehensive cost-benefit analysis.
Ground Truths β€’ 7742 implied HN points β€’ 24 Sep 23
  1. The expanding GLP-1 drug family shows potential for treating obesity with new triple agonist drugs.
  2. Clinical trials with G-agonists reveal reductions in major cardiovascular events and heart failure symptoms.
  3. GLP-1 drugs have shown promise in treating early type 1 diabetes, cognitive function, alcohol use disorder, and more.
Alexander News Network -Dr. Paul Elias Alexander's substack β€’ 727 implied HN points β€’ 10 Feb 24
  1. Questions are raised on how medical professionals allowed the approval of untested mRNA technology for Covid vaccines, prompting a need to investigate incentives and motives of key figures.
  2. Concerns are voiced about the silence regarding potential risks and long-term effects of mRNA vaccines communicated by medical doctors and scientists like Malone, Bourla, Weissman, and Kariko.
  3. Criticism is directed towards media outlets and organizations for not holding key players accountable and failing to ask important questions about the safety and efficacy of Covid vaccines.
Rory’s Always On Newsletter β€’ 609 implied HN points β€’ 31 Jan 24
  1. Signing up for 'Our Future Health' involves sharing medical data and participating in research.
  2. The process includes completing a detailed health questionnaire and undergoing tests at a clinic.
  3. Volunteers have the option to participate in various aspects of the program and a strong emphasis is placed on the voluntary nature of involvement.
eugyppius: a plague chronicle β€’ 177 implied HN points β€’ 06 Mar 24
  1. A man from Magdeburg received 217 Covid vaccine jabs over 29 months, showing that achieving high antibody levels can prevent infection, with no negative health effects reported by researchers.
  2. The man's peculiar vaccination pattern raised questions about the investigation, incomplete jab data, and the feasibility of receiving so many doses without detection.
  3. The bizarre story prompts speculation about potential conspiracy theories regarding the man's extensive vaccination history and the challenges of verifying such a unique case.
Common Sense with Bari Weiss β€’ 204 implied HN points β€’ 22 Feb 24
  1. Transparency of raw data in medical research is crucial to uncovering fraud, as many papers only present summaries hiding potential malpractice.
  2. In medical research, the data presented in scientific papers is akin to a curated dating profile, showing only a portion of the actual work done.
  3. Calls for greater transparency, such as making all raw data available when publishing medical research, are crucial to combat fraud and encourage accountability in the field.
News from Those Nerdy Girls β€’ 373 implied HN points β€’ 23 Jan 24
  1. Puberty blockers are reversible and help improve the mental health of trans youth while reducing the need for future surgeries.
  2. Using puberty blockers gives trans youth time to explore interventions and prevents irreversible physical changes.
  3. Research shows that puberty blockers are safe and beneficial for trans youth, improving well-being and decreasing mental health risks.
Β‘Do Not Panic! β€’ 904 implied HN points β€’ 21 Oct 23
  1. Junk science influenced a country's health policy and denied benefits to chronically ill people.
  2. Medical professionals can be influenced by social and political ideologies, impacting patient care.
  3. Persistent advocacy by sufferers can challenge harmful treatment recommendations and promote understanding of medical conditions.
Singal-Minded β€’ 1623 implied HN points β€’ 15 Jun 23
  1. The American Medical Association and Endocrine Society's statement on youth gender medicine is filled with misinformation and non sequiturs.
  2. There are concerns about the lack of rigorous research supporting the use of puberty blockers in youth gender medicine.
  3. Major medical organizations have been criticized for spreading misinformation on sensitive and politicized topics, leading to questions about their trustworthiness.
What the Health?! β€’ 78 implied HN points β€’ 08 Feb 24
  1. A VC fund bought a hospital, Elon Musk implanted brain chips in humans, and we are consuming millions of microplastics.
  2. Important updates in the health tech and innovation space, including funding reports, startup news, and noteworthy events.
  3. Exciting developments such as breakthroughs in diabetes treatment, presence of microplastics in protein sources, and advancements in cancer detection through blood tests.
Asimov Press β€’ 96 implied HN points β€’ 21 Jan 24
  1. Human challenge trials have been used for centuries to deliberately infect individuals with pathogens for research purposes, such as testing vaccines and treatments.
  2. The rising popularity of challenge trials can be attributed to ethical reforms, development of solid challenge models, and the ability to safely and effectively test vaccines for various diseases.
  3. Challenge trials have drawbacks, including recruitment challenges, underpayment of participants, and difficulty in quantifying overall impact.
The Rotten Apple β€’ 21 implied HN points β€’ 11 Mar 24
  1. Downloadable back issues are available for readers to catch up on past content.
  2. Improper handwashing and contaminated food led to a man in the US developing tapeworm larvae in his brain, highlighting the importance of food safety practices.
  3. The chocolate supply chain is facing a crisis due to rising cocoa prices caused by global supply pressures from climate change, impacting chocolate production and potentially leading to product frauds.
Welcome to Absurdistan β€’ 1061 implied HN points β€’ 23 Apr 23
  1. Some scientists face challenges when they go against the consensus in the medical field.
  2. Alternative medicine and nutritional focus might offer solutions in health issues.
  3. There are individuals and authors working to expose the darker sides of the pharmaceutical and medical industries.
Injecting Freedom β€’ 91 implied HN points β€’ 11 Jan 24
  1. Federal Judge orders CDC to release 7.8 million V-safe free-text entries for public access.
  2. The decision aims to promote transparency, trust, and accountability in government health data.
  3. Releasing the V-safe data is crucial for independent research and evaluating the safety and efficacy of COVID-19 vaccines.
Steve Kirsch's newsletter β€’ 9 implied HN points β€’ 16 Mar 24
  1. A recent Thailand clinical trial showed 100% effectiveness in preventing COVID hospitalizations with a 2-drug combination, in contrast to the 37.5% hospitalization rate with standard care.
  2. The early treatment combination of fluvoxamine and another drug displayed clear benefits in preventing hospitalizations and reducing serious adverse events, unlike the COVID vaccines.
  3. Despite strong evidence and successful outcomes of multi-drug treatments since early 2020, health authorities and organizations like CDC, FDA, and WHO continue to overlook and ignore these effective treatment options.
The Skeptical Cardiologist β€’ 393 implied HN points β€’ 01 Jul 23
  1. A recent study found no increase in cardiovascular risk with testosterone therapy for men with low T levels.
  2. Make sure to confirm low T levels before starting testosterone therapy.
  3. Weight loss and exercise can help alleviate symptoms related to low T without the use of testosterone therapy.
Experimental Fat Loss β€’ 134 implied HN points β€’ 04 Nov 23
  1. Cutting out seed oils can lead to improved skin health and reduced sunburn sensitivity.
  2. Seed oils can easily oxidize and negatively impact cell membranes, potentially causing health issues.
  3. The body can regenerate various cells impacted by seed oils within days to years, leading to potential health improvements over time.
The Good Science Project β€’ 18 implied HN points β€’ 21 Feb 24
  1. The debate around NIH's march-in rights intersects with concerns over potentially overpriced pharmaceuticals developed with NIH funding.
  2. Empirical evidence suggests that very few drugs could be subject to NIH's march-in rights due to limited NIH funding directly impacting drug development.
  3. The application of march-in rights under Bayh-Dole is complex legally and practically, with challenges such as potential lawsuits over arbitrary interpretation and limited impact on drug pricing.
Silent Lunch, The David Zweig Newsletter β€’ 23 implied HN points β€’ 02 Feb 24
  1. States threw away millions of dollars worth of PPE that could have still been effective.
  2. Expiration dates on masks and gowns may not accurately reflect their actual effectiveness.
  3. Authority decisions on PPE disposal lack evidence-based analysis and contribute to public health policy concerns.
The Century of Biology β€’ 272 implied HN points β€’ 26 Mar 23
  1. Multiple important technological paradigms are converging in the life sciences, impacting life on various scales.
  2. Synthetic biology focuses on designing new genetic circuits to program cells for new tasks.
  3. Using a platform like CLASSIC, genetic circuits can be systematically tested to learn composition-to-function relationships.
Experimental Fat Loss β€’ 141 implied HN points β€’ 27 May 23
  1. Eating high protein might hinder fat loss on Keto/Carnivore diets; consider reducing protein intake.
  2. Popular Keto/Carnivore diets emphasize high protein, but excessive protein intake may not be suitable for everyone.
  3. Moderating protein intake and focusing on adequate fat consumption is essential for maintaining a balanced diet on Keto/Carnivore.