The hottest Health Substack posts right now

And their main takeaways
Category
Top Technology Topics

Protein Sequencing Companies In Review

ASeq Newsletter • 29 implied HN points • 02 Jul 25
🔬 Science Health
  1. Protein sequencing is harder than DNA sequencing because it involves single molecules and many different amino acids, making detection tricky.
  2. Despite the challenges, protein sequencing is often about counting the same sequences many times, which might ease some of the technical demands.
  3. With advancements like nanopore technology, the future of protein sequencing could become more practical and efficient for researchers.

Candidate profile: Bethany Mandel

Can We Still Govern? • 193 implied HN points • 21 Feb 24
🇺🇸 U.S. Politics Health
  1. Bethany Mandel is posing as a Democrat for a predominantly Democratic region, even though she identifies as a Republican and campaigns in an anti-woke, right-wing style.
  2. Mandel raises concerns about legal fees in the school district yet is actively suing the school while also suing teachers for blocking her on Twitter, showing a lack of consistency.
  3. Mandel, despite not having her children attend school, is critical toward public services, misunderstands the social contract, flip-flopped on vaccines during the pandemic, and lacks tolerance for views diverging from her own.

Headlines of Interest - Week of March 1st

Random Minds by Katherine Brodsky • 56 implied HN points • 01 Mar 25
📰 News Health
  1. China is telling its AI experts not to travel to the US due to fears of espionage. This shows a growing tension in international relations over technology.
  2. A new mRNA vaccine shows promise in treating pancreatic cancer, with early trials indicating a high percentage of patients cancer-free after a few years.
  3. Biohybrid robotics are emerging, combining living materials like fungi with machines to improve their abilities. This could lead to smart robots that are more aware of their environment.

Thanksgiving and Dr Maté

Splattern • 39 implied HN points • 24 Nov 23
🎭️ Culture Health
  1. The writer enjoyed a Thanksgiving run on a beautiful trail, appreciating nature in their home state.
  2. This year was special because the writer's entire immediate family got together for Thanksgiving, which hasn't happened in a long time.
  3. The gathering felt healing and fun, marking a positive change since the family's previous issues.
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Genetics can predict height, cancer risks, neuropsychiatric diseases and more — but not IQ?

Nucleus Genomics • 4 HN points • 11 Jul 24
🔬 Science Health
  1. Genetics can help us understand traits like height and disease risks, but predicting intelligence (IQ) is much more complex and not fully possible yet.
  2. Current genetic models can give partial insights about how genes may influence intelligence but cannot tell you your exact IQ.
  3. As technology improves, genetic predictions for traits, including intelligence, may get better, providing more useful information about how genetics interacts with environment.

ex150ish-4-sour-cream-lowish-protein-recarb

The Heart Attack Diet • 39 implied HN points • 23 Nov 23
🍲 Food & Drink Health
  1. The experiment with ex150ish-4-sour-cream-lowish-protein-recarb was successful with a weight loss of 2.5kg in roughly four weeks.
  2. Eating sour cream and crème fraîche seemed to work the same as double cream for the author.
  3. Switching from Mom Test to ex150ish was able to undo rapid weight gain from eating normally, providing a successful weight loss strategy.

Cheating at Evolution

Eat Shit and Prosper • 159 implied HN points • 01 Nov 22
🔬 Science Health
  1. Bacteria can share genes with each other quickly, helping them adapt and survive in their environment. This 'horizontal gene transfer' allows them to grab useful traits without the slow process of traditional evolution.
  2. Some animals eat feces to gain beneficial bacteria that help them digest tough foods and absorb nutrients. This behavior helps spread helpful microbes more quickly among their populations.
  3. Understanding how microbes influence our health could lead to new treatments for various diseases. Using healthy microbes from poop could potentially improve a person's well-being significantly.

Being Tired is a Choice

An Interpersonal Journal • 59 implied HN points • 19 May 23
🏥 Health & Wellness Health
  1. Feeling tired is often a choice we make, and we can find energy and inspiration by engaging in activities we love.
  2. Discipline and focus are key to overcoming challenges and achieving long-term goals.
  3. It's important to make conscious decisions about how we spend our time and prioritize activities that bring us fulfillment, even if it means sacrificing other less meaningful pursuits.

Forget Gene Therapy. Microbes are the Future of Medicine.

Eat Shit and Prosper • 159 implied HN points • 28 Oct 22
🔬 Science Health
  1. Microbes in our gut act like software, constantly changing and adapting, while our genes stay mostly fixed. This flexibility allows our bodies to optimize their functions more effectively.
  2. Unlike permanent changes in our DNA, mutations in microbes can lead to quick advantages without the risk of harmful outcomes. This means our body can benefit from favorable changes without damaging our core genetic makeup.
  3. Using microbes to adapt to different diets or conditions is faster and less risky than gene therapy. Microbes evolve quickly, making them a promising tool for improving health and dealing with diseases.

Fresh perspective with a new coach

Splattern • 19 implied HN points • 02 Mar 24
🎾 Sports Health
  1. Getting a new coach has brought fresh ideas and support. It's helpful to have someone experienced to guide and motivate you.
  2. Understanding your body and its responses is important. Talking to a coach can uncover issues like knee pain related to running habits.
  3. Having a supportive environment and people around you adds to the overall experience. Feeling appreciated by others can boost your spirits.

My TED Talk is now live

Sustainability by numbers • 241 implied HN points • 22 Sep 23
🔬 Science Health
  1. We can improve human wellbeing while tackling environmental problems together.
  2. Global progress has been made in reducing child mortality and extreme poverty.
  3. Transitioning to renewable energy sources, such as solar and wind power, is becoming more affordable and can help combat air pollution.

The Food Is Poison, The Lobbyists Know It

QTR’s Fringe Finance • 24 implied HN points • 11 Jul 25
🍲 Food & Drink Health
  1. Many foods we eat today are ultra-processed and full of harmful chemicals. These foods can make us sick rather than healthy.
  2. Ultra-processed foods can be addictive, similar to drugs, which makes it hard for people to stop eating them. They change how our brain works and influence our eating habits.
  3. The food industry and health system are connected in ways that may prioritize profit over our well-being. This often leaves people confused and unhealthy.

Summer 2025 Update

Kesav’s Lab • 16 implied HN points • 01 Sep 25
🕹 Technology Health
  1. Being in different environments like coffee shops or co-working spaces boosts my productivity. I find that I work better when I mix things up a bit.
  2. Attending events helps create chances for collaboration and opportunities. When I put myself out there, good things tend to happen.
  3. Austin has a great vibe for work-life balance. It's a relaxed place, while NYC feels fast-paced and intense, which can push me to be more productive.

Vlad's Rad

Diane Francis • 319 implied HN points • 02 Sep 21
🇺🇸 U.S. Politics Health
  1. The Havana Syndrome is a mysterious illness affecting U.S. diplomats and spies, with symptoms linked to strange sounds and neurological damage. This has prompted an investigation by a CIA task force.
  2. Officials suspect that advanced microwave technology may be involved, but there’s still no clear evidence of how it works or who is responsible. This raises concerns about hybrid warfare tactics.
  3. Past incidents, like the attacks on diplomats in Cuba and China, indicate a pattern of targeting U.S. officials, leading experts to believe the attacks could qualify as acts of war.

Lỗ hổng của Sổ sức khỏe điện tử

Thái | Hacker | Kỹ sư tin tặc • 259 implied HN points • 13 Oct 21
🕹 Technology Health
  1. The electronic health record system had several security vulnerabilities like default passwords, IDOR, HQL Injection, and path traversal.
  2. The system's security issues were a cause for disappointment as it seemed lack of responsible security assessment teams had overlooked these basic vulnerabilities.
  3. There were common security oversights like unauthenticated API endpoints, SQL injection vulnerabilities, path traversal vulnerabilities, and use of default passwords.

Announcing my new podcast: The Studies Show

Science Fictions • 248 implied HN points • 25 Jul 23
🎙 Podcasts Health
  1. The podcast "The Studies Show" discusses controversial scientific topics weekly with an English/Scottish accent combo.
  2. Episodes include topics like Aspartame, Psychedelics, Breastfeeding, and Vaping, among others.
  3. Listeners can subscribe for free on the podcast's Substack page and access episodes on various platforms like Apple Podcasts and Spotify.

July Subscriber AMA Answers

Weight and Healthcare • 119 implied HN points • 05 Aug 22
🏥 Health & Wellness Health
  1. The post shares July's Subscriber AMA answers on weightandhealthcare.substack.com.
  2. The author apologizes for being late due to their dog's health issues, but assures that the dog will be fine.
  3. There's a focus on the Health At Every Size (HAES) space for anti-diet approaches in the content.

What's new in biology: summer 2025

The Works in Progress Newsletter • 22 implied HN points • 09 Jul 25
🔬 Science Health
  1. A personalized gene therapy using CRISPR has helped a baby with a rare genetic disease, allowing him to eat more protein without harmful effects. This shows how quickly treatments can be developed for urgent medical needs.
  2. New RSV vaccines are significantly reducing hospitalizations for infants in the US, proving to be effective in protecting young babies from severe respiratory infections. If more infants got vaccinated, there would be even fewer hospital visits.
  3. A new cholesterol drug, obicetrapib, is showing promise in lowering LDL levels for heart disease patients, even those already on maximum doses of statins. It seems to have fewer side effects, making it a good option for many.

Mom Test: Rebound?

The Heart Attack Diet • 39 implied HN points • 21 Oct 23
🏥 Health & Wellness Health
  1. The author discusses weight fluctuations and possible reasons for a sudden weight drop after experiencing COVID.
  2. The author mentions feeling lethargic and sad after going through a mild case of COVID.
  3. In uncertain situations, the author considers taking a cautious approach and 'dithering' until the situation becomes clearer.

The Future Is Plastics, Benjamin

God's Spies by Thomas Neuburger • 65 implied HN points • 06 Dec 24
🌞 Climate & Environment Health
  1. Microplastics are everywhere in our bodies. They are found in blood, organs, and even in breast milk, but we still don't know how much damage they can cause.
  2. Big oil companies are pushing to make even more plastics. They see profit in plastic production despite the environmental harm it causes.
  3. Bottled water may contain a lot of small plastic pieces. Some scientists are now drinking less bottled water because of the high levels of micro and nanoplastics found in it.

BREAKING NEWS: Prof. Dr. Bob Wachter, Deranged UCSF Dept. of Medicine Chair, Finally Caught Covid, Fainted in Shower, Is Now Recovering at Home

eugyppius: a plague chronicle • 239 implied HN points • 15 Jul 23
📰 News Health
  1. Prof. Dr. Bob Wachter, a noted figure in Covid Chronicles, caught Covid despite precautions.
  2. Wachter, a double vaccinee, got infected after his last shot and fainted in the shower due to Covid-induced dehydration.
  3. His experience led him to ponder on hospitalizations 'with Covid' versus 'for Covid.'

Fragments #2

aproposofnothing • 39 implied HN points • 16 Jun 23
💾 History Health
  1. Turning 30 can signify a new chapter of growth and purpose in life.
  2. In ancient Greece, music and study were important cultural practices before the age of 30.
  3. Plato's ideas on leadership, military training, and noble lies still hold relevance today.

I just bought a pillbox

Inside Game • 39 implied HN points • 08 Jun 23
🏥 Health & Wellness Health
  1. The author talks about how they've always been old at heart and prefer quieter, simpler activities over partying.
  2. The purchase of a pillbox was driven by the author's desire to systemize and streamline their daily habits.
  3. By investing time and effort into setting up efficient systems, the author finds that achieving goals becomes easier and more sustainable in the long run.

Links for April

Bullfish Hole • 39 implied HN points • 14 Apr 23
🎭️ Culture Health
  1. There have been historical balloon riots that turned violent when spectators attacked the balloons or balloonists.
  2. Criminals are now using AI technology to mimic voices and scam people for money, posing new challenges for security.
  3. In some regions, like Ghana, witch camps still exist where accused witches seek refuge from being lynched.

Compilation Post #3

Extropic Thoughts • 39 implied HN points • 15 Apr 23
🔬 Science Health
  1. Child mortality rates have drastically decreased over centuries, signifying significant progress in global healthcare.
  2. America's GDP and economic dominance have continued to grow, especially when compared to its developed peers like in 1990.
  3. AI advancements like ChatGPT's 'iPhone moment' and BloombergGPT are reshaping industries with their capabilities.

A Trio of Environmental Articles For Your Sunday/Monday Reads

crimeandpunishment • 39 implied HN points • 03 Apr 23
🌞 Climate & Environment Health
  1. Politics and our natural world are interconnected; we need to reduce fossil fuel use and harmful chemicals to protect our environment and ourselves.
  2. Deforestation can lead to disease outbreaks by creating close contact zones between humans and wild animals.
  3. Climate change not only impacts physical health but can also have negative effects on mental health, leading to anxiety, depression, and other mental health issues.

These politically enthusiastic supplement fans do not exist

Conspirador Norteño • 44 implied HN points • 22 Feb 25
🇺🇸 U.S. Politics Health
  1. Some social media accounts are fake and use AI-generated faces to push products, like weight loss supplements. They create the impression of being real people to promote their ads.
  2. These accounts often mimic authentic political personas, but they show signs of being inauthentic, like having repeated text or the same profile images. This raises questions about the trustworthiness of the content shared.
  3. A website linked to these ads uses fake reviews from AI-generated profiles, making it seem like people are satisfied customers when they're not real. This highlights the need to be careful about schemes like these online.

Love isn’t always on time (I'm sick)

Sex and the State • 16 implied HN points • 02 Aug 25
🎭️ Culture Health
  1. Getting sick can happen to anyone, and it's important to take time to heal without feeling bad about it.
  2. Even when you're feeling under the weather, you can still enjoy things like TV shows or movies to help pass the time.
  3. Love and support are always important, even if things don’t go as planned or take longer than expected.

Circling the LNT Wagons

Gordian Knot News • 205 implied HN points • 26 Aug 23
🔬 Science Health
  1. The Linear No-Threshold theory (LNT) in radiation protection is being challenged due to its assumption that harm is solely based on cumulative dose, ignoring dose rate and repair ability.
  2. Studies on nuclear workers show limitations as they only focus on cumulative doses and do not consider variations in dose rates, which are crucial for understanding radiation harm.
  3. The INWORKS study, which supports LNT, has faced criticism for excluding certain data, lacking dose rate information, and not making data available, raising questions about its scientific validity.

The Ultima Genomics/Olink BioBank Deal

ASeq Newsletter • 51 implied HN points • 11 Jan 25
🔬 Science Health
  1. Ultima Genomics has won a significant project with the UK Biobank to analyze 700,000 samples. This partnership is a major step for them in the field of proteomics.
  2. Despite the project size, Ultima is expected to generate only $10 million to $20 million in revenue. This highlights the tough financial realities in the biotech industry.
  3. To stay viable, Ultima needs to secure more large projects, as its costs are high. Achieving the necessary volume of work may be challenging given the current economic situation.

LLMs Will be Like Ozempic for Golf

House of Strauss • 16 implied HN points • 04 Aug 25
🎾 Sports Health
  1. Using LLMs can help golfers improve their skills quickly by analyzing data and giving specific feedback. This is similar to how some people lose weight with certain medications.
  2. The combination of robot assistance and personal instruction can enhance learning in sports like golf, which relies on precise techniques.
  3. There is potential for widespread improvement in golf skills, which might change the sport and how people engage with it.

Field Notes: Bangkok

Terra Nullius, by Ned Donovan • 54 implied HN points • 09 Dec 24
🏝 Travel Health
  1. Bangkok is seeing fewer babies and a rise in pet ownership. Many young families are having fewer children due to costs and changing social values.
  2. It's hard to find trash bins in Bangkok, making it tricky to throw things away while exploring the city. This small issue can be surprisingly annoying while walking around.
  3. Traffic in Bangkok can be really bad, especially during rush hours. It's better to plan your travels outside of these peak times to avoid long waits.

Little Treats #4

Autoscriptorium • 39 implied HN points • 17 Mar 23
🪞 Fashion & Beauty Health
  1. Contentment comes from pushing ourselves to the utmost in many aspects of life, and requires a balance of self-imposition and external influences.
  2. Little treats can bring joy, like sushi grade salmon for quick meals, investing in quality makeup brushes, and enjoying peaceful Palestrina music.
  3. Simple pleasures are important, such as finding the perfect lipstick, savoring green juice, and engaging in specific exercises like sprints and heavy hip thrusts for inner peace.