The hottest Mitochondria Substack posts right now

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The Mitochondrial Nutrient Missing From Every Supplement

Harnessing the Power of Nutrients • 2536 implied HN points • 30 Jan 24
🏥 Health & Wellness Nutrition Supplements Mitochondria Vitamins
  1. There's a key nutrient, MK-4, crucial for mitochondrial health that is often missing from many supplements.
  2. MK-4 and CoQ10 have similar structures and roles in the respiratory chain, but play distinct functions and cannot substitute each other.
  3. For optimal mitochondrial support, it's recommended to include MK-4 alongside CoQ10 in a ratio of around 1 microgram of MK-4 for every 1 milligram of CoQ10.

Thiamin Supplements: Not For Everyone

Harnessing the Power of Nutrients • 1697 implied HN points • 19 Feb 24
🏥 Health & Wellness Nutrition Supplementation Metabolism Mitochondria Toxicity
  1. Thiamin is crucial for various functions like stable blood glucose, calmness, tissue health, detoxification, and athletic performance.
  2. Thiamin deficiency can lead to issues such as mitochondrial dysfunction, nerve problems, and eyesight deterioration.
  3. Excessive thiamin supplementation may cause adverse effects and stress on metabolic pathways, so it's important to be mindful of when to supplement thiamin and when to stop.

Is Vitamin C Destroying Your Mitochondria?

Harnessing the Power of Nutrients • 1617 implied HN points • 17 Feb 24
🏥 Health & Wellness Nutrition Supplements Mitochondria Oxidative stress Metabolism
  1. High doses of Vitamin C can inhibit CoQ10 synthesis and decrease copper status, affecting mitochondrial function.
  2. Excessive Vitamin C intake can lead to the generation of oxalate, a mitochondrial toxin, causing potential mitochondrial damage.
  3. While high doses of Vitamin C can have benefits in specific cases, for general use, it's safer to stick to doses from a Vitamin C-rich diet.

Linoleic Acid and Mitochondrial Dysfunction

The Heart Attack Diet • 219 implied HN points • 24 Apr 24
🏥 Health & Wellness Nutrition Mitochondria
  1. Hypothyroidism can present without abnormal hormone levels and might lead to conditions like Chronic Fatigue Syndrome, Fibromyalgia, or Major Depression.
  2. Mitochondrial dysfunction, like in Chronic Fatigue Syndrome, can be linked to low levels of thyroid hormones which normally stimulate mitochondria.
  3. Linoleic acid in the inner mitochondrial membrane plays a crucial role in providing stability through polymerization, despite being an unstable and rare substance.

Questions on statins versus sulfur, glutathione intolerance, plasma zinc

Harnessing the Power of Nutrients • 499 implied HN points • 24 Oct 22
🏥 Health & Wellness Nutrition Supplementation Glutathione Mitochondria
  1. Statins may reduce heart disease risk, but their benefits could be influenced by conflicts of interest; getting sulfur from protein sources may help lower cholesterol.
  2. Glutathione intolerance could stem from various amino acids or gut microbial metabolites; there are tests available for identifying the cause.
  3. Plasma zinc is a key marker of zinc status; factors like inflammation and stress can affect its levels, and symptoms should guide zinc supplementation decisions.
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