The hottest Supplements Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

Got Sperm? Prenatal Gummies for Men

Snaxshot • 519 implied HN points • 22 Oct 24
🍲 Food & Drink Supplements
  1. There's a new trend of 'prenatal gummies' designed for men, which aim to support sperm health.
  2. The grocery market is evolving, with a rise in expensive, trendy food options, especially among younger shoppers.
  3. The author is actively sharing insights and news, suggesting they are engaged in talks and discussions around current food trends.

ex150nosauce+ACV-4 review: Lost 8lbs, New All Time Low

Experimental Fat Loss • 169 implied HN points • 16 Mar 26
🏥 Health & Wellness Supplements
  1. The nosauce + apple cider vinegar protocol produced steady, mostly linear fat loss and reached a new all-time low, with an initial rapid drop in water weight followed by consistent fat loss.
  2. Because the regimen reduces heavy cream, daily protein can fall below about 40 g and trigger protein‑leverage hunger; a single day of increased meat intake resolved the hunger without derailing progress.
  3. A planned tweak is to run two 14‑day bouts separated by a one‑day refeed to capture faster early losses and better manage occasional protein hunger.

How to strengthen your immune system

Your Local Epidemiologist • 1694 implied HN points • 21 Jan 26
🏥 Health & Wellness Supplements
  1. Getting the basics right matters most: aim for about 7+ hours of sleep, keep indoor air comfortably humid, and eat a nutrient- and fiber-rich diet to support immune function and reduce inflammation.
  2. Supplements are not magic — vitamin D helps mainly if you’re deficient, zinc may slightly shorten colds if started early, and megadosing or unregulated products can be harmful or ineffective.
  3. Practical home measures can help symptoms: nasal saline and clean humidifiers ease congestion and may limit spread, while trendy practices like cold plunges have mixed evidence and aren’t proven immune boosters.

The Death-Strewn Backstory of Big Supplement

The Vajenda • 6151 implied HN points • 18 Jan 24
🏥 Health & Wellness Supplements
  1. Supplements in the United States have a history of being unregulated and potentially dangerous due to a lack of oversight and testing.
  2. The Dietary Supplement Health and Education Act of 1994 removed regulations, allowing for the sale of supplements without proof of safety or efficacy.
  3. Buying supplements is like buying gas from a guy on the side of the road - there's little to no assurance of what you're actually getting or its effects on your health.

This Is What Causes B6 "Toxicity"

Harnessing the Power of Nutrients • 1977 implied HN points • 21 May 24
🏥 Health & Wellness Supplements
  1. Vitamin B6 is essential for various bodily functions like preventing low blood glucose, maintaining muscle health, and improving skin condition.
  2. Estrogen and inflammation can increase the body's need for B6, so monitoring intake is crucial, especially for individuals with high-protein diets or sulfur dysregulation.
  3. Neuropathy can be caused by B6 supplements, and there is a need to rethink the traditional concept of B6 'toxicity' and consider individual differences in tolerance levels.
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Making Sense of Supplements

The Vajenda • 3773 implied HN points • 28 Jan 24
🏥 Health & Wellness Supplements
  1. Supplements include vitamins, minerals, herbal products, and more.
  2. Fiber supplements can help with constipation when food intake falls short.
  3. Be cautious with multi-ingredient supplements making broad health claims, as they are often untested and lack evidence.

ex150nosauce+ACV-3 review: it works.. when you do it

Experimental Fat Loss • 134 implied HN points • 12 Feb 26
🏥 Health & Wellness Supplements
  1. The nosauce plus ACV approach yields reliable weight loss after an initial rapid water drop and is inexpensive and sustainable when followed.
  2. The diet is fragile: even modest cheats like extra beef, extra vegetables, sour cream, high-sodium drinks, or bread commonly produced stalls and increased hunger.
  3. Refeed behavior shows starches (sourdough, rice and beans) satisfy cravings reasonably well, while large high‑protein meals tended to trigger insatiable hunger and overeating.

My Iron Deficiency Protocol

Harnessing the Power of Nutrients • 1078 implied HN points • 04 Jun 24
🏥 Health & Wellness Supplements
  1. Iron deficiency can manifest in various symptoms beyond anemia, including low sex hormones, fatigue, and hair loss.
  2. Optimizing iron levels can have significant impacts on hormone balance, immunity, and overall well-being, especially during aging.
  3. The iron deficiency protocol includes guidance on foods, supplements, inflammation management, and genetic factors to consider.

Case Report: Sigmoid Colon Adenocarcinoma Stage II, age 70, Female

2nd Smartest Guy in the World • 2535 implied HN points • 10 Feb 24
🏥 Health & Wellness Supplements
  1. Using fenbendazole along with other supplements was successful in treating colon cancer in this Case Report.
  2. Alternative treatments like ivermectin and fenbendazole were effective even after declining traditional chemotherapy.
  3. The combination therapy of ivermectin and fenbendazole showed promising results in cancer treatment, with supporting evidence from a top researcher.

The Mitochondrial Nutrient Missing From Every Supplement

Harnessing the Power of Nutrients • 2536 implied HN points • 30 Jan 24
🏥 Health & Wellness Supplements
  1. There's a key nutrient, MK-4, crucial for mitochondrial health that is often missing from many supplements.
  2. MK-4 and CoQ10 have similar structures and roles in the respiratory chain, but play distinct functions and cannot substitute each other.
  3. For optimal mitochondrial support, it's recommended to include MK-4 alongside CoQ10 in a ratio of around 1 microgram of MK-4 for every 1 milligram of CoQ10.

Is Vitamin C Destroying Your Mitochondria?

Harnessing the Power of Nutrients • 1617 implied HN points • 17 Feb 24
🏥 Health & Wellness Supplements
  1. High doses of Vitamin C can inhibit CoQ10 synthesis and decrease copper status, affecting mitochondrial function.
  2. Excessive Vitamin C intake can lead to the generation of oxalate, a mitochondrial toxin, causing potential mitochondrial damage.
  3. While high doses of Vitamin C can have benefits in specific cases, for general use, it's safer to stick to doses from a Vitamin C-rich diet.

A Simple DIY Home Test for Molybdenum Deficiency

Harnessing the Power of Nutrients • 1437 implied HN points • 25 Feb 24
🏥 Health & Wellness Supplements
  1. Molybdenum is crucial for converting toxic sulfite to useful sulfate in the body. Deficiency can lead to various health issues like anxiety, sleep problems, and more.
  2. Lab testing for molybdenum status is often inadequate, with tests focused on ruling out toxicity rather than assessing deficiency.
  3. A simple DIY home test for molybdenum status can be done with minimal equipment, a molybdenum supplement, and a few days of data collection, providing a potentially more practical approach to monitoring levels.

Cheat Sheet Version 3!

Harnessing the Power of Nutrients • 499 implied HN points • 03 Jun 24
🏥 Health & Wellness Supplements
  1. Cheat Sheet Version 3 provides new information on iron and manganese, includes free copper calculations, and aligns with the Comprehensive Nutritional Screening for simplicity.
  2. Masterpass members have exclusive access to Version 3 of Testing Nutritional Status: The Ultimate Cheat Sheet and all future updates.
  3. The Cheat Sheet has been updated to be more user-friendly and compatible with the Comprehensive Nutritional Screening on the website.

Lithium Orotate for Dementia & Depression

Neuro Athletics • 22 implied HN points • 23 Feb 26
🏥 Health & Wellness Supplements
  1. Brain aging isn’t just about passive “gunk” building up; it’s framed as a metabolic crisis where that buildup is robbing neurons of things they need.
  2. A Harvard study reportedly found that lithium is being hijacked inside the brain, leaving neurons starved of this essential mineral.
  3. A specific over-the-counter form, lithium orotate, can supposedly bypass the trap and reach brain cells, and human clinical trials are cited suggesting lithium can slow or sometimes halt cognitive decline.

NMN Probably Won't Make You Live Forever

Harnessing the Power of Nutrients • 1298 implied HN points • 24 Feb 24
🏥 Health & Wellness Supplements
  1. The new research challenges the belief that supplements like NMN can significantly extend lifespan. High levels of 4PY, a niacin metabolite, were linked to increased cardiovascular inflammation and risk of early death.
  2. Limit niacin supplements to 250 milligrams per day for safety, and focus on meeting nutrient needs through a balanced diet to support NAD+ production.
  3. The study provides important insights on the potential risks of high-dose niacin supplements, highlighting the importance of moderation in supplementation and the need for more research in this area.

What's In Your Prenatal Vitamin?

The Vajenda • 1179 implied HN points • 03 Feb 24
🏥 Health & Wellness Supplements
  1. Be cautious about prenatal vitamins, as they may not always contain the stated nutrients.
  2. Some prenatal vitamins have inadequate folic acid, posing a risk for neural tube defects.
  3. Heavy metals and contaminants in prenatal vitamins need more oversight to ensure safety.

A PhD's Secret Weapon: The Four Biomarkers Every Expert Should, But Doesn’t, Analyze

Harnessing the Power of Nutrients • 1977 implied HN points • 28 Apr 23
🏥 Health & Wellness Supplements
  1. Tests ordered in health space often don't go deep enough to uncover root causes.
  2. When analyzing health biomarkers, considering the main fuels of mitochondria is crucial.
  3. Understanding the ratios and interactions of biomarkers like lactate, pyruvate, and ketones can reveal important insights for mitochondrial function.

The Ultimate Vitamin K2 Resource

Harnessing the Power of Nutrients • 359 implied HN points • 28 Apr 24
🏥 Health & Wellness Supplements
  1. Vitamin K2 has several health benefits, such as improving bone strength, stabilizing blood sugar, enhancing exercise performance, and protecting against cancer.
  2. The different forms of vitamin K2 have unique functions in the body, with MK-7 being effective for bone health and MK-4 playing a role in cancer protection and sexual health.
  3. Getting enough vitamin K2 from food sources like natto, goose liver, cheese, egg yolks, and chicken, or through supplements, is essential for overall health, and it's important to pay attention to form, dosage, and food pairing.

Vitamin C, Whole Food Vs. Synthetic: Does It Matter?

Harnessing the Power of Nutrients • 1018 implied HN points • 07 Nov 23
🏥 Health & Wellness Supplements
  1. Whole food vitamin C is preferred because it provides important nutrients, but it is not fundamentally different from ascorbic acid.
  2. Plant sources of choline and flavonoids do not have high levels of vitamin C, and the absorption of flavonoids in plants is low.
  3. Synthetic ascorbic acid is not structurally different from natural vitamin C; however, natural sources like whole food supplements offer additional nutrients and benefits.

Hormones Are Never In Charge

Harnessing the Power of Nutrients • 1018 implied HN points • 26 Oct 23
🏥 Health & Wellness Supplements
  1. Hormones are not the primary cause of problems and are simply messengers between tissues.
  2. Hormones can be affected by factors like nutrient deficiencies, body fat levels, and energy metabolism issues.
  3. Addressing the root causes of hormonal imbalances through optimizing body composition, correcting nutrient deficiencies, and managing energy metabolism can be more effective than relying solely on hormone treatments.

The Dark Side of Biotin

Harnessing the Power of Nutrients • 998 implied HN points • 23 Oct 23
🏥 Health & Wellness Supplements
  1. Biotin and other supplements can have harmful effects on the body's energy metabolism if not balanced properly.
  2. Measuring waking fasting lactate levels can be a useful way to monitor and identify potential metabolic issues caused by supplementation.
  3. Supplements like thiamin, B6, and biotin can cause increases in lactate levels, indicating a metabolic imbalance that may lead to health problems.

Well Being: Broccoli, A True Superfood

Who is Robert Malone • 22 implied HN points • 04 Feb 26
🏥 Health & Wellness Supplements
  1. Broccoli — especially young broccoli sprouts — is a top source of glucoraphanin that converts into sulforaphane, a signaling compound that turns on the body’s detox, antioxidant, and cell‑regulation systems and may lower cancer risk over time.
  2. That conversion needs the enzyme myrosinase, which cooking often destroys, so eating raw sprouts, pairing cooked broccoli with mustard (or using supplements that include myrosinase) improves how much sulforaphane your body actually gets.
  3. Growing organic broccoli sprouts at home is easy and gives you a very concentrated, low‑residue source of these protective compounds that are best eaten raw or added after cooking to preserve their benefits.

Why High-Dose Biotin Could be the Answer for Your Blood Sugar, Neurological Health, and Skin Health

Harnessing the Power of Nutrients • 1557 implied HN points • 19 Jan 23
🏥 Health & Wellness Supplements
  1. High-dose biotin can help with issues like diabetes and smell/taste disorders, but may not be suitable for everyone - consulting a healthcare professional is important.
  2. Some studies suggest high-dose biotin can worsen conditions like multiple sclerosis and even cause adverse effects on blood sugar levels.
  3. Finding the right biotin dosage is crucial, as too much can lead to errors in lab tests and potential serious health consequences, while most people may need more biotin than they currently get.

Questions on NAC, biofilms, vitamin C and brain fog, energy metabolism driving autoimmune disorders.

Harnessing the Power of Nutrients • 918 implied HN points • 30 May 23
🏥 Health & Wellness Supplements
  1. N-acetylcysteine (NAC) can disrupt biofilms at specific doses but may harm gut health with chronic use.
  2. Vitamin C can lead to muscle pain, joint pain, and brain fog due to oxalate crystals and energy metabolism issues.
  3. Autoimmune conditions might be linked to deficiencies in vitamins A and D impacting energy metabolism, potentially causing vitamin A activation issues.

Erythritol and Blood Clotting

Harnessing the Power of Nutrients • 1258 implied HN points • 14 Mar 23
🏥 Health & Wellness Supplements
  1. Erythritol may contribute to cardiovascular disease by increasing blood clotting propensity, especially in individuals with high erythritol levels.
  2. Understanding the polyol pathway and pentose phosphate pathway is crucial for comprehending how erythritol metabolism affects thiamin deficiency and oxidative stress.
  3. Plasma erythritol likely serves as a marker of pentose phosphate pathway activation, indicating NADPH depletion and suboptimal thiamin status.

Biotin’s Health Benefits: Way Beyond Hair and Nails

Harnessing the Power of Nutrients • 718 implied HN points • 25 Oct 23
🏥 Health & Wellness Supplements
  1. Biotin deficiency can cause a range of symptoms like moodiness, hair loss, and muscle pain, but these are reversible with biotin supplementation.
  2. Biotin is crucial for various bodily functions beyond hair and nails, such as regulating cholesterol levels and improving taste loss in certain cases.
  3. The recommended biotin intake varies based on protein consumption, with the general rule being to consume at least 150 micrograms per day from a diet rich in animal products and fresh produce.

Can Biotin Help Detoxify Oxalate?

Harnessing the Power of Nutrients • 1318 implied HN points • 06 Feb 23
🏥 Health & Wellness Supplements
  1. The hypothesis presented suggests that biotin-dependent enzyme pyruvate carboxylase may detoxify oxalate by converting it to formate, which could then be utilized in methylation or further metabolism.
  2. Biotin deficiency might lead to oxalate intolerance, implying the importance of biotin in promoting oxalate clearance.
  3. The interesting discussion around biotin and oxalate interactions opens up possibilities for further research into how biotin may play a role in detoxifying oxalate, potentially impacting how we approach certain health conditions.

Why Would Citrate or Malate Cause Insomnia?

Harnessing the Power of Nutrients • 659 implied HN points • 18 Aug 23
🏥 Health & Wellness Supplements
  1. Citrate and malate in supplements can cause insomnia for different people, suggesting individual differences in energy metabolism.
  2. The opposite reactions to citrate and malate indicate underlying idiosyncrasies in energy metabolism.
  3. Consider exploring metabolic issues or mold contamination as possible reasons for experiencing insomnia from citrate or malate supplements.

The Fasting-Feeding Reset

Harnessing the Power of Nutrients • 1158 implied HN points • 31 Jan 23
🏥 Health & Wellness Supplements
  1. The concept of a Fasting-Feeding Reset involves stacking supplements to optimize both fasting and feeding states for tissue health.
  2. Fasting is not suitable for everyone, especially pregnant/lactating women, children, or those with certain medical conditions.
  3. The fasting-feeding reset approach aims to clean up damaged tissue during fasting and rebuild healthy tissue during feeding for immune system improvements.

Can Dietary Supplements Do Harm?

Are You Okay? • 619 implied HN points • 07 Aug 23
🏥 Health & Wellness Supplements
  1. Nature is beneficial, but not all solutions come in pill form. Many health issues can be addressed by examining and adjusting everyday habits.
  2. Be cautious with dietary supplements and always consider potential interactions with medication. Speak to your doctor about all the supplements you are taking.
  3. Check the credibility of information sources when considering supplements. Not all supplements are regulated closely, so it's important to seek certified products and reliable sources.