The hottest Toxicity Substack posts right now

And their main takeaways
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Top Science Topics

This Is What Causes B6 "Toxicity"

Harnessing the Power of Nutrients • 1977 implied HN points • 21 May 24
🏥 Health & Wellness Nutrition Toxicity Supplements
  1. Vitamin B6 is essential for various bodily functions like preventing low blood glucose, maintaining muscle health, and improving skin condition.
  2. Estrogen and inflammation can increase the body's need for B6, so monitoring intake is crucial, especially for individuals with high-protein diets or sulfur dysregulation.
  3. Neuropathy can be caused by B6 supplements, and there is a need to rethink the traditional concept of B6 'toxicity' and consider individual differences in tolerance levels.

Thiamin Supplements: Not For Everyone

Harnessing the Power of Nutrients • 1697 implied HN points • 19 Feb 24
🏥 Health & Wellness Nutrition Supplementation Metabolism Mitochondria Toxicity
  1. Thiamin is crucial for various functions like stable blood glucose, calmness, tissue health, detoxification, and athletic performance.
  2. Thiamin deficiency can lead to issues such as mitochondrial dysfunction, nerve problems, and eyesight deterioration.
  3. Excessive thiamin supplementation may cause adverse effects and stress on metabolic pathways, so it's important to be mindful of when to supplement thiamin and when to stop.

PART 1: Should rosuvastatin (Crestor®) be withdrawn from the market?

Maryanne Demasi, reports • 1906 implied HN points • 29 Jan 24
🏥 Health & Wellness Medication Marketing Toxicity Cholesterol
  1. Rosuvastatin (Crestor®) quickly became a popular cholesterol-lowering drug due to an aggressive marketing campaign.
  2. In Australia, rosuvastatin is the most prescribed drug, with over 14 million prescriptions written in a financial year.
  3. Rosuvastatin was found to be the most potent statin in lowering cholesterol, but this higher potency also led to greater toxicity.

CoQ10 Deficiency Is Sulfur Toxicity

Harnessing the Power of Nutrients • 1358 implied HN points • 12 Mar 24
🏥 Health & Wellness Nutrition Toxicity Supplementation Metabolism Genetics
  1. CoQ10 deficiency is linked to sulfur toxicity, impacting various bodily functions and potentially causing issues like anxiety after eating meat or taurine consumption.
  2. Hydrogen sulfide, a necessary gasotransmitter, can turn toxic at high concentrations, affecting the body's ability to convert food energy to ATP.
  3. Taurine can help counteract the effects of sulfur toxicity by suppressing the trans-sulfuration pathway, which can prevent the overproduction of hydrogen sulfide and sulfite.

Manganese Toxicity Is a CoQ10 Deficiency

Harnessing the Power of Nutrients • 998 implied HN points • 11 Mar 24
🏥 Health & Wellness Nutrition Supplementation Toxicity Oxidative stress
  1. Excess manganese can lead to mitochondrial dysfunction by hindering CoQ10 synthesis.
  2. Manganese toxicity disrupts ATP production, causes oxidative stress, and hampers CoQ10 levels, impacting energy generation.
  3. CoQ10 supplementation, along with managing manganese levels and ensuring adequate iron, may help address issues related to CoQ10 synthesis and toxicity.
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Science and Serendipity

Dr’s Newsletter • 746 implied HN points • 11 Feb 24
🔬 Science Research Chemistry Toxicity
  1. PhD research can be challenging but can lead to unexpected and serendipitous discoveries
  2. The stability of certain compounds is crucial in preventing toxicity, as observed in experiments with aluminium and silicic acid in fish
  3. Understanding the chemistry behind experimental outcomes is key, as seen in the success of a PhD research project despite initial doubts

The Next, Episode #51

The Next Brand • 609 implied HN points • 02 Feb 24
🏥 Health & Wellness Obesity Medical Industry Nutrition Chronic Disease Toxicity
  1. Ozempic, a GLP-1 agonist, is being hyped as a solution to obesity, but it may not address the real issues of metabolic health in America.
  2. Ozempic, despite its weight loss claims, may result in serious side effects, including muscle and bone loss, gastrointestinal events, and more.
  3. The push to fund drugs like Ozempic with taxpayer money raises concerns about cost, corruption, and missed opportunities to address root causes of health issues.

Protecting Against Spike Protein Toxicity With Sulfur, Selenium, and Sunlight

Harnessing the Power of Nutrients • 1318 implied HN points • 11 Apr 22
🏥 Health & Wellness Nutrition Toxicity
  1. The spike protein may cause harm at low concentrations, but the body has natural defenses like heat shock proteins to counteract this.
  2. HSP90 inhibitors could potentially protect against spike protein toxicity, but they may come with serious side effects.
  3. Instead of pharmaceuticals, exploring natural ways like incorporating sulfur, selenium, and sunlight into our diet and lifestyle may offer benefits without harmful side effects.

Boracherro: The Flower That Charms & Harms

Tripsitter • 79 implied HN points • 24 Aug 23
🏥 Health & Wellness Psychedelics Plants Toxicity Folklore
  1. The Boracherro tree, also known as Angel's Trumpets, may seem beautiful but contains psychoactive compounds that can be deadly and induce intense hallucinations.
  2. Brugmansia, a genus of ornamental shrubs including Boracherro, have vibrant flowers and are extinct in the wild but abundant in cultivation, with psychoactive properties.
  3. Boracherro contains tropane alkaloids like scopolamine that can lead to delirium, vivid hallucinations, and dangerous side effects, emphasizing the importance of caution and shamanic guidance in its use.

Vitamin A

Harnessing the Power of Nutrients • 219 implied HN points • 27 Jun 22
🏥 Health & Wellness Nutrition Supplementation Toxicity Symptoms Prevention
  1. Vitamin A is crucial for multiple bodily functions including maintaining moist eyes, smooth skin, strong immunity, healthy vision, and sleep.
  2. Vitamin A is important for vision as it helps the eyes sense light and transmit signals to the brain, impacting both night and day vision.
  3. Getting enough vitamin A from foods involves understanding the difference between plant and animal forms, the need for fats to aid absorption, potential deficiencies and toxicity risks, and how to adjust intake based on dietary preferences or requirements.

Graphene: New Comprehensive Study, Degradation, and Industry Trends

Tessa Fights Robots • 43 implied HN points • 06 Mar 24
🔬 Science Research Toxicity Applications Biology Industry
  1. A recent study highlighted the toxicity and degradation of graphene, raising concerns about its broad applications and potential hazards on the environment and human health.
  2. Further research is needed on the degradation of graphene-based nanomaterials to understand their environmental impact and health risks. Some compounds like humic acid and specific enzymes play a role in the biodegradation process.
  3. Graphene is a trending material in various industries, but there are growing concerns about its safety, likening it to the new asbestos or Glyphosate 2.0. Monitoring industry trends and applications of graphene is important for understanding its impact.

PFAS in non-stick pans: how fast does it migrate to food?

Molecular Spectacular • 21 HN points • 03 Apr 24
🏥 Health Politics Toxicity Health Risks Chemicals Food Safety Regulations
  1. PFAS can move from non-stick pans to food while cooking. Research shows that this transfer can vary widely, depending on how often the pan is used.
  2. Cooking multiple meals with a non-stick pan can lead to higher levels of PFAS in your food. Studies suggest that even cooking just 4 meals a day might put people over the safe limit for PFAS exposure.
  3. Using salt in food can increase the amount of PFAS that transfers from the pan to the meal. Additionally, reusing the same pan seems to boost PFAS levels in each successive meal.

Actually, the internet's always been this bad

Links I Would Gchat You If We Were Friends • 3 HN points • 21 Mar 24
🕹 Technology Internet Social Platforms Online Discourse Toxicity Moderation
  1. Online discourse has remained consistently toxic over the past 30 years, challenging the belief that it has worsened.
  2. Toxicity in conversations tends to increase the longer they go on, involving fewer but more active participants.
  3. Platforms exhibit similar levels of toxic comments, and moderation policies have the potential to influence the spread of toxic content.

028: Why You Should Manage Your Zinc Status and How to Do It

Harnessing the Power of Nutrients • 19 implied HN points • 04 Mar 17
🏥 Health & Wellness Nutrition Supplementation Deficiency Toxicity
  1. Zinc is crucial for skin health, immune function, and glucose tolerance, and is essential for antioxidant defense.
  2. Signs of zinc deficiency include dry skin, poor wound healing, increased infections, and poor glucose tolerance. Zinc-rich foods are best from animal sources like oysters, red meat, and cheese.
  3. Excess zinc can lead to copper deficiency, impacting immune function. It's important to take zinc supplements in balanced doses with copper, on an empty stomach, and in divided doses if needed.

026: Why You Should Manage Your Copper Status and How to Do It

Harnessing the Power of Nutrients • 19 implied HN points • 03 Feb 17
🏥 Health & Wellness Nutrition Supplementation Research Deficiency Toxicity
  1. Copper is an essential nutrient with a variety of important roles in the body, and managing your copper status is crucial for overall health.
  2. Copper deficiency can lead to serious health issues like anemia, osteoporosis, and mental imbalances, so it's important to ensure you are getting adequate copper through diet or supplementation.
  3. Good food sources of copper include liver, oysters, mushrooms, seaweed, and whole grains, while supplementing with copper should only be done in cases of verified deficiency and caution should be taken with the amount.

Vitamin D is Synthesized From Cholesterol and Found in Cholesterol-Rich Foods

Harnessing the Power of Nutrients • 19 implied HN points • 20 Dec 08
🏥 Health & Wellness Vitamin D Cholesterol Nutrition Toxicity
  1. Vitamin D is synthesized from cholesterol in the body, and it can also be obtained from cholesterol-rich foods.
  2. Sunlight exposure is crucial for the synthesis of vitamin D in the skin, but factors like latitude, time of year, and atmospheric conditions can affect this process.
  3. Cholesterol-rich foods, like cod liver oil and fatty fish, are among the richest dietary sources of vitamin D, highlighting the importance of consuming both vitamin D and cholesterol for optimal health.

Remdesivir Is Probably a Reproductive Toxin, and Its Benefit Is Unclear

Harnessing the Power of Nutrients • 0 implied HN points • 04 May 20
🏥 Health Politics Research Mortality Toxicity Treatment Fertility
  1. The benefit of remdesivir in COVID-19 patients is uncertain, with conflicting results from different studies.
  2. Remdesivir could have a time-dependent effect, showing potential benefits when given early in the course of the disease and potential harm when given late.
  3. There are concerns about the reproductive toxicity of remdesivir, particularly in male mice, raising questions about its impact on fertility in humans.

The Cholesterol Times, Issue #010 -- Redefining Heart Disease: Discovering Vitamin K All Over Again

Harnessing the Power of Nutrients • 0 implied HN points • 17 Oct 23
🏥 Health & Wellness Nutrition Disease Research Toxicity Antioxidants
  1. Dietary cholesterol may be essential for some individuals with genetic defects in cholesterol synthesis.
  2. Vitamin K plays a crucial role in preventing arterial calcification and atherosclerosis.
  3. High-heat cooking can turn meat into a source of toxic compounds like acrylamide, emphasizing the need to consider cooking methods for health.