The hottest Medication Substack posts right now

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Top Health & Wellness Topics

The onward march of semaglutide and friends

Brain Pizza • 662 implied HN points • 22 Oct 24
🏥 Health Politics Medication Addiction Diabetes Research Public Health
  1. New diabetes drugs, like GLP-1 agonists, may help reduce cravings for alcohol and opioids. This suggests they could be useful for treating substance use disorders.
  2. These medications were originally designed for weight loss and diabetes management, but they are showing potential in other areas of health.
  3. The findings from recent studies hint at a broader impact of these drugs, which could change how we approach treatment for various health conditions, not just diabetes.

Semaglutide Kind of Life

Freddie deBoer • 5662 implied HN points • 15 Mar 24
🏥 Health & Wellness Medication Weight management Exercise Mental health
  1. The author started taking a medication called Rybelsus due to metabolic problems caused by long-term use of psychiatric medications and physical limitations.
  2. The author's struggles with weight management, loss of control due to inability to lift weights, and the significant cost of medication highlight the challenges they face in trying to maintain their health.
  3. Regular monitoring and support from professionals are essential for the author's well-being, despite concerns about societal judgment around medication use.

Dr. Paul Marik On Ivermectin and Cancer: “We know of cases of patients who had solid tumors...and together with some other drugs... the cancer disappeared."

2nd Smartest Guy in the World • 3832 implied HN points • 21 Jan 24
🏥 Health & Wellness Treatment Medication Cancer Disease Safety
  1. Ivermectin, known as 'horse dewormer,' is now proving to be a powerful cancer treatment protocol.
  2. Combining Ivermectin with Fenbendazole creates a potent anti-cancer, anti-parasitic, and anti-viral therapy.
  3. Doctors suggest cancer may be related to intracellular parasites and Ivermectin may help in treating it.

A Surprising Fix for Weight Gain, Digestive Woes & Skeletal Pain

Are You Okay? • 3095 implied HN points • 19 Feb 24
🏥 Health & Wellness Mental health Physical health Therapy Medication Self-compassion
  1. Self-compassion is a crucial element for overall health, often more important than medication for certain symptoms.
  2. Non-pharmacologic interventions are commonly prescribed alongside medications to address complex health problems like weight gain, insomnia, and chronic pain.
  3. Self-compassion, forgiveness, and love for oneself can be the most effective remedies for inner struggles and health issues, often more powerful than medication.
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If at first you don't succeed

Disaffected Newsletter • 1858 implied HN points • 24 Mar 24
🏥 Health & Wellness Mental health Personal Growth Self-care Medication Depression
  1. It's okay to seek help when struggling with mental health. Sometimes, taking medication like an SSRI can really make a difference.
  2. Experiencing tough times like despair and insomnia is really hard, but it's important to keep trying to find solutions.
  3. Getting back to feeling better might take time, but small improvements can lead to being able to do everyday tasks again.

IMPORTANT REPOST: Synergistic pairing of ivermectin and fenbendazole found HIGHLY EFFECTIVE at preventing and treating cancer

2nd Smartest Guy in the World • 2555 implied HN points • 06 Feb 24
🏥 Health & Wellness Prevention Treatment Cancer Medication
  1. A synergistic pairing of ivermectin and fenbendazole is highly effective at preventing and treating cancer.
  2. Both ivermectin and fenbendazole show promise in inhibiting the growth and spread of cancerous tumors.
  3. Combining ivermectin and fenbendazole with other anti-cancer nutrients like quercetin, vitamins C and D, and curcumin can enhance their effects.

A Surprising Look at the Evidence for Beta-Blockers After MI

Sensible Medicine • 2948 implied HN points • 15 Jan 24
🏥 Health & Wellness Cardiology Medication Trials Heart Health Patient Care
  1. Beta-blockers after MI have been a common practice, but recent evidence shows they may not be as crucial as previously thought.
  2. The BHAT and ISIS 1 trials from the 1980s provided insights on the effectiveness of beta-blockers after MI.
  3. These trials highlight the need to reevaluate the use of beta-blockers after MI, as current MI treatment practices have evolved significantly.

10x happiness increases are possible, and this is an underrated fact

Sasha's 'Newsletter' • 2454 implied HN points • 14 Mar 24
🏥 Health & Wellness Mental health Therapy Physical health Social Connections Medication
  1. Happiness is not a fixed state; significant increases in happiness are achievable through various factors like medication, career growth, physical activities, and personal growth.
  2. Factors contributing to increased happiness include therapy, meditation, improved social connections, financial stability, and positive life changes.
  3. Belief in static happiness levels may limit people from realizing their potential for significant happiness increases, preventing them from actively working towards a happier life.

Mental Health is Health 🧠

Are You Okay? • 1737 implied HN points • 18 Mar 24
🏥 Health & Wellness Mental health Wellbeing Therapy Medication Awareness
  1. Mental health is a crucial aspect of overall health, affecting our thoughts, feelings, and behaviors, as well as our physical health. It is not just about happiness but about acknowledging and working on our fears, moods, habits, and relationships.
  2. Being aware of our mental health, accepting the things we cannot change, and taking action over the things we can control are important steps in managing mental health.
  3. Addressing mental health issues is a nuanced process that may involve a combination of medication, therapy, lifestyle changes, and self-discovery. It requires a holistic approach considering bio-psycho-social elements.

PART 1: Should rosuvastatin (Crestor®) be withdrawn from the market?

Maryanne Demasi, reports • 1906 implied HN points • 29 Jan 24
🏥 Health & Wellness Medication Marketing Toxicity Cholesterol
  1. Rosuvastatin (Crestor®) quickly became a popular cholesterol-lowering drug due to an aggressive marketing campaign.
  2. In Australia, rosuvastatin is the most prescribed drug, with over 14 million prescriptions written in a financial year.
  3. Rosuvastatin was found to be the most potent statin in lowering cholesterol, but this higher potency also led to greater toxicity.

Sedated granny with deadly toxic drugs like propofol, midazolam, lorazepam, fentanyl, diamorphine etc.), knowing breathing was already suppressed & the toxic drugs suppressed her breathing even more,

Alexander News Network -Dr. Paul Elias Alexander's substack • 1395 implied HN points • 05 Feb 24
🏥 Health & Wellness Healthcare Medication Elderly Care Pandemic response
  1. Sedation of elderly patients with toxic drugs can worsen their breathing and health.
  2. Some medical professionals neglected and mistreated elderly patients during the COVID-19 crisis.
  3. It's important to have an emergency preparedness kit with essential medications.

Reader Question: What is Food Noise?

Weight and Healthcare • 798 implied HN points • 06 Apr 24
🏥 Health & Wellness Nutrition Weight Loss Healthcare Medication Body Image
  1. Be cautious of the concept of 'food noise' promoted by weight loss drug makers as a rebranding of normal hunger or a way to profit off people's broken relationships with food.
  2. Some weight loss drugs aim to manipulate hunger signals through impacting the brain and gut, with unclear long-term effects and potential risks.
  3. The weight loss industry's push for drugs like GLP-1 agonists raises concerns about informed consent, lack of long-term research, and prioritizing short-term weight loss over potential health consequences.

Wegovy for Cardiovascular Risk Reduction - Part 2

Weight and Healthcare • 659 implied HN points • 17 Apr 24
🏥 Health & Wellness Weight Loss Cardiovascular Health Research Medication
  1. The trial data for Semaglutide (Wegovy) for cardiovascular risk reduction was manipulative and lacking in transparency, raising concerns about conflicts of interest and data sharing.
  2. The study demographics were concerning, with a lack of diversity and representation, particularly skewed towards white men, older participants, and those with existing heart disease.
  3. The actual cardiovascular risk reduction with Semaglutide was much lower than claimed, highlighting issues with study design, data presentation, and potential overemphasis on specific demographics in the results.

Side Effects With Progesterone/Progestins in MHT

The Vajenda • 1139 implied HN points • 07 Feb 24
🏥 Health & Wellness Hormone Therapy Mental health Medication Menopause Women's Health
  1. Reproductive hormones can have different effects on women, such as premenstrual syndrome and postpartum depression.
  2. Progesterone/progestins in menopausal hormone therapy can impact mood and may have complex interactions in the brain.
  3. Options to consider if progesterone/progestins negatively affect quality of life include switching dosage or trying alternative medications.

Is it Time to Start An Antidepressant?

Are You Okay? • 1238 implied HN points • 22 Jan 24
🏥 Health & Wellness Mental health Treatment Medication Therapy Symptoms
  1. Depression is a medical condition, not a flaw. Seeing your doctor is crucial.
  2. Treatment options for depression vary and can include therapy, lifestyle changes, or medication like Prozac, Lexapro, and Zoloft.
  3. Pharmacotherapy, like antidepressants, can be beneficial in managing depression when used as part of a holistic treatment plan.

Quick Guide: Wegovy/Ozempic for Weight Loss

Weight and Healthcare • 1118 implied HN points • 10 Jan 24
🏥 Health & Wellness Weight Loss Medication Side Effects Healthcare Industry
  1. Ozempic and Wegovy are different brand names for the same drug used for weight loss.
  2. Wegovy is not just a weight loss drug but a megadose of a diabetes drug with weight loss as a side effect.
  3. Wegovy has serious side effects including complications when going off the drug and the need for continuous use to maintain weight loss.

Zepbound/Mounjaro (Tirzepatide) for Weight Loss - Part 1

Weight and Healthcare • 818 implied HN points • 03 Feb 24
🏥 Health & Wellness Medication Weight Loss Side Effects Dosage Research
  1. Tirzepatide, known as Zepbound for weight loss, was initially a Type 2 diabetes medication by Eli Lilly that got FDA approval for weight loss due to its side effect of weight loss. It works by interfering with normal digestion processes and hunger signals.
  2. There are dosing differences between the diabetes and weight loss applications of Tirzepatide. For weight loss, patients are encouraged to continuously increase the dosage to the highest tolerable level, potentially facing side effects that impact their quality of life.
  3. The side effects of Tirzepatide/Zepbound can range from mild discomfort to serious conditions like thyroid C-Cell tumors, gastrointestinal diseases, and pancreatic issues. Patients need to be aware of potential risks, like drug interactions and impact on pregnancy.

If You Didn't Comply During COVID You're a Psychopath

Break Free with Karen Hunt • 1454 implied HN points • 02 Jul 23
🏥 Health & Wellness Psychology Mental health Medication Influence History
  1. Psychologists can label non-compliance during COVID as psychopathy, justifying 'fixing' individuals as they see fit.
  2. The power dynamics post-COVID have allowed for the manipulation and control of citizens, using psychology as a weapon.
  3. Psychiatry and psychology have a history of coercion, drugging, and inhumane treatments towards those deemed non-compliant or ill.

Q&A: helping a loved one with anxiety; Ozempic hair loss; lung cancer screening; & heart rate variability

Are You Okay? • 439 implied HN points • 22 Mar 24
🏥 Health & Wellness Mental health Medication Anxiety Therapy COVID-19
  1. During the pandemic, many experienced heightened anxiety, including fears around COVID, leading to mental health challenges that may persist post-pandemic. It's crucial to validate experiences, offer empathy, and seek professional help to address anxiety disorders effectively.
  2. Examine potential side effects of medications like GLP1 agonists such as Ozempic, Wegovy, and others, which may cause mild hair loss. Healthcare providers should consider these effects when prescribing and monitor patients accordingly.
  3. The approach to addressing health-related anxiety is multi-faceted, involving psychotherapy, medication, trauma therapy, or even exposure to the feared illness under professional guidance, emphasizing the importance of a comprehensive approach to treatment.

Reader Question - What's With Eli Lilly's Oscar Ad

Weight and Healthcare • 439 implied HN points • 20 Mar 24
🏥 Health & Wellness Medication Weight Loss Healthcare system Insurance Coverage FDA Approval
  1. Eli Lilly and other pharmaceutical companies are focused on lobbying for insurance coverage of weight loss drugs, pushing for the idea of higher-weight bodies as a 'disease' worth medicating.
  2. The FDA approval for weight loss drugs like Zepbound requires different criteria based on BMI, raising concerns about the risk assessments being tied to body size.
  3. Pharmaceutical companies like Eli Lilly prioritize shareholder interests over customer concerns, raising questions about the true motivations behind their actions.

Friday Q&A: osteoporosis; Paxlovid; COVID misinformation; & breathing and heart rate

Are You Okay? • 619 implied HN points • 29 Dec 23
🏥 Health & Wellness Physical health Mental health Exercise Nutrition Medication
  1. Engaging in weight-bearing exercises like yoga can improve bone density and reduce the risk of osteoporosis, along with a calcium-rich diet and vitamin D supplements.
  2. For older adults, incorporating simple weight-bearing exercises into routines, like wearing a weighted vest while walking, can significantly enhance muscle strength and overall health.
  3. Decisions on medications for osteoporosis should be personalized, considering the effectiveness of lifestyle changes and the potential benefits of prescriptions like Fosamax, which may be complemented by habits like yoga.

Friday Q&A: Hormonal mood swings; tapering antidepressants; HRT and breast cancer; & long COVID

Are You Okay? • 499 implied HN points • 26 Jan 24
🏥 Health & Wellness Mental health Physical health Therapies Medication Women's Health
  1. Premenstrual Dysphoric Disorder (PMDD) is a real and potentially debilitating condition that affects many women. Managing it can involve tracking symptoms, regular exercise, a nutritious diet, adequate sleep, hormonal treatments, SSRIs, psychotherapy, and stress reduction techniques.
  2. When considering tapering off antidepressants, it's important to discuss this process with a healthcare provider. Psychotherapy can be a valuable tool for retraining the brain during this transition.
  3. Individualized treatment plans are crucial for addressing specific symptoms and needs when managing hormonal mood swings, tapering antidepressants, or dealing with other health concerns. Working closely with a doctor can help in developing a suitable plan.

Wegovy Side Effects and Informed Consent - Part 2

Weight and Healthcare • 579 implied HN points • 04 Nov 23
🏥 Health & Wellness Medication Informed consent Side Effects Healthcare Weight Loss
  1. Wegovy is a weight-loss drug that has not been around for a long time, as it is a repurposed version of another drug called semaglutide, with evolving risks and warnings.
  2. Wegovy and Ozempic differ in dosage and treatment purpose, with Wegovy aiming to maximize weight loss side effects at a high dose that exceeds the maximum dose of Ozempic.
  3. Informed consent conversations with healthcare practitioners are essential, especially when considering drugs like Wegovy with significant side effects and dosage differences.

Friday Q&A: assessing COVID risk; Ozempic/Mounjaro; booster shots; & CBD gummies for sleep

Are You Okay? • 459 implied HN points • 15 Dec 23
🏥 Health & Wellness COVID-19 Medication Weight Loss Vaccination Mental health
  1. It's important to balance the risks associated with COVID-19 with the desire for social interaction and living a fulfilling life.
  2. Protecting against serious COVID outcomes involves getting vaccinated and optimizing health, while preventing infection means avoiding sick individuals and wearing masks in crowded indoor spaces.
  3. Decisions regarding COVID risk mitigation should be personalized, taking into account individual vulnerabilities and risk tolerance, and it's advised to consult with a healthcare provider for tailored advice.

Mixing antidepressants and psychedelics: 5 Questions for psychopharmacologist Kelan Thomas

The Microdose • 589 implied HN points • 05 Jun 23
🏥 Health & Wellness Medication Psychedelics Therapy Treatment Safety
  1. Psychedelic clinical trials often exclude participants taking SSRIs to isolate the effects of the single drug being studied.
  2. The main risk of mixing SSRIs and psychedelics is serotonin toxicity, but in healthy volunteers, the risk seems low.
  3. Tapering off SSRIs can have risks, including the return of depression or anxiety symptoms and serotonin discontinuation syndrome.

Friday Q&A: caregiver burnout; Ozempic; fall allergies vs. viral symptoms; & emotional eating

Are You Okay? • 539 implied HN points • 20 Oct 23
🏥 Health & Wellness Caregiving Medication Nutrition Mental health Self-care
  1. When caring for aging loved ones, it's crucial to prioritize your own mental and physical health to prevent caregiver burnout.
  2. Shift your perception of control to restore agency and self-determination in your life, especially while taking care of others.
  3. In caregiving, meeting your basic biological needs like sleep, talking to someone, eating healthily, and moving your body is essential for long-term wellbeing.

Friday Q&A: Mounjaro vs. Ozempic; forgetfulness; the snoring bed partner; & COVID testing

Are You Okay? • 439 implied HN points • 24 Nov 23
🏥 Health & Wellness Medication Memory Diabetes Obesity Well-being
  1. Mounjaro and Ozempic are medications for treating type 2 diabetes; Mounjaro also has a version for obesity, Zepbound. Both types of drugs improve insulin sensitivity, reduce blood sugar levels, and promote weight loss.
  2. Forgetfulness about simple things like names of familiar items could be a part of normal aging rather than a sign of dementia. However, if there are persistent concerns, it's best to consult a healthcare provider.
  3. Maintaining a balanced lifestyle with a healthy diet, regular exercise, and realistic expectations is essential for the effective use of medications like Mounjaro, Ozempic, and related drugs.

Friday Q&A: Galleri cancer testing; Ozempic; lipoprotein(a) & heart disease; depression vs. seasonal blues

Are You Okay? • 439 implied HN points • 10 Nov 23
🏥 Health & Wellness Medication Preventive measures
  1. The Galleri cancer test is a non-FDA-approved blood test that claims to detect over 50 types of cancer, but has limitations in accuracy with false negatives and false positives.
  2. When it comes to cancer screening, it is crucial to follow evidence-based recommendations such as mammography for breast cancer, colonoscopy for colon cancer, and other specific tests for high-risk individuals.
  3. For those concerned about cancer risk, focusing on known preventive measures like maintaining a healthy lifestyle, limiting alcohol and processed food intake, and regular exercise is important, alongside consulting with a healthcare provider for personalized screening recommendations.

Are High-Dose Antipsychotics More Deadly Than Fentanyl in Kids?

The Frontier Psychiatrists • 294 implied HN points • 15 Jan 24
🏥 Health & Wellness Mental health Medication Risk Factors Drug Safety
  1. Antipsychotic medications can increase the risk of metabolic syndrome and other adverse outcomes in individuals with depression.
  2. Youth treated with higher-dose antipsychotic medications are at risk of increased mortality, especially among vulnerable children.
  3. Treating young adults with high-dose antipsychotic medications can result in significantly more deaths compared to fentanyl, emphasizing the need for better options for vulnerable youth.

This new class of weight loss drugs are costly - but is there a greater price to ignoring the problem?

Second Opinion • 511 implied HN points • 30 May 23
🏥 Health & Wellness Weight Loss Obesity Medication Chronic Disease
  1. Obesity is a complex chronic disease that needs to be treated seriously.
  2. New weight loss drugs are effective and show promising results, but they are costly and come with side effects.
  3. It's important to consider a variety of evidence-based solutions, including lifestyle interventions, in tackling the obesity epidemic.