The hottest Autoimmunity Substack posts right now

Sequencing B and T cell receptors can help diagnose autoimmune diseases. This kind of testing is much faster and could lead to more accurate diagnoses.
Using machine learning and AI makes analyzing the complex data from these receptors easier. The technology can find patterns and help doctors understand patients' conditions better.
In the future, a full immunome could be a standard test to check how well someone's immune system is working. This could help prevent diseases before they become serious.

The brain has a vital connection with the immune system, challenging the old belief that the brain is cut off from it. New studies show that brain immune cells can help prevent and treat diseases.
Recent research has discovered ways to program T cells to respond to brain issues, which may aid in treating brain tumors and autoimmune diseases. This could lead to better therapies by specifically targeting brain conditions.
There is a newly understood communication path between the body and brain that controls inflammation and immune responses. Understanding this connection can improve treatments for autoimmune diseases and conditions like Long Covid.

A new study shows that people who got mRNA Covid vaccines had a 30% higher chance of developing thyroid disease after a year compared to those who didn't get vaccinated. This means many might be facing thyroid issues globally.
The risk of thyroid problems grows over time, and those who received fewer shots in a year had an even higher risk of developing these issues. This suggests that the vaccines might cause long-term autoimmune reactions.
The thyroid plays a crucial role in our metabolism and health, and these newly found connections could lead to serious issues for many people, like heart problems or anxiety, over time.

Celiac disease and gluten intolerance are not just black and white. Some people may show symptoms without having full-blown celiac disease, indicating a spectrum of gluten sensitivity.
There’s still a lot we don’t know about why some people can’t digest gluten. Research suggests that the gut microbiome and certain bacteria might play a role in triggering an immune response.
Possible treatments for celiac disease could involve using targeted therapies, like bacteriophages, to eliminate harmful bacteria and restore a healthy balance in the gut.

Dr. Philip McMillan is discussing long-term health effects of COVID-19, saying many people still feel sick even after recovering. It's important to understand these ongoing issues.
He emphasizes the need for more research into post-COVID conditions and suggests early detection and treatment can help. This could improve public health responses.
McMillan also calls for global cooperation to better manage the lasting impacts of COVID-19. This teamwork is vital to address health challenges that remain.

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Markers like CRP, neutrophil count, and fibrinogen can indicate post-COVID inflammatory symptoms, so these are important to monitor.
Severe COVID cases showed an increase in autoimmunity markers like ANA and anti-carbamylated protein, so it might be wise to include these in precautionary bloodwork.
Certain markers like D-dimer, NT-proBNP, IL-6, among others, were commonly elevated - considering these alongside markers like ferritin and IL-6 can be crucial for post-COVID recovery.