The hottest Microbiome Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

How Our Gut Microbiome Can Drive Sugar Cravings

Ground Truths • 15222 implied HN points • 26 Jan 25
🏥 Health & Wellness Microbiome Nutrition Psychology Diabetes Physiology
  1. Our gut bacteria can influence our cravings for sugar. Specific bacteria in our gut send signals to our brain that can make us want more sweets.
  2. The molecule Ffar4 in our gut plays a big role in how much we like sugar. When this is less active, we might crave sugar more.
  3. A certain type of gut bacteria, called Bacteroides vulgatus, is linked to an increased desire for sugar. Understanding this can help us figure out how to control cravings better.

The Updated Red Meat Story

Ground Truths • 13516 implied HN points • 19 Jan 25
🏥 Health & Wellness Nutrition Diet Microbiome Cognition Epidemiology
  1. Eating a lot of red meat can be linked to health issues like heart problems and cancer. Plant-based diets are usually better for overall health.
  2. Studies show that eating more plant-based foods can help balance the risks from red meat. Even small changes can make a difference in gut health.
  3. Replacing red meat with healthier options like nuts or legumes may reduce the risk of cognitive decline and dementia.

Unraveling the Mysteries of mRNA Vaccine Shedding

The Forgotten Side of Medicine • 6800 implied HN points • 21 Jan 24
🏥 Health & Wellness Vaccines Microbiome Allergies Immune Response Infection
  1. Over the past years, data suggests that unvaccinated individuals may become ill when in close contact with vaccinated individuals; mechanisms for this transmission involve exosome shedding, COVID-19 shedding, and potentially transfected bacterial shedding.
  2. Efforts to unravel the mysteries of mRNA vaccine shedding have revealed concerns such as shedding's impact on sexual shedding, odor emission, blood transfusions, cancer, and mitigation methods.
  3. Various factors can influence shedding reactions, such as sensitivity levels, timing post-vaccination, symptoms experienced, and potential links to the gut microbiome and pheromones.

Gut Bacteria on Steroids

Eat Shit and Prosper • 359 implied HN points • 11 Feb 24
🏥 Health & Wellness Microbiome Hormones Antibiotics Sexual Health
  1. Gut bacteria play a big role in how our bodies handle hormones, like estrogen and testosterone. Antibiotics can upset this balance, which might affect hormone levels and overall health.
  2. The microbiome can recycle hormones that the body has already used, which helps them stick around for longer. When gut bacteria are disrupted, those hormones might just get wasted instead.
  3. Understanding and taking care of our gut bacteria can improve our health and hormonal balance. This might be especially important as we look for natural ways to address health issues.
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Trust Your Gut

Are You Okay? • 459 implied HN points • 17 Apr 23
🏥 Health & Wellness Gut Health Microbiome Stress management
  1. Listen to your gut feelings - they can provide important insights into your overall health.
  2. Maintaining a healthy gut microbiome is essential, as it affects various aspects of our health from digestion to mental well-being.
  3. Managing digestive issues requires a comprehensive approach including awareness of data, acceptance of limitations, and taking proactive steps to improve gut health.

The Time I Accidentally Destroyed My Armpit Microbiome

Eat Shit and Prosper • 219 implied HN points • 10 Dec 23
🏥 Health & Wellness Microbiome Health tips
  1. Using alcohol or other harsh methods can mess up your armpit bacteria, leading to really bad body odor.
  2. It's important to keep a balance in your body’s bacteria, or you might end up needing strong deodorants or treatments to fix the smell.
  3. Some people smell better naturally due to their unique bacteria, and there's potential for finding natural deodorant solutions based on this.

The "Spice" Melange: Exercise, Capsaicin, Cannabinoids, and the Microbiome

Eat Shit and Prosper • 559 implied HN points • 22 Dec 22
🏥 Health & Wellness Nutrition Exercise Microbiome Mental health Lifestyle
  1. Your gut bacteria can affect how much dopamine is released in your brain during exercise, which influences your motivation to work out. So, a healthy gut can boost your exercise performance!
  2. Eating specific foods like fish, olive oil, and mushrooms can help create a good environment for beneficial gut bacteria. This might help improve your drive to exercise.
  3. Simple changes, like adding black pepper to your meals, can activate receptors that support your exercise motivation. Even common spices can have positive effects on your desire to stay active!

So you have to take antibiotics. How do you repair your microbiome?

Eat Shit and Prosper • 359 implied HN points • 22 Apr 23
🏥 Health & Wellness Microbiome Nutrition Antibiotics Gut Health Preventive Care
  1. Be careful with antibiotics; only use them when absolutely necessary. They can mess with your gut health and lead to serious issues if used too often.
  2. Probiotics may not help after taking antibiotics like many think. In fact, they could make things worse, sometimes even permanently changing your gut bacteria.
  3. Eating a healthy and varied diet after antibiotics can help restore your gut bacteria. Focus on whole foods, fruits, vegetables, and stay away from processed stuff for better recovery.

Natto: King of Fermented Foods

Eat Shit and Prosper • 419 implied HN points • 08 Jan 23
🍲 Food & Drink Nutrition Fermentation Health Food culture Microbiome
  1. Natto is a unique fermented soybean food packed with health benefits. It's made using a special bacteria, Bacillus subtilis, which isn't found in many other fermented foods.
  2. It contains important nutrients like vitamin K and PQQ, which can help with energy, stress protection, and overall heart health. Eating natto can enhance the nutrition of other foods you eat it with.
  3. Though its slimy texture might be off-putting, natto has been enjoyed in Japan for centuries and can be delicious when prepared well. Finding it at an Asian grocery store is a good start for trying it out.

Celiac Disease, the Microbiome, and the Gluten Intolerance Spectrum

Eat Shit and Prosper • 339 implied HN points • 12 Feb 23
🏥 Health & Wellness Nutrition Microbiome Autoimmunity Disease Research
  1. Celiac disease and gluten intolerance are not just black and white. Some people may show symptoms without having full-blown celiac disease, indicating a spectrum of gluten sensitivity.
  2. There’s still a lot we don’t know about why some people can’t digest gluten. Research suggests that the gut microbiome and certain bacteria might play a role in triggering an immune response.
  3. Possible treatments for celiac disease could involve using targeted therapies, like bacteriophages, to eliminate harmful bacteria and restore a healthy balance in the gut.

High cholesterol? There's a bug for that.

Eat Shit and Prosper • 259 implied HN points • 21 Feb 23
🏥 Health & Wellness Nutrition Microbiome Heart Health Gut Health
  1. Your liver is the main source of cholesterol in your body, not your diet, so cutting cholesterol from food may not have a big impact. Instead, the body makes its cholesterol for important functions like hormone production.
  2. Certain gut bacteria can convert cholesterol into coprostanol, which is not reabsorbed and helps lower cholesterol levels. Your microbiome's composition determines how effective this process is for you.
  3. Eating foods that promote healthy gut bacteria, like eggs and shellfish, might help manage cholesterol levels better than avoiding them entirely. So, sometimes eating more cholesterol can actually be beneficial.

Probiotics for Kidney Stones?

Eat Shit and Prosper • 239 implied HN points • 21 Jan 23
🏥 Health & Wellness Microbiome Diet Nutrition Probiotics
  1. Kidney stones are quite painful and common, affecting about 1 in 10 people. Calcium oxalate stones form when oxalic acid from food combines with calcium in the body.
  2. The gut bacteria _Oxalobacter formigenes_ was once thought to help prevent kidney stones by breaking down oxalate, but research shows stone-formers have similar amounts of this bacteria as non-stone-formers.
  3. The body's microbiome and dietary factors are more complex than just oxalate levels. Other bacteria and nutrients, like vitamin K, may play a role in calcium handling and kidney stone prevention.

Codon: Notes on Progress #2

Asimov Press • 135 implied HN points • 12 Mar 23
🔬 Science Genetic Engineering Biology Climate change Health Impact Microbiome
  1. A newsletter provides curated insights on scientific progress in biology and future technologies.
  2. Recent advancements include nano-scale probes for space exploration, gene-editing for heart protection, and new gene therapy trials.
  3. Challenges in genetics, predictions of protein levels from DNA sequences, and advancements in microbiome research showcase ongoing developments in the field.

Future of Gut Health and Longevity( Part 10/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 19 implied HN points • 01 Feb 24
🏥 Health & Wellness Gut Health Longevity Microbiome Research Disease Prevention
  1. Advancements in microbiome research have uncovered the importance of gut health in overall well-being and disease prevention.
  2. Personalized medicine based on individual microbiome profiles is a promising frontier that could revolutionize healthcare treatments.
  3. Microbiome-based therapies show potential in redefining treatment approaches for various diseases, particularly those common in aging populations.

Please stop "vaginal seeding"

Eat Shit and Prosper • 79 implied HN points • 18 Oct 22
🏥 Health & Wellness Microbiome Breastfeeding Gut Health
  1. Vaginal seeding, or swabbing a C-section baby with vaginal bacteria, is not helpful for gut health. Most important gut bacteria actually come from breastmilk, not the birth canal.
  2. C-sections can negatively affect a child's microbiome due to factors like antibiotics and the nature of the surgery. This can lead to gut issues later in life.
  3. Breastfeeding is essential for passing on beneficial gut bacteria, and avoiding unnecessary C-sections and antibiotics can improve a child's microbiome.

Eat street food

Natural Selections • 7 implied HN points • 20 Feb 24
🍲 Food & Drink Street Food Culture Microbiome Travel
  1. Travel offers mind-expanding experiences, even if uncomfortable at times, leading to memorable moments and reflection.
  2. Eating street food while traveling can provide a glimpse into local culture, fostering connections, and offering unique culinary experiences.
  3. Sampling street food can impact your gut microbiome positively, contributing to better health and enhancing your overall travel experience.

The Laxative Handbook: Unveiling the Complexities of Gut Health(Part 1/5)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 1 HN point • 29 May 23
🏥 Health & Wellness Gut Health Microbiome
  1. Laxatives play a major role in maintaining digestive health, with a significant market value globally.
  2. Understanding the different types and mechanisms of laxatives is crucial for their proper use and avoiding potential side effects.
  3. The use of laxatives can impact the delicate gut microbiome and may have both positive and negative effects over time.

Case Studies and Research Insights on Microbiome and Disease Prevention( Part 6.5/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 24 Jan 24
🏥 Health & Wellness Microbiome Disease Prevention Research Nutrition Public Health
  1. The gut microbiome is linked to the prevention of specific age-related diseases like cardiovascular conditions and certain cancers.
  2. Specific gut bacterial strains can help metabolize cholesterol, lower its levels, and reduce the risk of heart disease.
  3. Research shows that a balanced microbiome rich in anti-inflammatory strains can help mitigate inflammation pathways and reduce the risk of cancer.

The New Genetics — Part V: Is the Intestinal Microbiome Part of Our Genome?

Harnessing the Power of Nutrients • 0 implied HN points • 18 Apr 11
🔬 Science Genetics Microbiome Inheritance Metabolism Health
  1. Intestinal microbes contribute to our phenotype and are inherited from one generation to the next, challenging assumptions about genetic inheritance.
  2. The co-evolution of humans and their gut flora is vital to consider when discussing human evolution.
  3. Fixing metabolic issues may involve normalizing gut flora, highlighting the importance of a comprehensive health approach.

Telomeres and Longevity: Unveiling the Gut Microbiome Connection( Part 8/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 30 Jan 24
🏥 Health & Wellness Aging Microbiome Lifestyle Nutrition
  1. Telomeres, the protective caps on chromosomes, shorten with cell division and accelerated attrition is linked to age-related diseases.
  2. The gut microbiome's health and diversity influence telomere integrity, impacting the rate of cellular aging.
  3. Diet, lifestyle choices, and the gut microbiome play significant roles in preserving telomere length and influencing the biological aging process.

Personalizing Your Approach to Prevent Rapid Aging ( Part 11.1/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 05 Feb 24
🏥 Health & Wellness Nutrition Lifestyle Microbiome Aging Performance
  1. The final chapter focuses on individualized approach to slow aging using gut microbiome insights
  2. Personalized medicine tailors health strategies based on gut microbiome for better outcomes
  3. Understanding gut microbiome and tailoring diet & lifestyle leads to healthier aging and improved performance

The Comprehensive Masterclass on Microbes and Sneezes: Unraveling the Hidden Link Between Your Gut Health and Allergies

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 05 Jun 23
🏥 Health & Wellness Gut Health Allergies Microbiome Nutrition Immune System
  1. Certain probiotics during pregnancy can reduce eczema risk in children, C-section births may increase allergy risk, and breastfeeding may protect against allergies.
  2. Growing up on a farm or closer to nature can decrease allergy risk, playing outside reduces allergies, and hand washing dishes can lower allergy rates.
  3. A diet high in processed foods increases allergy risk, while a high-fiber diet may reduce it. Consuming local honey can help manage pollen allergies, and early introduction of peanuts can decrease peanut allergy risk.

The Role of Microbiome in Disease Prevention ( Part 6.1/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 15 Jan 24
🏥 Health & Wellness Microbiome Disease Prevention Immune System Inflammation Metabolism
  1. A healthy gut microbiome helps regulate the immune system, reducing the risk of autoimmune diseases and enhancing the body's ability to fight infections.
  2. Balanced gut microbiota can help regulate inflammation, preventing diseases like arthritis, heart disease, and Alzheimer's.
  3. The gut microbiome influences metabolic health, reducing the risk of conditions such as obesity and type 2 diabetes in older adults.