The hottest COVID-19 Substack posts right now

And their main takeaways
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Top Health Politics Topics

Small Blood Clots May Be at The Root of the COVID-19 Hypoxemia

Harnessing the Power of Nutrients • 0 implied HN points • 22 Apr 20
🏥 Health & Wellness COVID-19 Medical Research Treatment Nutrition Public Health
  1. COVID-19 patients may experience severe lack of oxygen due to small blood clots in the lungs
  2. Mechanical ventilation may not always be necessary for COVID-19 patients as their lung function can be preserved but still experience low oxygen levels
  3. Inflammatory reactions in the lungs of COVID-19 patients might lead to increased blood clot formation, impacting oxygen delivery

Can the Anti-Parasite Medication Ivermectin Treat COVID-19? Probably Not

Harnessing the Power of Nutrients • 0 implied HN points • 17 Apr 20
🏥 Health & Wellness Medication COVID-19 Research Safety
  1. Ivermectin may not be effective in treating COVID-19 based on research findings in isolated cells versus actual blood concentrations needed for effectiveness.
  2. Sustaining the necessary antiviral concentration of ivermectin in the blood for 48 hours is not feasible with current dosing regimens and could lead to unsafe levels of the drug.
  3. It is crucial to rely on verified medical advice and research when considering treatment options for COVID-19, as unsubstantiated approaches like ivermectin may pose risks without proven benefits.

COVID-19 and The Smoking Paradox

Harnessing the Power of Nutrients • 0 implied HN points • 16 Apr 20
🏥 Health & Wellness COVID-19 Research
  1. Smokers diagnosed with COVID-19 are more than twice as likely to develop severe and life-threatening cases, likely due to increased ACE2 expression in the lungs.
  2. The lower prevalence of smokers among COVID-19 patients in studies compared to the general population may be linked to reasons such as smokers avoiding medical treatment, less participation in research, and potential protective effects of smoking against initial infection.
  3. High ACE2 expression may be a liability in disease progression, potentially accelerating viral replication despite ACE2's protective effects, leading to worsening lung damage and severe outcomes.

The Case Against Hydroxychloroquine Grows Stronger

Harnessing the Power of Nutrients • 0 implied HN points • 15 Apr 20
🏥 Health & Wellness COVID-19 Study Inflammation Side Effects
  1. Recent studies show that hydroxychloroquine may not be effective in treating COVID-19, despite initial hype.
  2. Hydroxychloroquine did not impact viral clearance or symptom relief in patients, based on study results.
  3. Potential side effects of hydroxychloroquine, including heart rhythm abnormalities, raise concerns about its safety in severe COVID-19 cases.

New Data Suggesting the Open Air Is Safe During a COVID-19 Outbreak

Harnessing the Power of Nutrients • 0 implied HN points • 14 Apr 20
🏥 Health & Wellness COVID-19 Hygiene Social Distancing
  1. Study on the Diamond Princess Cruise Ship suggests that COVID-19 does not travel far in the air, supporting the safety of being outdoors with proper distancing and hygiene measures.
  2. The research showed that transmission mostly occurred in close quarters on the ship, emphasizing the importance of avoiding mass gatherings.
  3. Fresh air and sunlight have benefits; going outside is safe as long as social distancing is maintained, helping reduce stress and improve well-being.
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Can Cats and Dogs Get COVID-19? An Emerging Controversy

Harnessing the Power of Nutrients • 0 implied HN points • 09 Apr 20
🏥 Health & Wellness Animals COVID-19 Research Infection Prevention
  1. Experimental studies suggest young adult cats can get mild infections and spread the virus, while kittens can get very sick. Dogs show minimal vulnerability to infection under direct inoculation conditions.
  2. Research in Wuhan suggests about 14% of cats in pet hospitals and animal shelters got infected. Exposure to infected owners may lead to more effective antibodies in cats.
  3. A study involving cats and dogs in close contact with COVID-19-confirmed owners showed minimal signs of infection, despite sharing living spaces. Further research is needed to understand transmission and susceptibility in pets.

If You Lose Your Sense of Smell or Taste, What Are the Chances You Have COVID-19?

Harnessing the Power of Nutrients • 0 implied HN points • 07 Apr 20
🏥 Health & Wellness COVID-19 Symptoms Research Prevention Nutrition
  1. Losing the sense of smell or taste may indicate a 61.7% likelihood of having COVID-19, compared to the 5.3% predicted by flu-like symptoms.
  2. Preprints, which are studies not yet peer-reviewed, are crucial for rapidly evolving diseases like COVID-19. They provide valuable information quickly.
  3. Symptoms like loss of taste or smell may have a predictive value for COVID-19, although caution is advised due to study biases and varying rates of symptom occurrence.

In COVID-19, the Nose Gets Infected, and The Nerves Get Damaged: Two New Studies [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 03 Apr 20
🏥 Health & Wellness COVID-19 Research Symptoms
  1. Two new studies suggest that COVID-19 infects the nose and causes loss of smell by damaging nerves.
  2. Preprints play a crucial role in providing reliable information about COVID-19 before peer-reviewed publication.
  3. The virus likely infects mucous-producing cells, ciliated cells, and sustentacular cells in the nose, leading to symptoms like anosmia.

Taking Advantage of the COVID-19 Throat Infection Study With Zinc and Copper [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 02 Apr 20
🏥 Health & Wellness Nutrition Prevention Supplements COVID-19 Research
  1. Zinc can inhibit proteins involved in the replication of SARS-CoV in a way that may also work against SARS-CoV-2.
  2. Using zinc acetate lozenges could help prevent rhinoviruses from docking in the nose, mouth, and throat tissue.
  3. Copper, though not a strong viral replication inhibitor, can be toxic to certain coronaviruses on surfaces, making it worth exploring for safe topical delivery to mucous membranes.

ACE2 Explains Why Smoking Leads to Worse COVID-19 Outcomes [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 01 Apr 20
🏥 Health & Wellness COVID-19 Prevention
  1. Smoking is a risk factor for severe COVID-19 outcomes, with smokers having higher ACE2 levels in their lungs.
  2. Smokers have more mucus-producing cells in their lungs, which can lead to increased ACE2 expression.
  3. Quitting smoking can decrease ACE2 expression in the lungs and may be protective against severe outcomes, highlighting the importance of controlling ACE2 levels.

If You Are Sick, What Are the Chances It’s the Coronavirus? [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 01 Apr 20
🏥 Health & Wellness COVID-19 Nutrition Research Guidance Prevention
  1. In places with low reported cases, having a fever, muscle pain, or cough may mean a 5% chance of having COVID-19.
  2. Be prepared in areas with low case numbers for an increase over 2-3 weeks, similar to patterns seen in other regions like New York City.
  3. Consult a physician promptly if you suspect you have COVID-19, and remember this content doesn't constitute medical advice.

The COVID-19 Coronavirus Infects the Throat, Not Just the Lungs [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 31 Mar 20
🏥 Health & Wellness COVID-19 Prevention Research Nutrition Well-being
  1. COVID-19 infects the throat, not just the lungs, suggesting the virus first enters through the nose, mouth, or throat before reaching the lungs.
  2. Initial beliefs that the virus wouldn't infect the upper respiratory tract, like the throat, were challenged by new research findings.
  3. Comparisons to SARS indicate COVID-19 replicates faster in the upper respiratory tract, making it more contagious, before causing severe lung damage.

Can Quercetin or EGCG Reduce the Risk of COVID-19? [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 29 Mar 20
🏥 Health & Wellness COVID-19 Nutrition Supplements Prevention
  1. Both Quercetin and EGCG have shown potential as zinc ionophores
  2. The concentrations needed for Quercetin and EGCG to act as zinc ionophores are far higher than what can be achieved through oral supplements
  3. Quercetin may inhibit a key enzyme of SARS-CoV-2, but further research is needed to confirm its effectiveness in infected cells

Are Chloroquine and Hydroxychloroquine Zinc Ionophores? [COVID-19 Updates]

Harnessing the Power of Nutrients • 0 implied HN points • 28 Mar 20
🏥 Health & Wellness COVID-19
  1. Chloroquine and hydroxychloroquine act as zinc ionophores, bringing zinc into cells.
  2. The concentrations needed for zinc ionophore activity are much higher than those needed to kill the virus, raising doubts about their antiviral effectiveness.
  3. Chloroquine likely kills SARS-CoV and SARS-CoV-2 by increasing endosomal pH and disrupting glycosylation, rather than through zinc ionophore activity.

Can Hydroxychloroquine or Chloroquine Treat COVID-19?

Harnessing the Power of Nutrients • 0 implied HN points • 27 Mar 20
🏥 Health & Wellness COVID-19 Medication Research Nutrition Treatment
  1. Chloroquine and Hydroxychloroquine have shown antiviral activity in vitro but their effectiveness in humans against COVID-19 is uncertain.
  2. Recent trials have not provided clear evidence of the effectiveness of Chloroquine and Hydroxychloroquine in treating COVID-19.
  3. The World Health Organization is conducting trials to test the efficacy of various treatments for COVID-19, including Hydroxychloroquine, but currently, there is no definitive proof of its effectiveness.

A French Trial Suggests Hydroxychloroquine is Promising Yet Risky, but Wasn’t Randomized

Harnessing the Power of Nutrients • 0 implied HN points • 27 Mar 20
🏥 Health & Wellness COVID-19 Nutrition Medication Research Prevention
  1. Hydroxychloroquine showed promising results in reducing virus presence, especially when combined with azithromycin.
  2. The non-randomized trial had significant dropouts and risks associated with the drug.
  3. The lack of randomization makes it difficult to establish a clear cause-and-effect relationship, urging cautious observation instead of quick conclusions.

Thư ngỏ gửi ông Phạm Quang Hiệu

Thái | Hacker | Kỹ sư tin tặc • 0 implied HN points • 30 Jul 21
🌐 International Vietnam COVID-19 Corruption Foreign Relations
  1. The writer highlights a discrepancy between their group, VietBay, and the government's messaging related to fundraising activities during the COVID-19 pandemic.
  2. VietBay operates independently of government influence, focusing on assisting those in need without aligning with official government calls for action.
  3. The letter expresses concerns about corruption in Vietnamese embassies overseas, citing issues such as inflated passport fees and lack of transparency in fundraising.

Thông báo: hội thảo mini về công nghệ truy vết đảm bảo riêng tư

Thái | Hacker | Kỹ sư tin tặc • 0 implied HN points • 18 Apr 20
🕹 Technology Privacy Contact Tracing Livestream Engineering COVID-19
  1. The event discusses privacy-preserving contact tracing technology and its potential impact on public health in dealing with COVID-19.
  2. The livestream features speakers from companies like Apple, Google, and Walmart Labs sharing insights on Bluetooth sensor engineering and the importance of contact tracing.
  3. Participants can interact with speakers by asking questions through the provided link or chatting directly on YouTube during the event.

Vaccine Hesitancy May Be Unfortunate, But It's Hardly Unreasonable

Symbolic Capital(ism) • 0 implied HN points • 15 Feb 22
🏥 Health & Wellness Vaccine Hesitancy Public Health COVID-19 Pandemic response
  1. Vaccine hesitancy is driven by valid reasons like rapid vaccine development, use of new technologies, shifting efficacy claims, and evolving recommendations.
  2. Skepticism towards authorities and public health guidance is fueled by issues like conflicts of interest, data suppression, and inconsistency in messaging.
  3. Most vaccine-hesitant individuals are not staunchly against vaccines but are more concerned with mandates, passport requirements, and coercive pandemic containment measures.