The hottest Inflammation Substack posts right now

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The Drivers of Age-Related Diseases

Ground Truths • 11154 implied HN points • 08 Jun 25
🏥 Health & Wellness Aging Immunology Inflammation Nutrition Lifestyle
  1. Our immune system and inflammation change as we age. This affects our health and can lead to age-related diseases.
  2. New research shows that tracking certain proteins and genetic markers can help predict health issues related to aging. This could help us focus on ways to stay healthier longer.
  3. Lifestyle factors like diet, exercise, and sleep are important for maintaining a strong immune system and reducing inflammation, which can extend our healthy years.

Ivermectin & Fenbendazole Subscribe Success Stories: Prostate Cancer, Inflammation & Gastric Healing

2nd Smartest Guy in the World • 3203 implied HN points • 16 Jan 24
🏥 Health & Wellness Alternative Medicine Cancer Treatment Inflammation
  1. Combination therapy of Ivermectin and Fenbendazole shows promise in treating and preventing cancer
  2. Ivermectin may have anti-inflammatory properties and potential in treating arthritis
  3. Ivermectin could be effective in treating a wide range of stomach conditions

Explaining the "Hospitalization Paradox"

Harnessing the Power of Nutrients • 3494 implied HN points • 19 Feb 22
🏥 Health & Wellness Public Health Vaccination Disease Inflammation Medical Research
  1. The "Hospitalization Paradox" highlights the vaccine's impact on PCR tests and COVID-like illness, creating a statistical anomaly exploited by media and health authorities.
  2. Vaccines may not be clinically useful as they predominantly impact the ability to test negative rather than reducing the severity of illness or hospitalization.
  3. During the waning phase of efficacy, the persistence of a negative test may correlate with undesirable inflammation, spike protein toxicity, autoimmunity, and COVID-like illness.
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How Essential Are the Essential Fatty Acids?

Harnessing the Power of Nutrients • 718 implied HN points • 28 Nov 22
🏥 Health & Wellness Nutrition Deficiency Inflammation Supplementation
  1. Essential fatty acids are crucial for the body, but mainstream texts may have inflated their required amounts and overlooked sources like animal fats.
  2. Polyunsaturated fatty acids do not directly cause oxidative stress, but in certain conditions, they can pose an oxidative liability, potentially leading to oxidative damage.
  3. Consuming omega-3 fatty acids from sources like fatty fish can provide reserve capacity without overdoing it, especially important in specific life stages and conditions.

The Harm of Weight Cycling

Weight and Healthcare • 738 implied HN points • 09 Feb 22
🏥 Health & Wellness Weight Loss Physical health Mental health Inflammation Well-being
  1. Failing at weight loss attempts can have harmful consequences like weight cycling, which is associated with increased inflammation, hypertension, insulin resistance, and higher mortality.
  2. Weight cycling, common in intentional weight loss efforts, leads to adverse health outcomes and psychological distress.
  3. Despite the low success rate and potential harm of intentional weight loss, it continues to be prescribed, highlighting weight bias in healthcare and the influence of the weight loss industry.

Could the COVID Vaccines Mess With Iron Metabolism?

Harnessing the Power of Nutrients • 139 implied HN points • 19 Feb 22
🏥 Health & Wellness Vaccines Inflammation Autoimmune Disorders
  1. Post-COVID symptoms like fatigue and hair loss could be linked to iron metabolism issues and inflammation
  2. COVID vaccines may lead to elevated IL-6 levels which could disrupt iron metabolism in some individuals
  3. Severe cases of Still's disease flare-ups after vaccination highlight extreme disruptions in iron metabolism, potentially causing functional iron deficiency

Releasing Iron in Long-COVID: Copper, Fasting, and Cooling Inflammation

Harnessing the Power of Nutrients • 119 implied HN points • 19 Feb 22
🏥 Health & Wellness Long Covid Iron Fasting Inflammation
  1. Iron may play a role in post-COVID fatigue and hair loss, but indiscriminate supplementation is not recommended. Instead, focus on reducing inflammation, testing iron levels, and supplementing strategically if needed.
  2. Some argue that COVID may lead to cellular iron overload and that copper, not iron, could be the solution. Exploring these contrasting perspectives can help in addressing iron trapped by inflammation.
  3. Consider a holistic approach to releasing iron trapped by inflammatory processes, which may be beneficial for individuals experiencing long-COVID symptoms.

There's Plastic in My Plaque!

Ground Truths • 4 HN points • 06 Mar 24
🏥 Health & Wellness Plastics Cardiovascular Health Inflammation Preventive measures
  1. First study to find micro/nano plastics in atheroma plaque with significant link to poorer health outcomes
  2. Plastics are pervasive and harmful, found in various body tissues and linked to health issues like cancer and premature births
  3. Urgent need to address plastic pollution - focus on reducing single-use plastics and transitioning away from fossil fuels

On Earthing, the Holistic Medicine Trend that's Consumed my Every Waking Thought

Off-Topic • 2 HN points • 15 Sep 23
🏥 Health & Wellness Holistic Medicine Inflammation Research Studies
  1. Grounding, or earthing, involves direct contact with the ground to balance 'energy imbalances.'
  2. Advocates of grounding believe it can improve circulation, immune systems, and regulate circadian rhythm.
  3. Research on grounding has ties to predatory publishers and funding sources, raising questions about the credibility of its health benefits.

Nick Horowski Interviewed Me for the BareNaked Health Podcast About Inflammation, Sleep, and My Personal Health Journey

Harnessing the Power of Nutrients • 19 implied HN points • 08 Aug 16
🏥 Health & Wellness Personal Health Inflammation Sleep
  1. Chris Masterjohn was interviewed by Nick Horowski on the BareNaked Health Podcast about inflammation, sleep, and his personal health journey.
  2. The interview covers topics like resolving inflammation, Vitamin K2, and achieving good sleep.
  3. Listeners can access the full interview titled 'Resolving Inflammation, Vitamin K2, and Great Sleep with Dr. Chris Masterjohn' on the BareNaked Health Podcast website.

Is the “Receptor for AGEs (RAGE)” Really a Receptor for AGEs?

Harnessing the Power of Nutrients • 39 implied HN points • 21 Nov 10
🔬 Science Research Health Inflammation Proteins
  1. The Receptor for AGEs (RAGE) may not actually bind to and activate AGEs as previously believed, leading to a debate in the scientific community
  2. Studies have shown that RAGE is involved in processes like cell proliferation, tissue repair, and immune system function, rather than solely causing inflammation
  3. Deletions of the RAGE gene in mice have shown varied effects, indicating the complex role RAGE plays in the body

JUPITER Trial Emphasizes the Role of Oxidative Degeneration in Atherosclerosis

Harnessing the Power of Nutrients • 19 implied HN points • 02 Jan 09
🏥 Health & Wellness Atherosclerosis Cholesterol Inflammation
  1. The JUPITER trial emphasizes that atherosclerosis is a disease of oxidative degeneration, confirming the link between oxidative damage and heart disease.
  2. The study does not strongly support the widespread use of statins, as the benefits do not justify the costs for most individuals.
  3. CRP plays a role in binding oxidized LDL and facilitating its uptake by the immune system, providing insight into the inflammatory processes of atherosclerosis.

Update on Vitamin D and COVID-19 Using the First Observational Study Released

Harnessing the Power of Nutrients • 0 implied HN points • 24 Apr 20
🏥 Health & Wellness Vitamin D COVID-19 Immune System Inflammation Preventative Care
  1. Maintaining vitamin D levels within 29-34 ng/mL may lead to less severe COVID-19 outcomes.
  2. The relationship between vitamin D and COVID-19 severity is complex and may involve factors like IL-6 levels and lymphocyte counts.
  3. It is important for physicians to test and assess the impact of correcting low vitamin D levels on COVID-19 outcomes.

The Case Against Hydroxychloroquine Grows Stronger

Harnessing the Power of Nutrients • 0 implied HN points • 15 Apr 20
🏥 Health & Wellness COVID-19 Study Inflammation Side Effects
  1. Recent studies show that hydroxychloroquine may not be effective in treating COVID-19, despite initial hype.
  2. Hydroxychloroquine did not impact viral clearance or symptom relief in patients, based on study results.
  3. Potential side effects of hydroxychloroquine, including heart rhythm abnormalities, raise concerns about its safety in severe COVID-19 cases.

My New Wise Traditions Article on Nonalcoholic Fatty Liver Disease

Harnessing the Power of Nutrients • 0 implied HN points • 07 Apr 11
🏥 Health & Wellness Liver health Nutrition Inflammation Health Risks
  1. Fatty liver disease can be caused by nutrient-poor refined foods, choline deficiency, and polyunsaturated oils.
  2. Combining multiple nutritional insults is likely responsible for human fatty liver disease.
  3. Fatty liver is a significant predictor of heart disease risk and greatly impacts overall health.

Wheat: In Search of Scientific Objectivity and New Year’s Resolutions

Harnessing the Power of Nutrients • 0 implied HN points • 05 Jan 11
🏥 Health & Wellness Nutrition Research Diet Inflammation
  1. Consider going gluten-free or Paleo if you have unresolved health problems and suspect gluten sensitivity. It can help you understand your body better.
  2. Be cautious of jumping to conclusions based on incomplete or uncontrolled studies. Verify findings through proper research and controls.
  3. Personal experiences and published literature can complement each other in improving our understanding of health. Sharing results can benefit everyone involved.

Corn Oil, Not “High-Fat,” Causes Inflammation

Harnessing the Power of Nutrients • 0 implied HN points • 13 Jan 10
🏥 Health & Wellness Nutrition Inflammation Research
  1. High-fat diet low in fiber, vitamin D, and calcium can trigger inflammation leading to cancer in the colon, not specifically fat from red meat.
  2. The study mentioned in the article used corn oil, high in omega-6 polyunsaturated fats, which are vulnerable to oxidative stress.
  3. Mice in the study could synthesize their own vitamin C, possibly countering some effects of the high-PUFA corn oil diet, but faced increased oxidative stress and depleted amino acids in their glutathione system.

The Synthesis of Cholesterol and the Activation of Rho

Harnessing the Power of Nutrients • 0 implied HN points • 21 Feb 09
🔬 Science Inflammation Atherosclerosis
  1. Rho activation, linked to stress response, may be more harmful than cholesterol itself
  2. Statins, often known for lowering cholesterol, inhibit not just cholesterol but also important compounds like coenzyme Q10
  3. Inflammation can increase cholesterol levels and activate Rho, impacting nitric oxide synthesis and contributing to atherosclerosis

Boost your Immunity

Are You Okay? • 0 implied HN points • 04 Jun 20
🏥 Health & Wellness Immunity Inflammation Vitamins General Health
  1. Boost your adaptive immune system with a vaccine or by developing neutralizing antibodies after being sick with COVID-19.
  2. Enhance your innate immune system by focusing on your general health through proper sleep, exercise, healthy eating, and stress management.
  3. Taking care of your basic health needs not only helps you fight diseases like COVID-19, but also improves overall health and well-being.

The Role of Microbiome in Disease Prevention ( Part 6.1/11)

Gutsphere - Your Ultimate Guide to Optimal Gut Health • 0 implied HN points • 15 Jan 24
🏥 Health & Wellness Microbiome Disease Prevention Immune System Inflammation Metabolism
  1. A healthy gut microbiome helps regulate the immune system, reducing the risk of autoimmune diseases and enhancing the body's ability to fight infections.
  2. Balanced gut microbiota can help regulate inflammation, preventing diseases like arthritis, heart disease, and Alzheimer's.
  3. The gut microbiome influences metabolic health, reducing the risk of conditions such as obesity and type 2 diabetes in older adults.