The hottest Metabolic health Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

Is Seed Oil Intake Correlated With Bad Health?

Cremieux Recueil • 332 implied HN points • 25 Mar 26
🏥 Health & Wellness Metabolic health
  1. Higher seed oil intake (measured by linoleic acid) is not linked to worse health and is associated with lower long‑term mortality and better markers like lower inflammation and healthier lipids.
  2. Most anti‑seed‑oil arguments rely on mechanistic, animal, or cherry‑picked evidence and are inconsistent; high‑quality human studies and trials don’t support the claim that seed oils are harmful.
  3. Using stronger methods and measurements (plasma biomarkers, propensity matching, doubly‑robust estimation) removes signals of harm and fails to confirm mechanistic worries like raised arachidonic acid, oxidative damage, vitamin E depletion, or clotting—while saturated fat shows worse associations.

Thinking about Menopause?

The Vajenda • 1749 implied HN points • 26 Sep 23
🏥 Health & Wellness Metabolic health
  1. When thinking about menopause, also consider screening for diabetes as it poses unique risks
  2. Diabetes is associated with various health risks like heart disease, kidney disease, and cancer
  3. Screening for diabetes should ideally begin at age 45, with more frequent screenings based on risk factors

Why Are We Getting Fatter? | Part III: Eating Fat Like Never Before

Mind & Matter • 196 implied HN points • 06 Jan 24
🏥 Health & Wellness Metabolic health
  1. The type of fats we are consuming now is different from what our ancestors ate.
  2. Consuming high levels of omega-6 PUFAs while being deficient in omega-3s can promote inflammation and metabolic dysfunction.
  3. Changes in dietary fat consumption trends, such as a shift towards more plant-based fats, have influenced the balance of fatty acids we consume.

New Guidelines for Weight Loss Surgery?

Weight and Healthcare • 379 implied HN points • 23 Nov 22
🏥 Health & Wellness Metabolic health
  1. New guidelines for weight loss surgery have been released by organizations representing those who profit from these surgeries. These guidelines aim to expand the market for weight loss surgeries by lowering BMI thresholds and targeting younger patients.
  2. The guidelines rely on questionable ideas such as pathologizing higher-weight bodies and setting low expectations for weight loss surgery outcomes.
  3. There is a lack of long-term data supporting these new guidelines, raising concerns about the risks and efficacy of weight loss surgeries, especially for children and adolescents.

I Wore a Levels Blood Glucose Monitor So You Don’t Have To. Here’s What I Learned.

Michael’s Newsletter • 78 implied HN points • 06 Jun 23
🏥 Health & Wellness Metabolic health
  1. Timing your meals around exercise can help lower blood glucose levels naturally.
  2. Blood glucose levels dip and stabilize while we sleep, so avoid eating late at night.
  3. Spreading a large meal into smaller portions throughout the day can help keep blood glucose spikes within a healthy range.
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Metabolic Healing?

The Heart Attack Diet • 59 implied HN points • 07 Nov 23
🏥 Health & Wellness Metabolic health
  1. The author has observed a positive change in their metabolism over time, with improvements in temperature regulation and hypo-metabolic symptoms.
  2. Decreasing thyroid medication was associated with a rise in temperature, suggesting a potential link between thyroid dose and metabolic function.
  3. The author suspects that removing PUFAs from fat stores may have contributed to the improvement in metabolism, although uncertainties remain about the exact causes.

The Real Villain Behind America's Obesity: Seed Oils

Who is Robert Malone • 22 implied HN points • 15 Jan 25
🏥 Health & Wellness Metabolic health
  1. Seed oils are linked to obesity because they might harm thyroid function and slow down metabolism. This means they can make it harder for people to maintain a healthy weight.
  2. Unlike sugar, which is often blamed for weight gain, research shows that high consumption of seed oils could be driving people to store more fat, almost like hibernation mode.
  3. It's important to be aware of what we eat; cooking with traditional fats like butter or coconut oil instead of seed oils could help improve health and combat obesity.

Change the Boogey

Are You Okay? • 0 implied HN points • 25 Jul 22
🏥 Health & Wellness Metabolic health
  1. COVID isn't a moral failure; BA.5 is highly contagious, but vaccines and Paxlovid are effective.
  2. Accepting reality is not giving up; focus on what you can change like vaccination status and health.
  3. Prevent ICU admissions by improving metabolic health through diet, exercise, mental health support, and access to quality foods.

Evidence For Vitamin K2

Harnessing the Power of Nutrients • 0 implied HN points • 28 Apr 13
🏥 Health & Wellness Metabolic health
  1. Vitamin K plays a crucial role in blood clotting, which is essential for preventing hemorrhages and supporting critical clotting factors in the body.
  2. Vitamin K is important for controlling calcium distribution in the body, promoting healthy bone mineralization, preventing calcification of soft tissues, like in the heart and blood vessels, and supporting growth.
  3. Having adequate levels of Vitamin K is crucial for heart health, bone health, dental health, kidney health, and even may play a role in metabolic health, hormonal health, and cancer prevention.

The Journey of Veri: How Anttoni Aniebonam’s Vision for Metabolic Health Led to an Acquisition by Oura

The Healthtech Initiative • 0 implied HN points • 20 Dec 24
🏥 Health & Wellness Metabolic health
  1. Anttoni Aniebonam started Veri to help improve metabolic health after facing personal health challenges from a sports injury. His journey turned into entrepreneurship as he sought solutions for himself and others.
  2. Veri grew rapidly, reaching over 50,000 users and logging millions of meals and glucose levels. Their quick success led to a partnership with Oura, driven by user requests for data integration.
  3. After the acquisition, Veri aims to create similar health features within the Oura platform to continue supporting metabolic health. The goal for both companies is to help people live healthier, longer lives.

GLP-1s: The Real Tradeoffs Nobody Tells You About

The Healthtech Initiative • 0 implied HN points • 17 Mar 26
🏥 Health & Wellness Metabolic health
  1. People taking GLP-1s take fewer steps—activity drops on medication days and stays lower for about seven days.
  2. Resting heart rate rises and heart-rate variability (HRV) falls 2–7 days after dosing, indicating a shift in autonomic markers in a potentially concerning direction.
  3. These patterns were consistent across 538 people using a within-person comparison, so they reflect population-level trends captured by wearables rather than isolated outliers, though the analysis is conservative and correlation-only.