The hottest Drug Safety Substack posts right now

Fentanyl poisoning deaths are preventable with a safe nasal spray called Narcan.
Many young people are dying from fentanyl poisoning after consuming laced drugs like Adderall or pain killers.
It's important to educate oneself and others about the dangers of fentanyl poisoning and have naloxone like Narcan on hand to prevent deaths.

The article highlights concerns about the safety and effectiveness of Paxlovid as doctors start to drop it due to drug interactions and research linking it to Covid rebounds and virus shedding.
Pfizer is heavily promoting Paxlovid amidst concerns, transitioning from Emergency Use Authorization to FDA approval at a much higher price, despite struggles to market the drug successfully.
There is a push to stigmatize skeptics of Paxlovid as 'anti-paxxers,' paralleling previous campaigns against alternative treatments like ivermectin.

FDA approval of a drug does not mean it is completely without risks; it means the benefits are deemed worth the risks.
The FDA assesses the risks and benefits of a drug based on the research provided by the pharmaceutical company before granting approval.
When it comes to weight loss drugs, the risk/benefit analysis by the FDA may be skewed due to questionable research around weight and health, leading to a lower safety bar for approval.

Antipsychotic medications can increase the risk of metabolic syndrome and other adverse outcomes in individuals with depression.
Youth treated with higher-dose antipsychotic medications are at risk of increased mortality, especially among vulnerable children.
Treating young adults with high-dose antipsychotic medications can result in significantly more deaths compared to fentanyl, emphasizing the need for better options for vulnerable youth.

The concept of body-size-as-disease is constructed by the diet industry and lacks scientific grounding.
Engaging in intentional weight loss contradicts being a part of the Health at Every Size community.
Research suggests that weight-neutral interventions can offer similar cardiometabolic benefits with fewer risks compared to weight loss drugs.

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