The hottest Toxicology Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

Glyphosate: A story of science, risk, and nuance

Your Local Epidemiologist • 1478 implied HN points • 25 Mar 26
🔬 Science Toxicology
  1. Glyphosate is the world’s most used herbicide, and whether it is harmful depends on the dose and how much someone is actually exposed to.
  2. The science is mixed: very high doses cause cancer in animals, some human studies link heavy occupational exposure to higher risks (including signals for non‑Hodgkin lymphoma), but typical consumer exposures are much lower and the overall population risk remains uncertain.
  3. For everyday life, food residues are generally tiny and not a reason to panic, but farm workers and people living near sprayed fields face higher exposures and should use protective gear and community measures like buffer zones.

Relax, Microplastics Aren’t Killing You

Common Sense with Bari Weiss • 741 implied HN points • 22 Jan 26
🔬 Science Toxicology
  1. Microplastics are everywhere and do pose real ecological risks. But alarmist claims that they are immediately causing major human diseases aren’t supported.
  2. A high‑profile study claiming plastic in human brains used a detection method that can’t reliably distinguish plastic from ordinary fats, so its results are likely false.
  3. Experts have criticized and reversed those dramatic claims, showing we need better methods and more careful interpretation before linking microplastics to serious human health effects.

The Microplastic Concerns Elevate—To the Brain

Ground Truths • 13384 implied HN points • 03 Feb 25
🏥 Health Politics Toxicology
  1. Microplastics are accumulating in the brain and other organs, with much higher levels found in people with dementia. This is raising alarms about their possible effects on health.
  2. Studies have shown that microplastics can affect blood flow in the brain, leading to issues like blood clots. This suggests they could contribute to neurological problems.
  3. To reduce exposure to microplastics, people can avoid plastic packaging and heating plastic items. There's also a need for broader action to cut down plastic production overall.

It’s Not Just Red Dye No. 3. It’s All Our Stuff.

Common Sense with Bari Weiss • 3909 implied HN points • 21 Jan 25
🏥 Health Politics Toxicology
  1. The FDA recently banned Red Dye No. 3 due to concerns about its link to thyroid cancer in animals. It's a small victory, but there are many other potentially harmful additives still being used.
  2. Red Dye No. 3 will likely be replaced by Red Dye No. 40, which also has warnings about its effects on children in Europe. This shows that simply switching one dye for another isn't a true solution.
  3. There is a growing concern that synthetic dyes are just a small part of a larger problem with harmful chemicals in our food and products. It's important for consumers to demand safer options.

Dr. Mike Yeadon's excellent substack posted on LIONESS OF JUDAH MINISTRY, worth every read: "Dr. Yeadon Reveals TOXICITY MECHANISMS in COVID Kill Shots "I have a different yet complimentary point,

Alexander News Network -Dr. Paul Elias Alexander's substack • 1277 implied HN points • 11 Feb 24
🏥 Health & Wellness Toxicology
  1. Dr. Yeadon points out potential toxicity mechanisms in COVID vaccines based on his toxicology expertise and industry experience.
  2. Different mechanisms of toxicity in COVID vaccines were identified, which wouldn't be overlooked in typical drug development processes.
  3. Open letter to the European Medicines Agency highlighted concerns about potential harms from mass vaccine administration, with subsequent validations.
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The Botanical World is Full of DMT 🌱

Tripsitter • 159 implied HN points • 28 Aug 23
🔬 Science Toxicology
  1. DMT is common in nature, found in various plants, animals, and sea sponges.
  2. Our body efficiently disables DMT from taking effect with the enzyme monoamine oxidase (MAO).
  3. Plants like Acacia, Yopo, and Giant River Reed contain DMT and related tryptamine alkaloids used in rituals and cultural practices.

Glyphosate - Drying Agent and Herbicide for Soy and Wheat and its Potential Health Impacts

Molecular Spectacular • 168 implied HN points • 13 Dec 24
🏥 Health Politics Toxicology
  1. Glyphosate, a common herbicide, has been linked to health risks like increased cancer risk and endocrine disruption. Many studies suggest a troubling connection between glyphosate levels in humans and serious health issues.
  2. Soy protein consumption is strongly connected to higher levels of glyphosate's byproduct, AMPA, in urine. This indicates that what we eat can affect how much of these chemicals we accumulate in our bodies.
  3. There are hints that glyphosate might disrupt gut health, which could impact digestion of gluten. This might be related to rising gluten allergies, especially in sensitive populations like infants.

SNT: Frequently asked questions.

Gordian Knot News • 95 implied HN points • 02 Mar 25
🔬 Science Toxicology
  1. The SNT model divides radiation exposure into daily doses for better tracking of cancer risk. This helps in understanding how each day's exposure can affect long-term health.
  2. SNT is considered conservative in its estimates, as it tends to predict higher cancer risks compared to other models. This is seen as useful for safety regulations.
  3. There is resistance to SNT in the scientific community, with many experts favoring a different model called LNT. This makes it challenging to implement a new standard for evaluating radiation risks.

The end of lead

The Works in Progress Newsletter • 15 implied HN points • 03 Jul 25
🏥 Health Politics Toxicology
  1. Lead exposure has serious health risks, especially for children, causing problems like high blood pressure and cognitive issues.
  2. Efforts to reduce lead in environments, like banning leaded gasoline and paint, have made significant progress but there are ongoing challenges in poorer countries.
  3. We already have solutions to eliminate lead exposure; we just need to implement them globally, especially by regulating sources like cosmetics and battery recycling.

Phthalates, Toxic Plastic Additives, are Everywhere: What’s the Acceptable Limit?

Molecular Spectacular • 43 HN points • 23 May 24
🏥 Health Politics Toxicology
  1. Phthalates are harmful chemicals used in many plastics and can end up in our food. They are found in everyday items like toys, shower curtains, and even cosmetics.
  2. Health experts warn that phthalates can disrupt our body's hormones, leading to various health issues, especially for children. This includes risks to their growth, metabolism, and reproductive health.
  3. Even though we're not consistently above the safe limits for phthalate consumption, studies show we're getting close. It's important to be aware of our daily exposure to these chemicals.

Low Level Chronic Glyphosate Harms in Fetal Development and Reproductive Toxicity

Who is Robert Malone • 16 implied HN points • 16 Nov 24
🏥 Health Politics Toxicology
  1. Low levels of glyphosate, a common herbicide, may harm fetal development and reproductive health. This means that people trying to conceive or expecting a baby should be cautious about glyphosate exposure.
  2. Glyphosate is found in many processed foods and conventional crops, increasing the chances of consuming it without knowing. Choosing organic foods can help reduce exposure to this chemical.
  3. There is growing scientific evidence linking glyphosate to various health issues, including reproductive harm. This highlights the importance of awareness about the potential dangers of everyday food choices.

Can We Filter PFAS Forever Chemicals from Water?

Molecular Spectacular • 3 HN points • 11 Aug 24
🔬 Science Toxicology
  1. PFAS are harmful chemicals that can stay in our bodies and the environment for a long time. There are two types: long-chain and short-chain, both of which are linked to health risks.
  2. Filtering PFAS from water is challenging because existing methods can't completely remove these chemicals, especially the short-chain ones. Currently, a combination of techniques is often needed to get better results.
  3. The EPA has set strict limits for PFAS levels in drinking water, but many water systems still exceed these limits. This highlights the urgent need for effective filtration solutions.

Does Reverse Osmosis Filtered Water Require Remineralization?

Molecular Spectacular • 2 HN points • 29 Sep 24
🏥 Health & Wellness Toxicology
  1. Drinking water that is too pure, like reverse osmosis water, can lead to mineral deficiencies. It can wash away essential minerals in your body, which might cause health problems over time.
  2. It's best to remineralize reverse osmosis water before drinking. This means adding back healthy minerals like calcium and magnesium that the filtering process removes.
  3. If local water sources are contaminated, using reverse osmosis water might be safer, but it's still important to remineralize it to ensure you're getting the necessary nutrients.

What Can Modern Toxicology Tell Us About Food Toxins and Food Intolerances?

Harnessing the Power of Nutrients • 0 implied HN points • 30 Dec 10
🏥 Health & Wellness Toxicology
  1. Modern toxicology distinguishes between intrinsic and idiosyncratic adverse reactions to drugs, showing how some drugs are toxic in high doses for everyone, while others like acetaminophen can become toxic based on individual susceptibility.
  2. Food toxicities and intolerances also involve intrinsic toxicity of foods and individual susceptibility factors like nutritional status, intestinal flora, genes, and immunological reactions.
  3. Factors affecting food toxicity include proper food preparation, genetic variations, intestinal flora, nutrient status, and immunological responses - all of which impact the toxicity of various foods.