The hottest Infectious Diseases Substack posts right now

And their main takeaways
Category
Top Science Topics
Who is Robert Malone β€’ 18 implied HN points β€’ 21 Dec 24
  1. Bird flu mainly affects birds and is not closely related to the seasonal flu that humans get. Human cases are very rare and usually mild, often occurring through close contact with infected birds.
  2. There are plans for new mRNA vaccines to combat bird flu, but many believe the government is overreacting to the threat. Testing and vaccination rollouts are likely to increase, affecting poultry and dairy farmers.
  3. The focus should be on improving farming practices and healthy lifestyles rather than on mass vaccination. Our immune systems need exposure to various pathogens to stay strong, and natural nutrients like vitamins D and magnesium are essential.
Your Local Epidemiologist β€’ 1421 implied HN points β€’ 14 Feb 23
  1. Katelyn Jetelina took a break from newsletter writing this week to work on an emergency with the World Health Organization in Turkey.
  2. A paid subscription to YLE goes beyond commenting powers, as it enables advocacy for necessary change, implementation during emergencies, and saving lives through evidence-based actions.
  3. The subscription also supports advocating for change, implementing changes during emergencies, and saving lives with evidence-based approaches.
Force of Infection β€’ 54 implied HN points β€’ 14 Oct 24
  1. Covid-19 cases are decreasing across the country, with many states reporting low activity, especially in the Western region.
  2. Norovirus is on the rise, particularly in the South, and it can cause stomach pain and vomiting. Good hand hygiene is important to prevent its spread.
  3. Colds and respiratory viruses are becoming more common as the cold season starts, so it's important to stay vigilant about hygiene and health.
Asimov Press β€’ 270 implied HN points β€’ 13 Feb 24
  1. Phage therapy, using bacteriophages to combat drug-resistant infections, has seen renewed interest but faces challenges in scaling up due to the specificity of phages and the complexity of creating effective treatments.
  2. High-tech advancements like AI and synthetic biology offer potential solutions by predicting phage-host relationships and synthesizing phages for personalized treatments, aiming to overcome logistical and regulatory hurdles.
  3. The burden of antimicrobial resistance is predicted to impact low-income countries the most, highlighting the need for affordable, accessible phage therapies that can be used to prevent the spread of bacterial diseases in global health crises.
Asimov Press β€’ 96 implied HN points β€’ 21 Jan 24
  1. Human challenge trials have been used for centuries to deliberately infect individuals with pathogens for research purposes, such as testing vaccines and treatments.
  2. The rising popularity of challenge trials can be attributed to ethical reforms, development of solid challenge models, and the ability to safely and effectively test vaccines for various diseases.
  3. Challenge trials have drawbacks, including recruitment challenges, underpayment of participants, and difficulty in quantifying overall impact.
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Force of Infection β€’ 94 implied HN points β€’ 22 Jan 24
  1. Influenza-like illness activity decreased across all age groups and regions, with improvements in hospitalizations as well.
  2. COVID-19 activity is starting to decrease, supported by various indicators like hospitalizations and test positivity.
  3. RSV trends are showing improvement with a decrease in positivity rates, especially in vulnerable age and ethnic groups.
Force of Infection β€’ 59 implied HN points β€’ 19 Feb 24
  1. Influenza-like illness (ILI) activity has increased in various age groups and regions, with over half of the country affected. However, emergency department visits for influenza are declining.
  2. National Covid-19 hospitalizations are declining in some regions, but there is a resurgence in the South. Overall, the situation is complex with variations across different states.
  3. RSV test positivity is decreasing nationally, but the West and Midwest still have lingering activity. Seasonal coronavirus activity is high, and norovirus remains a concern.
Steve Kirsch's newsletter β€’ 10 implied HN points β€’ 12 Jan 25
  1. Getting vaccinated three or more times may increase your chances of getting infected compared to not getting vaccinated at all. It's surprising to see that more vaccines do not necessarily mean better protection.
  2. The biggest difference in infection rates was seen when people went from being unvaccinated to vaccinated. That change had the most impact.
  3. The numbers showing infection rates were consistent and validated against other surveys, suggesting a trend worth noting. It’s good to examine these findings critically.
Joshua Gans' Newsletter β€’ 19 implied HN points β€’ 10 Mar 21
  1. Covid-19 was not truly a black swan event despite its extreme consequences, as a global pandemic was predictable based on historical precedent and scientific consensus.
  2. Several unexpected positive outcomes emerged during the pandemic, such as minimal surface transmission, limited spread outdoors, and the rapid development of effective vaccines.
  3. The pandemic's string of good luck should serve as a reminder of the unpredictability and potential severity of future global infectious disease events, urging caution and preparedness.
Joshua Gans' Newsletter β€’ 19 implied HN points β€’ 21 Oct 20
  1. Consider testing at the desk instead of at the door to reduce operational challenges and costs, though it comes with the risk of letting infectious individuals into the space
  2. Testing at the desk may lead to fewer infections if it can be done more frequently than testing at the door, highlighting the importance of cost-benefit analysis in testing strategies
  3. Exploring various testing strategies, including combinations of at-the-door and at-the-desk testing, can provide a system with lower cost and less risk in managing infections
Joshua Gans' Newsletter β€’ 19 implied HN points β€’ 19 Oct 20
  1. Knowing the viral load of infected individuals can assist in understanding the infection's stage and progression.
  2. Ct scores from PCR tests can provide critical data for pinpointing viral infection cycles and determining treatment timing.
  3. Recording and utilizing Ct scores from widespread testing can help map virus dynamics at a population level and enhance understanding without relying solely on time series data.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 04 Nov 20
  1. Achieving herd immunity through infection can be a challenging policy due to individual behaviors impacting the rate of infection.
  2. To accelerate the spread of Covid-19 for herd immunity, potential strategies include mask prohibitions, creating situations for people to congregate indoors for extended periods, and avoiding widespread testing.
  3. Implementing unconventional and counterintuitive measures like not announcing vaccine progress, encouraging large gatherings such as political rallies, or subsidizing risky activities could be attempts to expedite herd immunity.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 17 May 21
  1. Infectious disease experts have been following a rule of thumb that particles larger than 5 microns fall to the ground, affecting how they understand virus transmission.
  2. The SARS-CoV-2 virus is about the same size as other viruses considered to be transmitted by droplets, leading to assumptions about its spread.
  3. There is a call for a scientific audit in the field of infectious diseases to review what is known and ensure information is up-to-date.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 21 Aug 20
  1. Testing sewage for the novel coronavirus can help in early detection of outbreaks before they spread widely.
  2. Analyzing sewage can provide valuable information about the presence of infectious diseases in a population, and monitoring waste patterns could lead to new public health insights.
  3. Challenges in using sewage testing for surveillance include factors like rainwater affecting the virus presence, variations in viral material survival, and the need for careful data interpretation.
Are You Okay? β€’ 0 implied HN points β€’ 28 Jun 21
  1. People enjoy autonomy and want positive affirmations in decisions regarding health recommendations.
  2. It's important to understand that eradicating COVID-19 completely is impossible, but controlling it is feasible through vaccination and other preventive measures.
  3. The key to moving forward in this new era is through vaccinations, staying updated on health screenings, and being aware of the measures needed to control COVID-19.
Harnessing the Power of Nutrients β€’ 0 implied HN points β€’ 07 Apr 15
  1. Cod liver oil may have played a role in the decline of measles mortality historically.
  2. Research suggests that cod liver oil may have impacted measles and other infectious disease mortality rates.
  3. Exploring the historical use of cod liver oil could provide insights into combating infectious diseases.
Joshua Gans' Newsletter β€’ 0 implied HN points β€’ 06 Apr 22
  1. When your Covid symptoms abate, you're likely still infectious. Consider "test to leave" or wear a mask after feeling better.
  2. Even after recovering from a cold or flu, continue to wear masks to reduce the spread of illnesses.
  3. With endemic Covid, it's crucial to focus on post-symptomatic measures rather than blanket requirements on asymptomatic individuals.
News from Those Nerdy Girls β€’ 0 implied HN points β€’ 17 Feb 23
  1. To stop the spread of Norovirus, use bleach, wash hands, avoid sharing, close the lid, and stay home if possible for two days.
  2. Norovirus is highly contagious and causes symptoms like vomiting, diarrhea, fever, headaches, and fatigue.
  3. Key tips to prevent Norovirus spread: clean with bleach, wash hands thoroughly, avoid sharing items, close the toilet lid, and stay home to recover and prevent further spread.