The hottest Instruments Substack posts right now

And their main takeaways
Category
Top Music Topics

Prelude no. 1 in C major---music you should know by name

Disaffected Newsletter • 1099 implied HN points • 22 Jun 24
🎶 Music Classical Composition Theory Instruments Performances
  1. Bach's Prelude no. 1 in C Major is a beautiful and well-known piece of music that many people recognize, even if they don't know its name.
  2. The piece is part of a collection called the Well-Tempered Clavier, which showcases different musical keys and tuning systems.
  3. You can hear similarities between Bach's Prelude and the song 'Don't Cry for Me Argentina', showing how classical music influences modern songs.

Another Nanopore: PolySeq

ASeq Newsletter • 14 implied HN points • 16 Feb 25
🔬 Science Biotechnology Genomics Research Innovation Instruments
  1. PolySeq is creating a new DNA/RNA sequencing tool similar to the Oxford Nanopore. It aims to improve how we sequence genetic materials.
  2. The device weighs 1.5 kilograms and can handle 2560 wells or pores. This design helps it generate a lot of data in a short time.
  3. PolySeq plans to produce 15 to 20 gigabytes of data in just 48 hours, making sequencing faster and more efficient.

My 60 Favorite Nonesuch Albums (Part 2 of 3)

The Honest Broker • 3989 implied HN points • 23 Feb 24
🎶 Music Albums Artists Genres Instruments Songs
  1. Nonesuch Records is a unique label that focuses on nurturing creative work and high-quality music rather than just commercial success.
  2. Ted Gioia shares his favorite Nonesuch albums, showcasing a range of artists and eclectic music genres.
  3. Artists like Emmylou Harris and Lake Street Dive found creative freedom and success after joining Nonesuch Records.
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A Tale of Three Guitars

So Here’s a Thing • 1061 implied HN points • 22 Apr 23
🎶 Music Instruments Memories Skill development Music genres
  1. The author recalls acquiring three guitars over a span of forty years, each holding sentimental value and marking different stages in their life.
  2. The first guitar, bought in Moscow in 1978, was a humbling but cherished possession with flaws yet served as a valuable training ground for the author's musical journey.
  3. The most recent guitar, a Martin 000-15M, was a significant gift from the author's late father, embodying warmth and richness in sound that has enhanced the author's musical experience.

The Fazioli Edition

Why is this interesting? • 542 implied HN points • 12 Mar 24
🎶 Music Musicians Instruments Luxury Recording
  1. Nick Cave's pandemic-recorded album 'Idiot Prayer' showcases the unique and poignant sound of the Fazioli piano.
  2. Fazioli pianos are luxury instruments crafted in Italy, known for their exceptional tonal range and precision.
  3. Each Fazioli piano takes three years to build, reflecting the brand's commitment to combining physics, technology, and artistry.

How do we know what 21 degrees C means?

The Newsletter of (Not Quite) Everything • 452 implied HN points • 27 May 23
🔬 Science Measurement Instruments History
  1. Temperature measurement has a long history and was viewed differently in ancient times.
  2. Gradual advancements in creating reliable thermometers involved changing materials and introducing numerical scales.
  3. The meticulous work of individuals like Daniel Gabriel Fahrenheit and Jean-Andr de Luc contributed to establishing standardized temperature scales.

Zakir

Get Down and Shruti • 14 implied HN points • 27 Dec 24
🎶 Music Classical Fusion Performance Collaboration Instruments
  1. Zakir Hussain was a master tabla player known for blending various music styles. He mixed Hindustani classical music with other genres like jazz and rock, creating a unique sound.
  2. His upbringing was unique because he received support from his family, including his mother and wife, to explore different musical paths. This openness allowed him to learn from diverse musical backgrounds and artists.
  3. Zakir's concerts were not just performances; they were experiences. He had a special way of connecting with audiences, making them feel engaged, whether he was playing solo or with other musicians.

🎷Brad, Terry, Herbie Mann, and All That Jazz: Improv Reflections on the Uniquely American Music🎺🎶

Front Row & Backstage • 353 implied HN points • 03 Jul 23
🎶 Music Jazz Improvisation Instruments Artists Performances
  1. Jazz can be a rich experience with different interpretations from various artists.
  2. Listening to jazz involves focusing on individual instruments and appreciating the interplay.
  3. Jazz requires musicianship and expertise to navigate through improvisation within a structured framework.

The PacBio Vega - More Tech Details

ASeq Newsletter • 21 implied HN points • 07 Nov 24
🕹 Technology Engineering Biotechnology Research Instruments Computing
  1. The PacBio Vega is designed for small labs and minimizes downtime between runs. Users can load new samples while a run is ongoing, making it efficient.
  2. The technology in the Vega seems to be similar to the Revio but aims to reduce costs, likely making high-quality sequencing more accessible to small research centers.
  3. There's curiosity about how PacBio has managed to incorporate advanced computing power into a compact design, which is crucial for producing quality data without needing expensive equipment.

Nanostring Vendors

ASeq Newsletter • 51 implied HN points • 05 Mar 24
💼 Business Bankruptcy Instruments
  1. The post discusses Nanostring creditors identified in bankruptcy proceedings, indicating a Google document with detailed creditor breakdowns and mentions suppliers of 'Compelling presentations for litigation'.
  2. The focus of interest lies in the technical components used in Nanostring instruments, narrowing down the list significantly.
  3. Access to the full post is restricted to paid subscribers.

Rationalizing The Illumina Instrument Lineup

ASeq Newsletter • 51 implied HN points • 09 Jan 24
🕹 Technology Biotechnology Instruments
  1. Illumina has a variety of sequencing instruments in their lineup, which includes different models and variations.
  2. The cost of production for these instruments varies based on the technology and components used.
  3. Rationalizing the Illumina instrument lineup could involve withdrawing some current models and introducing new, more cost-effective options.

Some Notes On the MiSeq Flowcell

ASeq Newsletter • 29 implied HN points • 27 Feb 24
🔬 Science Instruments Construction Materials Measurements Research
  1. The MiSeq flowcell consists of a plastic outer shell with a glass flowcell that clips open and closed.
  2. Measurements indicate a cover glass thickness of around 150um and a 100um channel height on a 1mm substrate.
  3. Unlike other flowcells, the MiSeq uses an all glass construction bonded with optical bonding material and borosilicate glass apertures.

NextSeq 550 Flowcell Notes

ASeq Newsletter • 14 implied HN points • 29 Feb 24
🔬 Science Research Instruments Materials Optics
  1. NextSeq 550 flowcell has a unique design where the gasket sits on the flowcell interface and the glass is thicker than other instruments, possibly for stability.
  2. The flowcell glass thickness is surprising and might impact the imaging process, requiring specific optics designed for it.
  3. The material of the channel spacer in the flowcell is unknown, leading to curiosity about its composition and potential patent research.

Cello Solo with Piano Arrangement

Variations on a Theme • 0 implied HN points • 27 Aug 23
🎶 Music Instruments Classical
  1. This post provides a list of cello solos with piano arrangements categorized by difficulty levels I to II.
  2. The difficulty levels range from beginner pieces like Bach and Schirmer, to more advanced works by Bartok and Carl Fischer.
  3. The Suzuki Cello School series offers a progressive learning path for cellists from basic to advanced levels.

Roche Nanopore: Instrument Cost

ASeq Newsletter • 0 implied HN points • 27 Feb 25
🔬 Science Biotechnology Genetics Data Analysis Research Methods Instruments
  1. Roche is working on new nanopore sequencing technology, focusing on how much the instruments will cost to produce. Understanding these costs is important for the technology's success.
  2. The nanopore sequencing process involves collecting a large amount of data quickly, which means the data rates are extremely high. This could lead to challenges in storing and processing such vast amounts of information.
  3. Since the raw data volume is so large, it's unlikely that most users will store it all. Instead, they will probably need to focus on analyzing only the most crucial information collected.

Electric Mushrooms and the Circuitry that Loves Them

Cybernetic Forests • 0 implied HN points • 05 Jun 22
🔬 Science Electricity Instruments History Biology
  1. A synthesizer transforms electricity into sound, similar to how a bassoon uses airflow to create music. The path electricity takes in a synthesizer is altered by manipulating the components and circuits.
  2. Electricity is everywhere, and the manipulation of electrical signals is crucial in creating music with synthesizers. Understanding circuits and modules in a synthesizer helps control the direction of electric pulses.
  3. Living things, like mushrooms, emit electrical signals that can be harnessed and interpreted by synthesizers. Electric currents from organisms can be used as control signals, influencing the flow and shape of generated waves.

Some Plugin Testing / Effects Setup

laserllama's blog • 0 implied HN points • 16 Nov 24
🎶 Music Instruments Production Techniques Effects Sound design
  1. There are cool plugins for music production, like CableGuys Snapback, which adds effects just before sounds hit, making transitions smoother. They help make your tracks more interesting without being too overwhelming.
  2. Guitar pedals can be fun to use with synths, giving you a hands-on experience while making music. Setting them up for each synth can be tricky, but allows for greater creativity and spontaneity.
  3. Plugins like PitchMonster can enhance sounds, not just for vocals but also for instruments like monosynths. They offer a lot of control, making it easier to create unique sounds without getting lost in presets.

On the Inherent Subjectivity of Musical and Scientific Instruments

Cybernetic Forests • 0 implied HN points • 19 Jun 22
🔬 Science Music Instruments Communication Research Experimentation
  1. Our perception shapes our understanding, and expanding our tools of perception can lead to new discoveries in areas like science and music.
  2. The use of voltage spikes in mushroom communication can offer insights into creating electronic music using modular synthesizers.
  3. Sound can provide a unique connection to the information and interactions of living organisms, like mushrooms, fostering a deeper understanding of their behaviors.