The hottest Nutrients Substack posts right now

A high-protein diet is essential for muscle health and weight loss, as it helps maintain lean mass during weight loss.
The amount of protein needed to preserve lean mass during weight loss is higher than the standard recommendation, with around 1.3 grams per kilogram being favored.
High levels of protein in the diet can stress the body's requirements for certain vitamins and minerals, leading to various health issues like poor sleep, anxiety, and skin problems.

Certain diets can impact hormonal balance and potentially shorten lifespan if essential nutrients are lacking.
Various diets were studied for their effects on kidney protection, with calorie restriction showing benefits.
Hydrogen sulfide pathways play a role in kidney protection, but the diet impacts may have unintended consequences like affecting hormones and neurotoxicity.

Molybdenum is a powerful, yet often overlooked nutrient that plays a significant role in testosterone production and fertility.
Consuming too much molybdenum can have negative effects on testosterone levels and fertility, so it's crucial to find the right balance.
The interaction between molybdenum, sulfur amino acids, and other nutrients like zinc is vital for optimizing testosterone levels and overall health.

Whole food vitamin C is preferred because it provides important nutrients, but it is not fundamentally different from ascorbic acid.
Plant sources of choline and flavonoids do not have high levels of vitamin C, and the absorption of flavonoids in plants is low.
Synthetic ascorbic acid is not structurally different from natural vitamin C; however, natural sources like whole food supplements offer additional nutrients and benefits.

Vitamin B9, also known as folate, is essential for the health of babies, blood cells, and cognitive function.
Vitamin B9 plays a crucial role in clearing the 'stickiness' out of our minds, among other important functions.
Consider exploring a premium content source for an in-depth understanding of vitamins and minerals like Vitamin B9.

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The Ultimate Vitamin K2 Resource provides comprehensive information, including practical advice, technical explanations, cute infographics, supplement recommendations, and a searchable database of K2 contents in foods.
Understanding how Vitamin K interacts with other nutrients like Vitamins A and D, zinc, magnesium, carbohydrate, fat, and metabolic factors like carbon dioxide and thyroid hormone is crucial for overall health.
Research suggests that Vitamin D toxicity may lead to soft tissue calcification by causing a relative deficiency of Vitamin K, showcasing the importance of balance in nutrient intake.

Acetyl CoA is a key product in the biosynthesis of cholesterol, derived from various energy sources.
Statin drugs hinder the synthesis of mevalonate, which is crucial for generating cholesterol, squalene, and coenzyme Q10.
Understanding the flow chart of cholesterol biosynthesis helps comprehend the creation of vitamin D, bile acids, and steroid hormones.

Cholesterol is composed of a hydrocarbon tail, a ring structure with 4 hydrocarbon rings, and a hydroxyl group. The combination of these regions classifies cholesterol as a sterol, the animal sterol.
Cholesterol is amphipathic because it contains both water-soluble and fat-soluble regions. It travels in the blood via lipoproteins like LDL and HDL.
Cholesterol, although containing a water-soluble region, is not water-soluble enough to dissolve in the blood directly. Instead, it travels in the blood with fats and fat-soluble nutrients.