The hottest Insulin Substack posts right now

Some ants, like Indian jumping ants, can live much longer lives if they become a pseudoqueen. They can live about five times longer than their worker counterparts after winning a duel for queen status.
The lifespan of these ants can actually change based on their circumstances. If a gamergate is placed in a new colony with an active queen, they revert back to being a normal worker with a shorter lifespan.
This interesting case suggests a different relationship between reproduction and lifespan. In these ants, becoming a reproductive figure seems to extend their life instead of shortening it like it does in many other species.

The author realized that consuming heavy cream lattes from Starbucks significantly increased their daily calorie intake, leading to weight loss plateaus.
The experiment highlighted the importance of being mindful of hidden sources of excess calories in the diet, such as the heavy cream lattes.
Insulin levels and types of protein consumed can play a significant role in fat gain or loss, showcasing the complexity of weight management beyond just calorie counting.

Insulin resistance can exist with normal glucose levels, especially after years on a ketogenic diet.
Measuring fasting insulin levels can be a better indicator of insulin resistance than glucose levels.
The Kraft test, which measures insulin response over time after a meal, can provide more insights into metabolic health than traditional glucose tests.

Start with the article 'Where Do Most AGEs Come From?' for an introduction to glycation and AGEs.
Insulin and glucose play important roles in protecting against AGEs and promoting health.
Question the conventional wisdom on AGEs and explore their implications through podcasts and peer-reviewed articles.

Glycation can be driven by the metabolism of protein, carbohydrate, and fat, and insulin protects against glycation from all three sources.
Glycation may serve important physiological roles under conditions of low insulin signaling, indicating it's not inherently a bad process.
Restricting carbohydrates may actually increase glycation instead of decreasing it, suggesting glycation is not a good argument against consuming carbohydrates.

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Sugar and insulin can have underappreciated benefits like acting as antioxidants and potentially contributing to a more youthful appearance.
The relationship between sugar, insulin, and their effects on the body's defense system may be more complex than previously thought.
Considering different perspectives on sugar and insulin can lead to new insights on overall health and wellness.

Move beyond labeling nutritional boogeymen like sugar or saturated fat and aim for a nuanced understanding of their roles in our diets.
Understand the historical context of figures like Ancel Keys, the process of de novo lipogenesis, and the complex relationship between insulin and fat storage when considering dietary villains.
Avoid simplifying complex nutritional concepts and acknowledge the need for a more sophisticated view of nutrition and health.

Biochemistry textbooks may claim that animals cannot convert fatty acids to glucose, but evidence suggests that it is possible under certain conditions.
Acetate from fatty acids can be converted to glucose in a process involving ketogenesis, particularly when high levels of fatty acids flood the liver.
Insulin plays a role in regulating the conversion of fatty acids to glucose by influencing enzyme production, demonstrating a complex network of reactions in the body.