The hottest Biochemistry Substack posts right now

High-pressure freezing method allows larger biospecimens to be imaged with less milling time.
New study maps neurotransmitter expression in the mouse brain, revealing diversity among neuron types.
Advances in neural recording technology now allow for full cortical depth recording in the brain.

Your physiology and biochemistry, not your circumstances, play a key role in determining your potential and performance.
Optimizing recovery is crucial for reaching peak performance, reducing risks of burnout and enhancing physiological resilience.
Personalized approaches that consider unique biochemical and physiological profiles are vital in unlocking individual potential for peak performance.

Specialization is key to the future of AI in 2024.
AI will increase demand for scientists in various specialized fields.
Automation and AI technologies can support scientists in tasks like research, visualization, and prediction.

Yeast, especially in precision fermentation, can be genetically modified to produce a wide range of chemicals, biologics, and medicines by augmenting their genes.
The main challenge in precision fermentation is reducing costs, particularly in the purification process where proteins are separated from complex solutions.
Novel techniques like self-cleaving tags and self-aggregating proteins offer promising solutions for purifying proteins in a cost-effective and efficient manner, potentially eliminating the need for expensive purification methods like column chromatography.

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New microscopy method combines electron microscopy with fluorescence imaging for detailed mapping of cell types, proteins, and synaptic connections in neuroscience.
Memory ensembles in the brain are formed by neurons with high excitability, helping link memories and facilitating memory recall.
Memory engrams exist across multiple brain areas, and bioelectric fields may coordinate memory ensembles distributed in the brain.

Big data can't replace scientific intuition and understanding
Deep understanding is crucial for utilizing scientific findings effectively
Mechanistic insight in scientific journals like Science Signaling is exceptional

Algae bioremediation faces challenges like wastewater treatment methods and integration with existing infrastructure
Positive market signals in 2023 for algae bioremediation including government support and innovative projects
Recent developments include Zanzibar seaweed production increase and Inalve raising €2 million for microalgae production

Enzymes play crucial roles in converting sugar into energy
Hexokinase, Phosphoglucose isomerase, and Phosphofructokinase-1 are key enzymes in the process
The glycolysis pathway involves multiple steps and enzymes to produce ATP