The hottest Cardiovascular Health Substack posts right now

And their main takeaways
Top Health & Wellness Topics
Weight and Healthcare 659 implied HN points 17 Apr 24
  1. The trial data for Semaglutide (Wegovy) for cardiovascular risk reduction was manipulative and lacking in transparency, raising concerns about conflicts of interest and data sharing.
  2. The study demographics were concerning, with a lack of diversity and representation, particularly skewed towards white men, older participants, and those with existing heart disease.
  3. The actual cardiovascular risk reduction with Semaglutide was much lower than claimed, highlighting issues with study design, data presentation, and potential overemphasis on specific demographics in the results.
Ground Truths 7742 implied HN points 24 Sep 23
  1. The expanding GLP-1 drug family shows potential for treating obesity with new triple agonist drugs.
  2. Clinical trials with G-agonists reveal reductions in major cardiovascular events and heart failure symptoms.
  3. GLP-1 drugs have shown promise in treating early type 1 diabetes, cognitive function, alcohol use disorder, and more.
The Skeptical Cardiologist 393 implied HN points 01 Jul 23
  1. A recent study found no increase in cardiovascular risk with testosterone therapy for men with low T levels.
  2. Make sure to confirm low T levels before starting testosterone therapy.
  3. Weight loss and exercise can help alleviate symptoms related to low T without the use of testosterone therapy.
Get a weekly roundup of the best Substack posts, by hacker news affinity:
Are You Okay? 119 implied HN points 12 Sep 22
  1. Menopause hormone therapy can be safe and beneficial when prescribed appropriately, considering individual risks and benefits.
  2. Estrogen doesn't cause breast cancer for the majority of women; the benefits of hormone therapy often outweigh the risks.
  3. Women going through menopause should have open conversations with healthcare providers to make informed decisions about hormone therapy.
Ground Truths 4 HN points 06 Mar 24
  1. First study to find micro/nano plastics in atheroma plaque with significant link to poorer health outcomes
  2. Plastics are pervasive and harmful, found in various body tissues and linked to health issues like cancer and premature births
  3. Urgent need to address plastic pollution - focus on reducing single-use plastics and transitioning away from fossil fuels