The hottest Diagnosis Substack posts right now

And their main takeaways
Category
Top Health & Wellness Topics

Turbo Cancer Leukemia - children from ages 11 to 21 are dying within hours or days of cancer diagnosis (new case: 16 year old Kyle Limper)

COVID Intel - by Dr.William Makis • 3891 implied HN points • 02 May 23
🏥 Health & Wellness Diagnosis
  1. Children aged 11 to 21 are dying within hours or days of being diagnosed with Turbo Cancer Leukemia
  2. A 16-year-old named Kyle Limper died within 24 hours of being diagnosed with leukemia
  3. Kyle Limper's father initially took him to urgent care for back pain after playing basketball

Personality or Pathology

Polymathic Being • 37 implied HN points • 15 Feb 26
🏥 Health & Wellness Diagnosis
  1. Personality traits are real, measurable, and partly inherited, so tools like MBTI or the Big Five can help meaningfully describe how people tend to think and act.
  2. If we throw out personality frameworks, normal differences can get pathologized as disorders, while real personality disorders may be missed or hidden.
  3. Personality tests are imperfect stereotypes but useful when used carefully; they help match people to roles and prevent forcing everyone into the same behavioral box.

Autism diagnoses are rising, yes, but autism, probably not

Just Emil Kirkegaard Things • 923 implied HN points • 09 Jan 24
🔬 Science Diagnosis
  1. Autism diagnoses are increasing due to more liberal diagnostic criteria and shifts in categorization.
  2. There is a trend of decreasing thresholds for autism diagnoses, including reclassifying individuals previously diagnosed with other conditions.
  3. The prevalence of autism is influenced by genetic factors, and options for reducing autism risk may raise ethical questions.

The Autism Surge: Lies, Conspiracies, and My Own Kids

Common Sense with Bari Weiss • 7776 implied HN points • 20 Jul 23
🏥 Health & Wellness Diagnosis
  1. Autism diagnoses in California have increased significantly over the past few decades, with a 50-fold surge in cases over 33 years.
  2. The rise in autism cases cannot solely be explained by better or broader diagnostics, indicating a real and concerning increase in the disorder.
  3. The lack of clear understanding of the causes of autism and the increasing rates point towards a pressing need for better research, support, and services for individuals with autism.
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"Every part of my body hurt"

The Shift With Sam Baker • 1118 implied HN points • 19 Oct 23
🏥 Health & Wellness Diagnosis
  1. Hilary Mantel experienced years of pain before being diagnosed with endometriosis, impacting her fertility.
  2. Exercise was thought to be helpful for menstrual pain, but Mantel's condition led her to feel like she was leaving normal life behind.
  3. The Shift With Sam Baker is a reader-supported publication that offers both free and paid subscriptions.

When will psychiatry invent the barcode?

Wood From Eden • 1344 implied HN points • 04 Dec 24
🏥 Health Politics Diagnosis
  1. Psychiatry has a problem with labels. Many old labels have been removed without clear replacements, making research and understanding harder.
  2. Using numbers instead of words could help describe a person's mental health better. A barcode-like system could show traits and abilities at a glance.
  3. Psychology is subjective and changes over time. Collecting more data through tests can help improve understanding and research in mental health.

What is PCOS?

Ladyparts • 399 implied HN points • 07 Jul 23
🏥 Health & Wellness Diagnosis
  1. PCOS can take many women years or even decades to be diagnosed.
  2. Misdiagnosis can lead to delays in getting the right treatment.
  3. Injuries like broken bones can sometimes be overlooked and need proper diagnosis and treatment.

September 26, 2023 - Latest Data & Long Covid

Frank’s Alabama COVID Newsletter • 176 implied HN points • 26 Sep 23
🏥 Health & Wellness Diagnosis
  1. The latest data shows a decrease in weekly hospitalizations for Covid in the United States, with Alabama experiencing a significant drop.
  2. Alabama's hospitalization rate is still above the national average, but has improved from being ranked 3rd highest to 9th highest in the nation.
  3. Research is ongoing to understand the complexities of long Covid, with one study highlighting the potential role of low cortisol levels in causing profound fatigue.

What the DSM-5 Gets Wrong About Mental Illness

Mind & Mythos • 299 implied HN points • 20 Jan 23
🏥 Health Politics Diagnosis
  1. The DSM-5 categorizes mental illnesses, but it fails to recognize that human traits exist on a spectrum. This means someone might feel varying levels of anxiety on different days, rather than simply being anxious or not.
  2. People often show symptoms of multiple disorders at once, making current diagnostic categories too rigid. For example, two people diagnosed with the same mental illness might have very different experiences and symptoms.
  3. Instead of labeling normal behaviors as disorders, we should focus on a person's distress and functioning. A new model called HiTOP offers a better way to understand mental health by looking at underlying dimensions rather than strict categories.

From Clinic to Genome and Back Again: Cowden Syndrome and PTEN

Holodoxa • 119 implied HN points • 17 Aug 23
🏥 Health & Wellness Diagnosis
  1. Cowden Syndrome, first described in 1963, was named after the patient Rachel Cowden and later found to be associated with the PTEN gene.
  2. The PTEN gene was identified as a tumor suppressor gene responsible for Cowden Syndrome, leading to advancements in genetic diagnosis and personalized medical care.
  3. Cowden Syndrome shows clinical and genetic heterogeneity, with other genes like PIK3CA and AKT1 also implicated, leading to the classification of PTEN Hamartoma Tumor Syndrome for better diagnosis.

Should You Use AI to Diagnose Patients: Foresight and ChatGPT

AI for Healthcare • 78 implied HN points • 20 Mar 23
🏥 Health & Wellness Diagnosis
  1. Using AI for diagnosing patients is not recommended yet due to lack of real-world healthcare testing.
  2. Foresight and ChatGPT are two AI models explored for patient diagnosis, with Foresight showing slightly superior relevancy performance.
  3. AI models like Foresight can be valuable in healthcare for decision support, patient monitoring, digital twins, education, and matching patients to clinical trials.

Addendum to What the DSM-5 Gets Wrong About Mental Illness

Mind & Mythos • 159 implied HN points • 23 Jan 23
🏥 Health Politics Diagnosis
  1. The HiTOP model offers a different way to look at mental health by using sliding scales instead of strict categories for diagnoses. This helps avoid labeling people in a way that might cause stigma.
  2. Unlike the DSM-5, which uses clear diagnoses, the HiTOP focuses on understanding a person’s unique traits and where they fall on various scales. This allows for a more personalized approach to mental health treatment.
  3. There is a connection between the HiTOP model and the Big Five personality traits, suggesting that mental health issues can overlap with broader personality traits rather than being completely separate categories. This creates opportunities to better understand and treat mental health challenges.

Denmark is the ideal country to do vaccine/autism studies because it's almost guaranteed never to find a link

Steve Kirsch's newsletter • 6 implied HN points • 20 Nov 25
🏥 Health Politics Diagnosis
  1. Denmark is seen as a good place for vaccine studies because its diagnosis process for autism is much slower than in other countries. This means many cases are diagnosed later, making it look like there is less of a problem.
  2. The vaccination schedule in Denmark is different, with fewer vaccines given to infants. This might cause developmental issues to show up later, skewing the data in studies that don't account for these differences.
  3. Using Danish data in studies can give a false impression of low autism rates. The delays in diagnosis make it seem like there are fewer cases than there actually are, which could mislead conclusions about the effects of vaccines.

I Am A Sequencing Absolutist

ASeq Newsletter • 80 implied HN points • 06 Oct 23
🏥 Health & Wellness Diagnosis
  1. The author strongly believes in the power and importance of DNA and RNA sequencing in diagnostics.
  2. Many clinicians tend to delay diagnostic tests unless absolutely necessary, relying on common symptoms and tests first.
  3. Despite the potential of advanced genetic testing, clinicians may be hesitant to order tests if there are no clear treatment options available.

My Response to Garrett Smith About My Health

Harnessing the Power of Nutrients • 19 implied HN points • 05 Dec 19
🏥 Health & Wellness Diagnosis
  1. It's important to thoroughly investigate and identify the root cause of health problems, rather than making assumptions without access to all the necessary data.
  2. Symptoms and conditions can have multiple potential causes, highlighting the need for expert analysis and evaluation tailored to an individual's case.
  3. Financial interests should not cloud judgment when evaluating health concerns, and transparency about revenue sources is essential.