The hottest Science Substack posts right now

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Staring At The Tsunami

¡Do Not Panic! • 1788 implied HN points • 21 Aug 23
🔬 Science Psychology Optimism Risk Assessment
  1. Unrealistic optimism can lead to underestimating personal risk and overestimating favorable outcomes.
  2. Our brains may fail to update perceptions when faced with immediate, observable realities, leading to a freeze response.
  3. Depression and neurodiversity may result in a more accurate assessment of risk, providing survival advantages.

4.1 Heaviside, Poynting, & Energy Flow

Fields & Energy • 239 implied HN points • 12 Jun 24
🔬 Science Physics Energy Electromagnetism Theories Mathematics
  1. Poynting and Heaviside explained how energy moves through space, not just through wires. They believed that energy travels through the surrounding medium as it shifts from one spot to another.
  2. They challenged the traditional 'fluid' model of electricity, saying that while current flows through wires, the energy actually flows outside of them. This highlights the importance of electric and magnetic fields in energy transfer.
  3. The debate between the fluid model and the electromagnetic theory showed that although the latter was complex, it provided a more accurate understanding of how energy moves in electrical systems.

Resistors are out to get ya

lcamtuf’s thing • 2652 implied HN points • 28 Nov 23
🔬 Science Electronics Components Circuits Amplifiers
  1. Some components in electronics, like resistors, may not behave exactly as expected especially at high frequencies.
  2. Parasitic impedance and capacitance in resistors can affect circuit performance, especially in applications like feedback loops for operational amplifiers.
  3. Using a two-stage amplifier can help mitigate issues caused by resistor parasitics and ensure better signal integrity.
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4.0 Electromagnetism Comes of Age

Fields & Energy • 259 implied HN points • 05 Jun 24
🔬 Science Physics Electromagnetism Innovation Technology History
  1. Oliver Heaviside improved upon Maxwell's ideas about electromagnetism. He made complex concepts simpler and more useful, opening doors for new technologies.
  2. Heaviside's work helped solve many technical issues with telegraphy, making long-distance communication possible. His innovations changed how electrical signals were sent across wires.
  3. Heaviside created important terms used in electronics today and developed a simplified way to describe energy flow in electromagnetic fields. His contributions are still fundamental in understanding electromagnetism.

The Genetic Time Machine: Neanderthals, genomics and hybridization priors

ideassleepfuriously • 982 implied HN points • 16 Jan 24
🔬 Science Genomics Evolutionary biology Anthropology Genetics Human biology
  1. 200 thousand years of isolation may not be enough for genetic incompatibilities to develop
  2. Genomics has revolutionized evolutionary biology by providing precise insights with massive amounts of data
  3. The mixing of Neanderthal and modern human lineages led to genetic incompatibilities and selection against Neanderthal-origin DNA in modern humans

The Ramanujan Machine

A Piece of the Pi: mathematics explained • 90 implied HN points • 23 Dec 24
🔬 Science Mathematics Technology Artificial Intelligence Research
  1. Srinivasa Ramanujan was a brilliant mathematician known for his unique insights and identities, many of which he discovered in unconventional ways.
  2. The Ramanujan Machine is an AI project that helps generate new mathematical conjectures, making it easier to discover complex equations related to fundamental constants.
  3. The odd double factorial is a useful concept in pairing problems and can be calculated by multiplying all odd numbers up to a certain point, making it easier to understand how to pair off groups.

Neanderthals in the House

Street Smart Naturalist: Explorations of the Urban Kind • 359 implied HN points • 09 May 24
🔬 Science Paleontology Geology Anthropology Urban Nature Natural History
  1. A person found part of a jawbone while visiting their parents' house, and it could be related to ancient humans like Neanderthals. This discovery shows that fossils can be hidden in unexpected places, even in our homes.
  2. Many buildings, like the Getty Museum in Los Angeles, are made from a stone called travertine that has preserved fossils of leaves and other plants. This means you can see ancient life without going to a museum.
  3. Cities like Seattle are full of building stones with hidden fossils, encouraging people to look closer at their surroundings. Exploring urban areas can reveal fascinating pieces of our natural history.

Roche Nanopore Expectation Management

ASeq Newsletter • 29 implied HN points • 23 Jan 25
🔬 Science Genetics Sequencing Biotechnology Research Innovation
  1. The Roche Nanopore sequencer is expected to generate useful sequence data, showcasing its potential in the market. This could help solidify nanopores as a valuable detection technology.
  2. Accuracy is important for applications, but Roche is likely to compete on cost, which could make their technology appealing for various uses. Their position is good for future improvements.
  3. Roche's innovations may lead to significant competition for existing sequencing methods, especially Illumina. The expectations suggest that this could reshape the sequencing landscape.

A Little More Roche Information...

ASeq Newsletter • 21 implied HN points • 29 Jan 25
🔬 Science Biotechnology Genomics Research Innovation Health
  1. Roche is developing a new nanopore sequencer, which is creating some buzz in the scientific community. People are eager to hear more about its features and capabilities.
  2. Alex Dickinson shared his thoughts on Roche's new sequencer after a private briefing. His insights mostly echoed what is already known but added some new expectations for the upcoming announcement.
  3. A few individuals, including the author, have decided to skip NDA previews, allowing them to speculate freely about the product. This has led to informal discussions and excitement about what might be revealed soon.

3.4.1 Ohm's Law

Fields & Energy • 519 implied HN points • 03 Apr 24
🔬 Science Physics Education History Engineering Mathematics
  1. Ohm's Law shows that voltage is equal to current times resistance, which is key to understanding how electrical circuits work.
  2. Georg Simon Ohm faced a lot of criticism during his time for his ideas, but later scientists recognized his important contributions to physics.
  3. Henry Cavendish had discovered concepts similar to Ohm's Law before Ohm, but much of Cavendish's work went unnoticed because he rarely published his findings.

A year in three psychological biases

The Free Mind • 1670 implied HN points • 13 Feb 23
🔬 Science
  1. 2022 was a year filled with extraordinary events and happenings
  2. Weirdness prevailed as seen with the quick resignations and political changes
  3. Consider subscribing to The Free Mind for more insights and access to full post archives

Forest Feed: How Trees Like, Share, & Communicate Through Mycelial Networks 🌲🍄

Tripsitter • 179 implied HN points • 26 Jun 24
🔬 Science Communication Networks Ecology
  1. Forests operate as interconnected organisms, with trees communicating and sharing resources through underground mycelial networks.
  2. The symbiotic relationship between trees and fungi, known as mycorrhizae, plays a vital role in enhancing the forest ecosystem.
  3. Trees use the mycelial network to warn each other of dangers, nourish weaker trees, and even collectively defend against threats like pests.

In cosmology, all our errors lean the same way. The implications are... interesting

The Egg And The Rock • 1650 implied HN points • 09 May 23
🔬 Science Cosmology Astronomy Evolution Theory Research
  1. In cosmology, our errors consistently lead us to underestimate the size and complexity of the universe.
  2. A major flaw in our approach may stem from an unexamined assumption underlying our theories.
  3. Shifting from a universe-as-rock paradigm to a universe-as-egg paradigm may help us better understand the universe's complexity.

Wolverine: The Creature Most Voracious

Street Smart Naturalist: Explorations of the Urban Kind • 239 implied HN points • 06 Jun 24
🔬 Science Animal Behavior Ecology Natural History Mythology
  1. Wolverines are known for their huge appetites and can eat a lot of food at once. They are so gluttonous that they can overeat and need to find narrow spaces to relieve themselves.
  2. These animals have a varied diet and are both hunters and scavengers, eating everything from birds to rodents. They do face tough winter conditions without hibernating, relying on their hunting skills.
  3. People often view wolverines negatively, calling them destructive and cunning. However, they are simply doing what they need to survive in harsh environments and shouldn't be unfairly blamed.

SUPER BUCK MOON 2023

The Lunar Dispatch • 1611 implied HN points • 03 Jul 23
🔬 Science Psychological Effects
  1. Space psychology is a growing field due to long-term space missions potential.
  2. Balancing crew personalities and group dynamics is crucial for successful space missions.
  3. Space sickness poses unpredictable challenges for astronauts, and non-pharmacological treatments are being developed.

Guilt by Association

Doomberg • 6508 implied HN points • 12 Apr 23
🔬 Science Energy Chemistry Geopolitics Natural Gas Oil
  1. Old practices of thrift are now merchandised as 'upcycling.'
  2. Utilizing byproducts from manufacturing and petrochemical industry is both necessary and economical.
  3. High oil prices incentivize more oil drilling, leading to oversupply and lower natural gas prices in the US.

Epistemic Hell

Secretum Secretorum • 1768 implied HN points • 27 Jan 24
🔬 Science Health Physics Medicine Biology Research
  1. Through history, reasoning based on limited information has led to dangerous outcomes, like chronic cyanide poisoning and scurvy.
  2. Some scientific problems, like understanding heredity, have been challenging due to complexity and the need for exceptional datasets.
  3. To escape epistemic hells, radical ideas, serendipity, unlearning prior knowledge, and persistence are vital.

3.5 Summary and Conclusions

Fields & Energy • 259 implied HN points • 29 May 24
🔬 Science Physics Electromagnetism
  1. Maxwell built on the work of earlier scientists to develop his laws of electromagnetism. He connected electricity and magnetism, proving they are linked like never before.
  2. Maxwell emphasized the importance of careful experimentation and having a clear understanding of facts rather than jumping to theories. This approach helped in developing the scientific understanding of electromagnetism.
  3. Innovative ideas often face skepticism, especially from those already established in the field. Acknowledging our limitations and being open to new ideas are crucial for advancements in knowledge.

Science and Serendipity

Dr’s Newsletter • 746 implied HN points • 11 Feb 24
🔬 Science Research Chemistry Toxicity
  1. PhD research can be challenging but can lead to unexpected and serendipitous discoveries
  2. The stability of certain compounds is crucial in preventing toxicity, as observed in experiments with aluminium and silicic acid in fish
  3. Understanding the chemistry behind experimental outcomes is key, as seen in the success of a PhD research project despite initial doubts

Autism diagnoses are rising, yes, but autism, probably not

Just Emil Kirkegaard Things • 923 implied HN points • 09 Jan 24
🔬 Science Autism Diagnosis Mental health Genetics Bioethics
  1. Autism diagnoses are increasing due to more liberal diagnostic criteria and shifts in categorization.
  2. There is a trend of decreasing thresholds for autism diagnoses, including reclassifying individuals previously diagnosed with other conditions.
  3. The prevalence of autism is influenced by genetic factors, and options for reducing autism risk may raise ethical questions.

3.4.7 What is “Free Space?”

Fields & Energy • 299 implied HN points • 15 May 24
🔬 Science Physics Electromagnetism Energy Theories History
  1. Free space is a place where electromagnetic waves can travel without any barriers. It has properties that support these waves, even if it seems empty.
  2. In history, scientists debated whether something could exist in a vacuum. They realized that the vacuum still has physical qualities, leading to the idea of the 'æther' as a medium for wave propagation.
  3. Modern physics shows that even a vacuum is rich in properties, meaning it's not truly empty. We should recognize that there's always something there, supporting energy and wave movement.

MASHUP: Aboriginal Smokeless Nicotine, Quinine & Caffeine Therapy, African G6PD Deficiency

Grey Goose Chronicles • 786 implied HN points • 29 Jan 24
🔬 Science Biology Medicine Genetics Pharmacology History
  1. Aboriginal Australians have a unique way of consuming tobacco with varying effects and health benefits.
  2. Quinine has a rich history in colonial expansion and fighting malaria, while caffeine might hold potential as an antimalarial drug.
  3. Genetic conditions like G6PD deficiency in sub-Saharan Africans show adaptations to malaria, impacting medical treatments and outcomes.

The Goldilocks zone between inbreeding and outbreeding

ideassleepfuriously • 884 implied HN points • 10 Jan 24
🔬 Science Genetics Evolution Human biology Psychology Fertility
  1. The risk of producing abnormal embryos is highest in siblings, lower in first cousins, and lowest in third or fourth cousins.
  2. Inbreeding can lead to shared defective alleles and recessive disorders, causing inbreeding depression.
  3. Outbreeding can lead to genetic incompatibilities and higher rates of miscarriage, causing outbreeding depression.

4.2 Early Models of Electricity

Fields & Energy • 179 implied HN points • 19 Jun 24
🔬 Science Physics Electricity Electromagnetism Models History
  1. Electricity can be understood in two ways: as a fluid traveling through wires or as fields in the space around electric charges. This is still a big question in physics.
  2. Different cultures have unique approaches to explaining scientific concepts. For example, English physicists use hands-on models, while French scientists prefer abstract theories.
  3. Benjamin Franklin was key in shaping the idea that electricity is a single fluid. This foundational concept helps us still today in understanding electricity and electronics.

On RFK Jr., Atrazine and WiFi. Plus a puzzle for you!

An Insult to Intuition • 1454 implied HN points • 26 Jun 23
🔬 Science Technology Medicine Research Biology Physics
  1. Kennedy discussed the potential effects of Atrazine on organisms like frogs and mammals, sparking a debate on environmental toxins.
  2. The story shared analogies between a hypothetical alien civilization and current human societal challenges, emphasizing the importance of humility and balance.
  3. There was a discussion on the perceived health risks of WiFi radiation, highlighting the need for thoughtful consideration and humility in scientific discourse.

How to make use of inductive biases

Mindful Modeler • 219 implied HN points • 04 Jun 24
🔬 Science Machine Learning Interpretability Forecasting Modeling
  1. Inductive biases play a crucial role in model robustness, interpretability, and leveraging domain knowledge.
  2. Choosing inherently interpretable models can enhance model understandability by restricting the hypothesis space of the learning algorithm.
  3. By selecting inductive biases that reflect the data-generating process, models can better align with reality and improve performance.

Mind Viruses

ideassleepfuriously • 746 implied HN points • 30 Jan 24
🔬 Science Demographics Ideology Media Culture
  1. Ideas can spread like viruses from person to person, affecting fitness and function.
  2. The impact of mind viruses can be seen in historical case studies like the Xhosa Cattle-Killing Movement and Brazilian Soap Operas.
  3. Secularism in France and the Bradlaugh-Besant Trial in the UK are examples of how ideologies can shape demographic transitions.