The hottest Medical Research Substack posts right now

And their main takeaways
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Top Health Politics Topics

Why do so many people have ultra-high levels of anti-spike antibodies years after receiving Covid mRNA jabs?

Unreported Truths β€’ 61 implied HN points β€’ 20 Dec 24
πŸ₯ Health Politics Medical Research
  1. Many people are showing very high levels of anti-spike antibodies long after getting COVID mRNA vaccines. It's surprising to see that these levels can remain so elevated for years.
  2. The persistent presence of these antibodies raises concerns about potential long-term health effects. We really don't know yet what this means for people's health.
  3. There are important questions we need to answer about why some people have such high antibody levels. Understanding this is key to figuring out if there are any risks involved.

Accelerating genetic design

The Century of Biology β€’ 272 implied HN points β€’ 26 Mar 23
πŸ”¬ Science Medical Research
  1. Multiple important technological paradigms are converging in the life sciences, impacting life on various scales.
  2. Synthetic biology focuses on designing new genetic circuits to program cells for new tasks.
  3. Using a platform like CLASSIC, genetic circuits can be systematically tested to learn composition-to-function relationships.

VSRF LIVE TONIGHT: Episode 211: Dr. Brian Hooker, PhD, Dr. Karl Jablonowski, PhD and Rick Jaffe, Esq.

Steve Kirsch's newsletter β€’ 1 implied HN point β€’ 22 Jan 26
πŸ₯ Health Politics Medical Research
  1. Peer-reviewed research presented raises serious biological and neurological concerns about cumulative aluminum adjuvant exposure from vaccines in children.
  2. A preprint asserting increased mortality after 2-month infant vaccinations was removed by the platform’s advisory board, and the authors plan to republish the findings on an open-science platform, highlighting concerns about suppression of uncomfortable data.
  3. A newly filed federal RICO lawsuit accuses the American Academy of Pediatrics of financial conflicts and misleading vaccine safety claims, which could have major implications for pediatric policy and public trust.

URGENT: Authors of a big new paper on Covid's heart risks presented its results in a misleading way likely to scare people the paper itself shows are not in danger

Unreported Truths β€’ 64 implied HN points β€’ 11 Oct 24
πŸ₯ Health Politics Medical Research
  1. A recent study found that most people who had Covid do not have an increased risk of heart problems long-term, contrary to scary headlines. It's important for people to have accurate information about their health risks.
  2. The reported increased risks mainly came from hospitalized Covid patients, who are already known to be at higher risk. Most people who were infected but did not need hospitalization had similar heart health to those who never contracted Covid.
  3. The misleading presentation of the study's findings could create unnecessary fear for those who had mild Covid cases. It’s crucial for people to understand their actual risk so they can manage their health appropriately.
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47% of Women Fixed Their Depression by Adding ONE Hormone

Neuro Athletics β€’ 12 implied HN points β€’ 11 Aug 25
πŸ₯ Health & Wellness Medical Research
  1. Many women struggling with depression, cognitive issues, and low libido may benefit from testosterone therapy, as evidenced by a study where 47% reported mood improvements after using testosterone cream.
  2. Conventional treatments like SSRIs often overlook hormone deficiencies that contribute to these symptoms, leading to ineffective solutions for many women.
  3. It's important for women to get their hormone levels tested and to advocate for proper care, including seeking providers who understand hormone therapy, rather than relying solely on diet and exercise.

The LDL Wars: Why Your Cardiologist and Neurologist Should Be Best Friends

Neuro Athletics β€’ 12 implied HN points β€’ 05 Aug 25
πŸ₯ Health & Wellness Medical Research
  1. Lowering LDL cholesterol is important for both heart health and brain health. Keeping your cholesterol low can help protect you from dementia.
  2. There is a lot of strong evidence showing that high cholesterol in midlife increases the risk of dementia later in life. It's crucial to manage cholesterol levels before it becomes a serious issue.
  3. While some people fear the side effects of statins, most do not experience significant issues. Statins can be an effective way to lower cholesterol and may actually help maintain cognitive function.

What miracle cures should we expect from cutting out seed oils?

Experimental Fat Loss β€’ 134 implied HN points β€’ 04 Nov 23
πŸ₯ Health & Wellness Medical Research
  1. Cutting out seed oils can lead to improved skin health and reduced sunburn sensitivity.
  2. Seed oils can easily oxidize and negatively impact cell membranes, potentially causing health issues.
  3. The body can regenerate various cells impacted by seed oils within days to years, leading to potential health improvements over time.

9 studies vaxxed vs. unvaxxed, all published in the peer-reviewed literature, show vaccinated are worse off in every measure

Steve Kirsch's newsletter β€’ 11 implied HN points β€’ 07 Aug 25
πŸ₯ Health Politics Medical Research
  1. All nine studies show that vaccinated children have worse health outcomes compared to unvaccinated children.
  2. The studies cited are peer-reviewed, meaning experts in the field examined the work before publication.
  3. There is a claim that no studies exist that show vaccinated children are better off, raising questions about the evidence supporting vaccination.

Voices in Print

Force of Infection β€’ 28 implied HN points β€’ 06 Mar 25
πŸ₯ Health Politics Medical Research
  1. Patients can offer valuable ideas to improve healthcare based on their personal experiences. It's important for these voices to be heard in medical discussions.
  2. The Voices in Print project connects patients with professional writers to share their suggestions in a clear way. This helps bring patient insights into medical literature.
  3. They are looking for new patient partners who have specific ideas on improving care, and participation in the project is free.

Deliberate Dysentery

Asimov Press β€’ 96 implied HN points β€’ 21 Jan 24
πŸ₯ Health & Wellness Medical Research
  1. Human challenge trials have been used for centuries to deliberately infect individuals with pathogens for research purposes, such as testing vaccines and treatments.
  2. The rising popularity of challenge trials can be attributed to ethical reforms, development of solid challenge models, and the ability to safely and effectively test vaccines for various diseases.
  3. Challenge trials have drawbacks, including recruitment challenges, underpayment of participants, and difficulty in quantifying overall impact.

Analysis of the "Groundbreaking" Multiple Sclerosis Study

Tessa Fights Robots β€’ 10 implied HN points β€’ 31 Jul 25
πŸ₯ Health Politics Medical Research
  1. Recent research on multiple sclerosis (MS) has generated interest but may not be as revolutionary as some claim. It's important to look at the details.
  2. The study connects MS to possible infectious triggers, which opens up new ways to think about neurological symptoms.
  3. Personal insights and discussions can help make sense of complex studies, and sharing perspectives can lead to better understanding.

V-Safe Part 10: Federal Judge Orders CDC to Make Public 7.8 Million V-safe Free-Text Entries Within 12 Months

Injecting Freedom β€’ 91 implied HN points β€’ 11 Jan 24
πŸ₯ Health Politics Medical Research
  1. Federal Judge orders CDC to release 7.8 million V-safe free-text entries for public access.
  2. The decision aims to promote transparency, trust, and accountability in government health data.
  3. Releasing the V-safe data is crucial for independent research and evaluating the safety and efficacy of COVID-19 vaccines.

Not losing fat on Keto/Carnivore? Try eating less protein.

Experimental Fat Loss β€’ 141 implied HN points β€’ 27 May 23
πŸ₯ Health & Wellness Medical Research
  1. Eating high protein might hinder fat loss on Keto/Carnivore diets; consider reducing protein intake.
  2. Popular Keto/Carnivore diets emphasize high protein, but excessive protein intake may not be suitable for everyone.
  3. Moderating protein intake and focusing on adequate fat consumption is essential for maintaining a balanced diet on Keto/Carnivore.

Long COVID – a dystopian game of pinball

Independent SAGE continues β€’ 1 HN point β€’ 01 Aug 24
πŸ₯ Health Politics Medical Research
  1. Long COVID can make people very sick for months or even years after they initially recover from COVID-19. Symptoms like fatigue, brain fog, and breathing problems can really affect daily life.
  2. There isn't a simple test to diagnose Long COVID, which can lead to people doubting its seriousness. However, it's a complex condition that can affect many different parts of the body.
  3. To help prevent Long COVID, it's important to get vaccinated, avoid crowded places, and take care of yourself if you do get COVID-19. Rest and anti-viral medications can help with recovery.

From Maple to Mind Expansion: Unveiling Canada's Psychedelic History with Erika Dyck 🍁

Tripsitter β€’ 19 implied HN points β€’ 14 Jul 23
πŸ₯ Health & Wellness Medical Research
  1. Psychedelics have a long and complex history in Canada, ranging from being viewed as panaceas in the 1950s to being labeled dangerous drugs until recently, but now are being integrated into healthcare for various treatments.
  2. Early Canadian psychedelic research focused on themes of intrigue, sympathy, and addiction, which contributed to a deeper understanding of psychosis, schizophrenia, and treatment for conditions like alcoholism.
  3. Factors like the Thalidomide scandal, countercultural movement, public sensationalism, and loss of scientific naivete contributed to the decline in public support for psychedelics in Canada, leading to prohibitive measures and shifting perceptions of medicine and healthcare providers.

All you need to know about health care this week.

HEALTH CARE un-covered β€’ 79 implied HN points β€’ 24 Jun 22
πŸ₯ Health Politics Medical Research
  1. 41% of Americans have health care debt, showing a huge problem with medical costs in the country.
  2. People with high-deductible health plans often delay necessary treatments due to costs, which can worsen their health outcomes.
  3. Even those with insurance can struggle financially, leading many to seek help from friends or crowdfunding for medical expenses.

Interview with Daniel MacArthur

The Good Science Project β€’ 26 implied HN points β€’ 02 Dec 24
πŸ”¬ Science Medical Research
  1. Daniel MacArthur is working on making genomic medicine fairer for all communities. His research includes studying genetic differences in underrepresented groups to improve health outcomes.
  2. He believes that funding for science needs to be more flexible and stable. This would allow researchers to take risks and pursue long-term projects without the constant pressure of grant deadlines.
  3. MacArthur thinks research organizations should be built specifically to support scientific work. Many current institutions are not designed for research, making it harder for scientists to succeed.

Was DoD the Managing Agency for Operation Warp Speed?

Who is Robert Malone β€’ 19 implied HN points β€’ 08 Dec 24
πŸ₯ Health Politics Medical Research
  1. The Department of Defense (DoD) used a special contracting method called Other Transactional Authority (OTA) to quickly award contracts for the COVID-19 vaccine development. This approach allowed the government to bypass some traditional rules that slow down processes.
  2. There are claims that Pfizer isn't guilty of fraud, but rather provided what the U.S. Government requested under pressing timelines during the pandemic. The argument suggests that the government set the terms and conditions for the vaccine without ensuring thorough oversight.
  3. Because of how OTAs work, the contracts didn't require Pfizer to be as transparent with data, leading to concerns about the safety and effectiveness of the vaccines. This lack of stringent requirements may have contributed to public distrust.

Could DMSO drops restore my vision?

Steve Kirsch's newsletter β€’ 19 implied HN points β€’ 13 Nov 24
πŸ₯ Health & Wellness Medical Research
  1. DMSO might help dissolve blood in the eye, but there's disagreement among doctors about its safety for the retina. Some say it could help, while others warn it might cause more harm than good.
  2. There's evidence that DMSO has been used safely in eye treatments in the past, with some patients seeing improvements, but the effects can vary greatly.
  3. Current treatments for blood in the eye usually include waiting for it to clear up naturally or surgery. DMSO could be a potential game changer, but more research is needed.

A New Mission Statement for NIH--Misguided Semantic Changes?

The Good Science Project β€’ 55 implied HN points β€’ 02 Sep 23
πŸ₯ Health & Wellness Medical Research
  1. The NIH is proposing changes to its mission statement that could impact research investments.
  2. The proposed changes include shifting focus to optimizing health and removing the goal to lengthen life.
  3. The discussion around language and semantics in the mission statement may not have a significant impact on actual medical research outcomes.

Australian excess deaths are highly correlated with the number of booster vaccinations

Steve Kirsch's newsletter β€’ 10 implied HN points β€’ 05 Dec 24
πŸ₯ Health Politics Medical Research
  1. More booster shots lead to more excess deaths. It suggests a possible risk factor with the vaccines.
  2. There seems to be a link between more vaccines and increased COVID cases. This raises questions about their effectiveness.
  3. The study indicates serious concerns about the safety of vaccines, suggesting that some people may have been harmed significantly.

Roche Nanopore: Accuracy

ASeq Newsletter β€’ 7 implied HN points β€’ 28 Feb 25
πŸ”¬ Science Medical Research
  1. Roche's Q39 accuracy system is different from other platforms like Illumina and Oxford Nanopore. It's important to compare them carefully as each has unique metrics.
  2. The average accuracy of different sequencing platforms varies, but Roche doesn't provide clear comparisons. They share limited data about their simplex accuracy.
  3. Understanding the differences in data quality and error rates across platforms is crucial. Factors like read length and error filtering play a significant role in the accuracy of sequencing results.

States Recently Threw Out Millions of Dollars of Unused Masks and Other Pandemic Gear. But the Story is Not What You Think.

Silent Lunch, The David Zweig Newsletter β€’ 23 implied HN points β€’ 02 Feb 24
πŸ₯ Health Politics Medical Research
  1. States threw away millions of dollars worth of PPE that could have still been effective.
  2. Expiration dates on masks and gowns may not accurately reflect their actual effectiveness.
  3. Authority decisions on PPE disposal lack evidence-based analysis and contribute to public health policy concerns.

129 | The Mysterious Case of Bacon Brain | Chocolate Crisis |

The Rotten Apple β€’ 21 implied HN points β€’ 11 Mar 24
πŸ₯ Health & Wellness Medical Research
  1. Downloadable back issues are available for readers to catch up on past content.
  2. Improper handwashing and contaminated food led to a man in the US developing tapeworm larvae in his brain, highlighting the importance of food safety practices.
  3. The chocolate supply chain is facing a crisis due to rising cocoa prices caused by global supply pressures from climate change, impacting chocolate production and potentially leading to product frauds.

Tectonic Therapeutic: Protein Engineering and Fc-relaxin for Hypertension

Axial β€’ 7 implied HN points β€’ 31 Jan 25
πŸ₯ Health & Wellness Medical Research
  1. Tectonic Therapeutic focuses on protein engineering to help treat hypertension. This means they are working on new medical treatments using proteins to effectively lower blood pressure.
  2. Axial invests in early-stage life sciences companies. They are particularly interested in supporting new ideas and inventions that can grow to make a big impact in healthcare.
  3. Support for inventors is a key part of Axial's mission. They aim to help those who are passionate about creating lasting solutions in the life sciences field.

Synthetic integrin antibodies discovered by yeast display reveal Ξ±V subunit pairing preferences with Ξ² subunits

Axial β€’ 7 implied HN points β€’ 31 Jan 25
πŸ”¬ Science Medical Research
  1. New antibodies were created that can specifically block integrins, which are important for cell functions like attachment and signaling. This may lead to better treatments for diseases.
  2. Researchers found that different Ξ² subunits bind preferentially to the Ξ±V subunit in integrins. Understanding these pairings helps explain how integrins work in the body.
  3. The antibodies developed through this study can directly compete with small molecules that normally bind to integrins. This opens the door for more precise therapies in the future.

Creatine and Renal Function

Neuro Athletics β€’ 20 implied HN points β€’ 26 Feb 24
πŸ₯ Health & Wellness Medical Research
  1. Studies show creatine is not harmful to renal function and does not cause serious health risks.
  2. Misconceptions about creatine causing hair loss and baldness are not supported by strong evidence.
  3. It's safe to use creatine in recommended amounts for kidney health, but consulting a doctor is wise, especially for those with kidney issues.

NIH and March-In Rights under Bayh-Dole

The Good Science Project β€’ 18 implied HN points β€’ 21 Feb 24
πŸ₯ Health Politics Medical Research
  1. The debate around NIH's march-in rights intersects with concerns over potentially overpriced pharmaceuticals developed with NIH funding.
  2. Empirical evidence suggests that very few drugs could be subject to NIH's march-in rights due to limited NIH funding directly impacting drug development.
  3. The application of march-in rights under Bayh-Dole is complex legally and practically, with challenges such as potential lawsuits over arbitrary interpretation and limited impact on drug pricing.

Do vaccines cause autism?

Steve Kirsch's newsletter β€’ 7 implied HN points β€’ 17 Dec 24
πŸ₯ Health Politics Medical Research
  1. Vaccines and autism have been debated often, but many experts say there is no link between them. It's important to look at good data and research.
  2. A recent survey found that many families have children with autism, raising questions about what could be causing it. Understanding this issue is really important for families.
  3. The author wants to collect personal stories from families about when their child started showing signs of autism. He believes it's crucial to gather more information in this area.

Year In Review - Long Reads

ASeq Newsletter β€’ 7 implied HN points β€’ 18 Dec 24
πŸ•Ή Technology Medical Research
  1. PacBio faced challenges in the stock market but still aims to provide high-quality clinical genomic sequencing. They are seen as a strong competitor in the long-read space despite financial struggles.
  2. Oxford Nanopore has been active in raising funds but has dealt with internal issues and departures of significant team members. Profitability remains an elusive goal for both them and PacBio.
  3. New competitors are emerging in the long-read sequencing market, including Roche and BGI, who are exploring nanopore sequencing technology. This could shake up the landscape for current players.

Looking for a New NIH Director

The Good Science Project β€’ 29 implied HN points β€’ 17 Mar 23
πŸ”¬ Science Medical Research
  1. NIH Directors historically have had similar backgrounds, typically with PhDs or MDs and extensive academic experience.
  2. Consider expanding the pool of potential NIH Director nominees beyond traditional criteria to include those with diverse backgrounds and experiences.
  3. Look for a potential NIH Director who excels at identifying talent, has broad interests, is open to new ideas, and is willing to push for meaningful reforms.

New Thailand randomized clinical trial shows early treatment with just 2 drugs was 100% effective in eliminating risk of hospitalization from COVID

Steve Kirsch's newsletter β€’ 9 implied HN points β€’ 16 Mar 24
πŸ₯ Health & Wellness Medical Research
  1. A recent Thailand clinical trial showed 100% effectiveness in preventing COVID hospitalizations with a 2-drug combination, in contrast to the 37.5% hospitalization rate with standard care.
  2. The early treatment combination of fluvoxamine and another drug displayed clear benefits in preventing hospitalizations and reducing serious adverse events, unlike the COVID vaccines.
  3. Despite strong evidence and successful outcomes of multi-drug treatments since early 2020, health authorities and organizations like CDC, FDA, and WHO continue to overlook and ignore these effective treatment options.

Acute kidney injury after vaccination: New Zealand government scientists changed their data without explanation

Steve Kirsch's newsletter β€’ 10 implied HN points β€’ 16 Jan 24
πŸ₯ Health Politics Medical Research
  1. The data showed COVID vaccines causing kidney injury, then it mysteriously changed.
  2. Scientists in New Zealand altered their research data without clarifying why.
  3. There was a significant risk of myocarditis after vaccination, which was not openly acknowledged by health authorities.

VSRF LIVE TONIGHT: Episode 164 - White Clot Roundtable!

Steve Kirsch's newsletter β€’ 2 implied HN points β€’ 13 Feb 25
πŸ₯ Health Politics Medical Research
  1. There's a live event about a serious topic involving white fibrous clots in bodies. Many embalmers have reported seeing these clots more often, which is concerning.
  2. Experts will discuss a possible blood test that could help people find out if they're affected by these dangerous clots. It's important for everyone to stay informed about their health.
  3. The event will feature professionals from different fields sharing their insights. This could shed light on the science behind these clots and what it means for our health.