The hottest Medical Research Substack posts right now

And their main takeaways
Category
Top Health Politics Topics

Not losing fat on Keto/Carnivore? Try eating less protein.

Experimental Fat Loss • 141 implied HN points • 27 May 23
🏥 Health & Wellness Nutrition Weight Loss Metabolism Diet Medical Research
  1. Eating high protein might hinder fat loss on Keto/Carnivore diets; consider reducing protein intake.
  2. Popular Keto/Carnivore diets emphasize high protein, but excessive protein intake may not be suitable for everyone.
  3. Moderating protein intake and focusing on adequate fat consumption is essential for maintaining a balanced diet on Keto/Carnivore.
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A New Mission Statement for NIH--Misguided Semantic Changes?

The Good Science Project • 55 implied HN points • 02 Sep 23
🏥 Health & Wellness Public Health Medical Research Advocacy
  1. The NIH is proposing changes to its mission statement that could impact research investments.
  2. The proposed changes include shifting focus to optimizing health and removing the goal to lengthen life.
  3. The discussion around language and semantics in the mission statement may not have a significant impact on actual medical research outcomes.

Acute kidney injury after vaccination: New Zealand government scientists changed their data without explanation

Steve Kirsch's newsletter • 10 implied HN points • 16 Jan 24
🏥 Health Politics Vaccination Public Health Medical Research Government Transparency
  1. The data showed COVID vaccines causing kidney injury, then it mysteriously changed.
  2. Scientists in New Zealand altered their research data without clarifying why.
  3. There was a significant risk of myocarditis after vaccination, which was not openly acknowledged by health authorities.

Looking for a New NIH Director

The Good Science Project • 29 implied HN points • 17 Mar 23
🔬 Science Biology Medical Research Innovation Reform
  1. NIH Directors historically have had similar backgrounds, typically with PhDs or MDs and extensive academic experience.
  2. Consider expanding the pool of potential NIH Director nominees beyond traditional criteria to include those with diverse backgrounds and experiences.
  3. Look for a potential NIH Director who excels at identifying talent, has broad interests, is open to new ideas, and is willing to push for meaningful reforms.

A more equitable AI model for breast cancer risk assessment

philsiarri • 1 HN point • 29 Nov 23
🏥 Health & Wellness AI Diversity Medical Research
  1. Researchers presented a groundbreaking AI model for breast cancer risk assessment that can accurately predict across diverse racial backgrounds.
  2. Traditional risk assessment models showed biases, particularly in non-white populations, due to data derived from predominantly European Caucasian populations.
  3. The AI model outperformed traditional models, achieving consistent accuracy in predicting breast cancer risk across different racial groups.

That time when a bunch of people all agreed to preserve each other's brains

Neurobiology Notes • 1 HN point • 13 Feb 23
🔬 Science Neurobiology Cryonics Brain preservation Medical Research
  1. Mutual autopsy societies in the late 1800s preserved and studied members' brains to advance science.
  2. Brain preservation methods involved using different fixatives like alcohol and formaldehyde as the science evolved.
  3. Members of these societies faced challenges like family resistance and scandal, which offer lessons for today.

5. The perils of the cohort study

Insight Axis • 0 implied HN points • 03 Sep 22
🏥 Health & Wellness Medical Research
  1. Clinical trials based on population averages can lead to injustice for individuals.
  2. Individuals may be affected negatively if interventions are prescribed based on study outcomes.
  3. Current adjustments for confounds may not be sufficient when applying population-based science to complex individuals.

To pay or be paid?

Joshua Gans' Newsletter • 0 implied HN points • 16 Dec 20
🏥 Health & Wellness Vaccine distribution Public Health Medical Research
  1. Economists suggest using prices to address vaccine distribution issues. This includes charging for doses to signal demand and potentially paying individuals to take the vaccine.
  2. There is a proposal to pay individuals to receive the vaccine in order to address low demand. By offering subsidies, it can help close the gap in vaccination rates.
  3. Balancing the approach between paying for priority in vaccine distribution and paying individuals to get vaccinated presents challenges. Complexity arises when trying to incorporate financial incentives into the vaccination process.

(Try To) Make Sense of Long COVID

Are You Okay? • 0 implied HN points • 16 May 22
🏥 Health & Wellness Long Covid Symptoms Mainstream Media Prevention Medical Research
  1. Long COVID symptoms are wide-ranging and may not solely be caused by SARS-CoV-2 infection. They can overlap with other conditions like stress, anxiety, and hormonal imbalances, making it challenging to diagnose long COVID accurately.
  2. The media often sensationalizes long COVID, leading to misconceptions about its prevalence. Studies suggest that post-COVID symptoms are not exclusive to COVID and can be influenced by various factors such as stress, underlying health conditions, and life disruptions.
  3. Preventing long COVID includes vaccination, avoiding high-risk environments, and managing underlying health conditions. Research on antiviral medications and alternative vaccine delivery methods could potentially reduce the risk of long COVID in the future.

Day One Biopharmaceuticals in the spotlight

Boutique Biotech • 0 implied HN points • 02 Mar 23
🏥 Health & Wellness Pharmaceuticals Drug Development Medical Research Patient Care
  1. Late-stage biotech companies have seen increasing value, while earlier stage companies have seen declines.
  2. Day One Pharma is developing a drug for pediatric low-grade gliomas, showing promising results.
  3. Important updates to look for include duration of response, safety profile, and NDA submission for Day One Pharma.