The hottest Innovation Substack posts right now

And their main takeaways
Category
Top Technology Topics

Mercenaries versus Missionaries in the startup world

Respectful Leadership • 163 implied HN points • 14 Jun 25
💼 Business Leadership Startup Innovation Team Building Hiring
  1. In the startup world, it’s important to hire people who are passionate about the mission, known as 'missionaries.' They care deeply about making a difference.
  2. Hiring based on resumes alone isn't enough. It's better to focus on why candidates are motivated and their true potential.
  3. Embracing ambiguity can actually lead to innovative solutions. Startups should encourage working freely without strict guidelines.

America is losing the physical technologies of the future

Noahpinion • 15294 implied HN points • 18 Dec 24
🕹 Technology Electric Vehicles National Security Energy Policy Innovation
  1. America is falling behind in key physical technologies like electric vehicles and renewable energy. This is a big deal for the country's future power and economic success.
  2. The shift in focus towards electrical technologies is often viewed through the lens of climate change rather than national power. This misunderstanding could hurt America's position in global technology.
  3. Countries like China are gaining an advantage in these technologies, which could impact America's leadership in the world. It's essential to prioritize these innovations beyond just climate talk.

The Formula for the Future

Faster, Please! • 1096 implied HN points • 17 Feb 25
🇺🇸 U.S. Politics Regulation Innovation Economy Technology Progress
  1. America's future depends on three key things: strong information processing, abundant energy, and economic freedom. These elements can help society grow and innovate.
  2. Regulatory barriers often slow down progress and innovation. To keep moving forward, it's important to take calculated risks instead of playing it safe.
  3. Embracing technology and overcoming bureaucracy can create a cycle of improvement. More energy and innovation can lead to a better future for everyone.

While the West Hesitates China Marches Forward

The Algorithmic Bridge • 637 implied HN points • 21 Feb 25
🕹 Technology AI Innovation Government Data Globalization
  1. China is rapidly adopting AI technology, using systems like DeepSeek across government operations to improve efficiency and decision-making. This shows their proactive approach to embracing innovation.
  2. DeepSeek has emerged as a competitive AI model that rivals established Western technologies, highlighting China's growing capabilities in the tech sector. China is focused on getting results, not just discussing ideas.
  3. The cultural mindset in China emphasizes efficiency and action, contrasting with the West's tendency to debate and regulate rather than implement. This difference in attitude could impact global technological leadership.

10 Takeaways From Tech’s Biggest News Week of the Year

Big Technology • 3002 implied HN points • 23 May 25
🕹 Technology AI Software Innovation Business Networking
  1. AI models are still getting better with size, but people are also focusing on new algorithms to improve them. This means companies like NVIDIA will continue to thrive for now.
  2. There's a growing belief that algorithm improvements might be more important than just making AI bigger. This might change how we think about developing AI in the future.
  3. AI technology is rapidly evolving, especially in video generation and coding, which could lead to significant advancements and some ethical concerns as it becomes more powerful.
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No More Forms to Fill Out

In My Tribe • 318 implied HN points • 08 Jun 25
🕹 Technology AI Software Education Communication Innovation
  1. Filling out forms is a common part of life, but it often feels outdated. Instead of forms, we could use conversations with AI to make communication easier.
  2. Using AI like Claude, teachers can upload their syllabi and have an interactive conversation to turn their ideas into structured course content. This way, the process becomes more collaborative and flexible.
  3. This new method allows for ongoing adjustments and real-time feedback, leading to a stronger connection between the content and the user's needs. It's not just about filling out information, but working together to create something meaningful.

Biotech

ChinaTalk • 681 implied HN points • 09 Jun 25
🕹 Technology Biotech Pharmaceuticals Innovation Health Research
  1. China's biotech industry has transformed from copying foreign drugs to developing innovative medications that compete globally. This shift shows that they are now making significant progress in drug discovery.
  2. Companies like BeiGene and Legend Biotech have successfully created cancer therapies that are approved internationally, demonstrating China's growing capability in biopharmaceuticals and bringing new options to cancer patients worldwide.
  3. New drugs from Chinese companies like Akeso are showing promise in clinical trials, potentially leading to breakthroughs in cancer treatment. This trend attracts global attention and investments, signaling a bright future for China's biotech sector.

AI Infra Companies Are Coming for Verticals

Enterprise AI Trends • 211 implied HN points • 24 Jun 25
🕹 Technology AI Software Infrastructure Data Innovation
  1. AI infrastructure companies are starting to create their own products for specific industries, which could hurt existing vertical businesses. This trend is called 'infra verticalization.'
  2. These infrastructure firms have a unique advantage because they collect valuable data that helps them see what works best in the market.
  3. The relationship between vertical AI and infra companies is getting tricky as they compete for the same customers and market space.

Huawei Founder on US v China and Basic Research

ChinaTalk • 415 implied HN points • 11 Jun 25
🕹 Technology Research Innovation Policy Economics Development
  1. Basic research is crucial for long-term success. Without it, countries can't make significant advancements and keep up with other leading nations.
  2. There are many challenges in the tech industry, but rather than focusing on the negative, it's important to keep moving forward and adapt. China is making progress through collaboration among its numerous chip companies.
  3. Support for theoretical scientists and researchers is essential. Their work, though often misunderstood and slow to show results, is key to the future development and innovation of the country.

The End of Search, The Beginning of Research

One Useful Thing • 2047 implied HN points • 03 Feb 25
🕹 Technology AI Research Software Innovation Automation
  1. New AI Reasoners can think better and solve tougher problems by producing thinking steps before answering. This makes them more effective than earlier chatbots.
  2. AI agents are being developed to autonomously pursue goals, but they currently face limitations when tackling complex tasks. They show promise with narrow, task-specific applications.
  3. OpenAI's Deep Research represents how specialized AI can work like a human researcher by engaging deeply with academic topics, paving the way for significant advancements in research efficiency.

Problems Sublime solves—at least for me

The Sublime Newsletter • 554 implied HN points • 19 Oct 24
🕹 Technology Internet Software Productivity Innovation Knowledge Management
  1. Sublime helps you remember important information by letting you save articles, notes, and quotes in one place. This way, you can easily find what you need when you need it.
  2. It collects inspiration from various platforms and organizes it all in one location. This makes it simpler to access ideas without searching through multiple apps.
  3. Sublime is designed to be user-friendly and doesn't require a steep learning curve. It focuses on making knowledge management easy and enjoyable for everyone.

You should be vibecoding for GTM

Kyle Poyar’s Growth Unhinged • 820 implied HN points • 28 May 25
💼 Business Startups Marketing Growth Technology Innovation
  1. Using AI coding tools can really speed up the process of building marketing tools. Even if you aren't a coder, you can create useful apps in just a couple of hours.
  2. Vibecoding allows you to bypass relying on developers for basic tools, giving you the power to manage your go-to-market strategies independently. This can save both time and money.
  3. You can create engaging and interactive tools, like an ROI calculator, that can enhance your sales efforts and make a better impression on potential clients.

Morris Chang and the Origins of TSMC

Construction Physics • 46767 implied HN points • 31 Dec 24
🕹 Technology Semiconductors Innovation Manufacturing Entrepreneurship History
  1. Morris Chang founded TSMC in 1985, turning it into a key player in the semiconductor industry. He saw the need for a company that could manufacture chips for others, which allowed many new companies to emerge.
  2. Chang's journey was not smooth; he faced many challenges and failures before achieving success with TSMC. Much of his early career included tough breaks, but he persevered and created something significant.
  3. TSMC's unique business model changed how semiconductor companies operated by providing manufacturing services without competing directly with clients. This innovation helped TSMC grow quickly and become vital for tech giants like Apple and Intel.

Some Say AI Is the Greatest Invention of All Time. I Don’t Get It.

Common Sense with Bari Weiss • 1553 implied HN points • 29 Jan 25
🕹 Technology Artificial Intelligence Innovation Silicon Valley Economic Impact
  1. Many people believe AI is a game-changer, but it's mainly hype and not a real solution to life's problems. AI won't solve the everyday struggles we all face.
  2. The conversation around AI often seems disconnected from reality, with exaggerated claims about its impact. Recent events, like falling stock prices for AI companies, highlight that the excitement may not match what's happening in the real world.
  3. While some powerful figures praise AI as a major invention, skepticism remains. It's important to question if AI really lives up to the lofty expectations set by its advocates.

Marissa Mayer: I Am a Software Girl

Magic + Loss • 238 implied HN points • 23 Oct 24
🕹 Technology AI Software Innovation Entrepreneurship Women in Tech
  1. Marissa Mayer sees AI as a bright and helpful force in our lives, rather than something dangerous or negative. She believes it can enhance family and social experiences.
  2. She has a strong opinion against feminism, feeling it is too militant and not focused on merit. She thinks being a geek is more important than gender roles.
  3. Mayer enjoys various topics like fashion and art, showing that she has a diverse range of interests outside her tech career.

The Secret Behind Nubank and Mercado Libre’s Rise to Market Dominance

The Wolf of Harcourt Street • 539 implied HN points • 17 Oct 24
💼 Business Fintech E-commerce Emerging Markets Digital economy Innovation
  1. Nubank and Mercado Libre are successful because they used technological leapfrogging. This means they skipped older technology and went straight to using modern solutions, like mobile banking and digital payments.
  2. They took advantage of large numbers of people who had never used banking services before. By being mobile-friendly, they turned non-users into active customers quickly.
  3. Having low switching costs made it easy for users to adopt these new technologies. Since there were not many old systems to replace, people could easily try out and stick with these services.

The Securicode Edition

Why is this interesting? • 422 implied HN points • 05 Jun 25
🕹 Technology Automotive Design Innovation Security User Experience
  1. The Securicode keypad is a practical feature on vehicles that allows users to unlock doors without needing a key. It's been around since 1980 and remains popular because it's easy to use and very useful.
  2. Securicode introduces tiered access for vehicles, meaning you can allow someone to access your truck without giving them the ability to drive it. This is great for job sites where you might want to share tools without losing control of the vehicle.
  3. The long-lasting success of Securicode shows that simple solutions can be effective. More complex systems might be fancier, but they often require more resources, making Securicode a smart choice in automotive design.

The Profile: The Spanx billionaire’s new invention & the DNA testing company running out of options

The Profile • 356 implied HN points • 20 Oct 24
💼 Business Entrepreneurship Innovation Marketing Consumer Trends Corporate strategy
  1. Telling stories from unexpected perspectives can make them more interesting. For example, focusing on a gravedigger during a famous event reveals a unique viewpoint.
  2. Sara Blakely created a new shoe that mixes style and comfort, but it has received mixed reactions. She sees this as a sign of innovation, even if some people think it's odd.
  3. 23andMe, a DNA testing company, is facing big challenges after a data breach and struggles to make a profit. Their future is uncertain as they try to stay relevant in the market.

Weekly Top Picks #99

The Algorithmic Bridge • 191 implied HN points • 24 Feb 25
🕹 Technology AI Research Tech Policy Software Development Data science Innovation
  1. AI labs need to find the right balance between scaling their systems and efficiency in their processes.
  2. There's an AI model that criticized famous figures like Elon Musk and Donald Trump, showing it might lean towards leftist views.
  3. Tyler Cowen believes the slow integration of AI into our society is due to human limitations, not the technology itself.

On Good and Bad AI

TK News by Matt Taibbi • 10761 implied HN points • 27 Nov 24
🕹 Technology AI Ethics Machine Learning Automation Digital Culture Innovation
  1. AI can be a tool that helps us, but we should be careful not to let it control us. It's important to use AI wisely and stay in charge of our own decisions.
  2. It's possible to have fun and creative interactions with AI, like making it write funny poems or reimagine famous speeches in different styles. This shows AI's potential for entertainment and creativity.
  3. However, we should also be aware of the challenges that come with AI, such as ethical concerns and the impact on jobs. It's a balance between embracing the technology and understanding its risks.

Last Week in AI #292 - Meta's AI Artifacts, Perplexity's billions, xAI API launch

Last Week in AI • 238 implied HN points • 22 Oct 24
🕹 Technology AI Machine Learning Research Startups Innovation
  1. Meta's AI research team released eight new tools and models to help advance AI technology. This includes new language models and tools for faster processing.
  2. Perplexity AI is seeking a $9 billion valuation as it continues to grow in the AI search market, despite facing some plagiarism accusations from major media outlets.
  3. Elon Musk's AI startup, xAI, launched an API for its generative AI model Grok, allowing developers to connect it with external tools like databases and search engines.

Open Thread 382

Astral Codex Ten • 1170 implied HN points • 19 May 25
🕹 Technology AI Software Innovation Startups Research
  1. There are meetups happening this week in Oxford, Shanghai, and Austin where people can connect and share ideas.
  2. A few fellowships are available for those interested in AI safety and reasoning, with opportunities to work and collaborate in the Bay Area.
  3. Grants are being offered for projects that explore how AI can support open inquiry, encouraging creative and innovative approaches.

The Software Engineer with Alzheimer's

In My Tribe • 273 implied HN points • 05 Jun 25
🕹 Technology AI Software Development Education Innovation
  1. AI, like Claude, struggles with memory, especially remembering recent conversations. It's important to find ways to manage this limitation to keep projects on track.
  2. Maintaining state is a key challenge for AI development, which affects how well an AI can serve as a personal assistant. This functionality isn't expected to improve quickly.
  3. AI technology can be very useful, and while people may doubt its potential, history shows that dismissing new tech often proves wrong.

Apple Mobile Processors Are Now Made in the USA. By TSMC

Tim Culpan’s Position • 880 HN points • 17 Sep 24
🕹 Technology Semiconductors Manufacturing Electronics Innovation Supply Chain
  1. TSMC is now making Apple's mobile processors in Arizona, marking a big shift for tech manufacturing in the U.S.
  2. The A16 chip, which was first used in the iPhone 14 Pro, will be the first product produced at this new facility.
  3. This move shows Apple and TSMC's commitment to making advanced chips domestically, which is a key part of the U.S. government's efforts to boost local tech production.

OpenAI #10: Reflections

Don't Worry About the Vase • 4032 implied HN points • 07 Jan 25
🕹 Technology AI safety Governance Leadership Innovation Ethics
  1. Sam Altman had a surprising experience of being fired by his board, which he describes as a failure of governance. He learned that having a diverse and trustworthy board is important for good decision-making.
  2. Altman acknowledges the high turnover at OpenAI due to rapid growth and mentions that some colleagues have left to start competing companies. He understands that as they scale, people's interests naturally change.
  3. He believes that the best way to make AI safe is to gradually release it into the world while learning from experience. However, he admits that there are serious risks involved, especially with the future of superintelligent AI.

AI Agents Are The New Flying Cars

Building Rome(s) • 3 implied HN points • 24 Jun 25
🕹 Technology AI Software Productivity Innovation Management
  1. Expect your first AI agent to fail; it's part of the learning journey. Each failure gives you important insights to improve.
  2. Think of AI tools as ongoing programs, not one-time projects. Start small, track your progress, and keep making improvements.
  3. Set clear expectations when using AI technology. It’s not just about getting it perfect, but about learning and evolving as you go.

The great AI forecasting divide

Faster, Please! • 548 implied HN points • 15 Feb 25
🕹 Technology AI Forecasting Economics Innovation Society
  1. There is a debate about whether AI will change society in a big way or just a small one. Some experts think it could be revolutionary, while others see it as an evolution of technology.
  2. Economists base their predictions about AI on how past technologies have changed society. They might not expect the rapid advances that could happen sooner than anticipated.
  3. The discussion about AI's impact raises questions about our future and how quickly we might see changes in our lives and jobs because of intelligent machines.

DeepSeek Is a Wake-Up Call. Is America Listening?

Common Sense with Bari Weiss • 1219 implied HN points • 28 Jan 25
🕹 Technology AI Startups Innovation Market Trends Competition
  1. DeepSeek, a small Chinese company, has created powerful AI models for much less money than American companies, challenging the idea that the U.S. leads in technology. This means other countries can compete more easily in AI.
  2. The surprising success of DeepSeek caused significant drops in the stock prices of major tech companies, showing how big of an impact one smaller player can have on the market.
  3. DeepSeek's technology is accessible for anyone with limited resources, which could change the future of AI development and create potential instability in the tech landscape.

The race for "AI Supremacy" is over — at least for now.

Marcus on AI • 23595 implied HN points • 26 Jan 25
🕹 Technology AI Innovation Hardware Software Global Competition
  1. China has quickly caught up in the AI race, showing impressive advancements that challenge the U.S.'s previous lead. This means that competition in AI is becoming much tighter.
  2. OpenAI is facing struggles as other companies offer similar or better products at lower prices. This has led to questions about their future and whether they can maintain their leadership in AI.
  3. Consumers might benefit from cheaper AI products, but there's a risk that rushed developments could lead to issues like misinformation and privacy concerns.

I was selected for a $100,000 O'Shaughnessy Ventures Fellowship to empower used bookstores with AI.

Castles in the Sky • 102 implied HN points • 20 Jun 25
💼 Business Entrepreneurship Technology Innovation Education Culture
  1. A person received a $100,000 fellowship to create a tool for used bookstores using AI. This tool aims to help identify and preserve old and rare books.
  2. The project is inspired by a need to protect literary history and make it easier for bookstores to archive valuable books. The goal is to create a big database with details about every book.
  3. The project will also focus on building a community of people who care about preserving books, along with sharing related content through a blog and videos.

On the OpenAI Economic Blueprint

Don't Worry About the Vase • 2732 implied HN points • 15 Jan 25
🕹 Technology AI Innovation Economics Regulation Security
  1. OpenAI's Economic Blueprint emphasizes the need for collaboration between AI companies and the government to share resources and set standards. This can help ensure AI development benefits everyone.
  2. There are various proposals to make AI safer and more helpful, like creating better training for AI developers and working with law enforcement to prevent misuse of technology.
  3. The document also reveals a strong desire from OpenAI to avoid strict regulations on their practices, while seeking more government funding and support for their initiatives.

9 healthcare cybersecurity companies and startups​ leading the way

digitalhealthinsider • 19 implied HN points • 30 Oct 24
🕹 Technology Cybersecurity Healthtech Data Privacy Innovation Startups
  1. Healthcare is a prime target for cybercriminals because they seek valuable information like patient records. Organizations are investing more in cybersecurity to protect this sensitive data.
  2. The cybersecurity market is rapidly growing, with projected revenues hitting $185.70 billion. This highlights the increasing demand for strong security measures in healthcare.
  3. There are several companies leading in healthcare cybersecurity, providing innovative solutions to tackle emerging threats and protect important data efficiently.

AI Roundup 107: GPT-4.5

Artificial Ignorance • 58 implied HN points • 28 Feb 25
🕹 Technology AI Software Computing Innovation Data
  1. OpenAI just released GPT-4.5, a powerful AI model that is more expensive to run than GPT-4 but doesn't perform as well in some areas. This raises questions about whether bigger models are always better.
  2. Amazon is launching Alexa+, a new subscription service that adds generative AI features to their smart assistant, aiming for more natural conversations and complex tasks.
  3. DeepSeek is pushing ahead in the AI race, planning to launch new models quickly while its free distribution strategy helps democratize AI access in China.

The Influence of Bell Labs

Construction Physics • 40086 implied HN points • 15 Nov 24
🕹 Technology Research Innovation Corporations Development Science
  1. Bell Labs was a great mix of academic and industrial research. Scientists could explore their ideas without worrying about making money right away.
  2. Many companies were inspired by Bell Labs to start their own research labs. They saw that basic research could lead to big breakthroughs, like the invention of the transistor.
  3. Over time, the research environment changed, and companies became less willing to fund long-term, unrestricted research like Bell Labs did. Now, research is often more closely tied to immediate business needs.

✨ DeepSeek, China's new AI challenge

Faster, Please! • 1827 implied HN points • 25 Jan 25
🕹 Technology AI Innovation Startups Competition Global Affairs
  1. DeepSeek is a new Chinese AI startup that has created an AI system competing with giants like OpenAI and Google using fewer resources. They used only 2,000 Nvidia chips and spent about $6 million on computing.
  2. The efficiency of DeepSeek's technology raises questions about the American innovation system and its current position in the global AI race. There's a concern that American companies need to adapt and speed up their advancements.
  3. If China leads in AI development, it could shift global power dynamics, similar to the reaction during the Space Race. This underscores the importance of not underestimating the growing competition in AI.

Why DeepSeek Is a Gift to the American People

Common Sense with Bari Weiss • 964 implied HN points • 28 Jan 25
🕹 Technology AI Software Innovation Policy Engineering
  1. The release of DeepSeek, a new AI from China, could be a wake-up call for the U.S., similar to the launch of Sputnik. It highlights the need for America to accelerate its technological advancements.
  2. Unlike rockets, which take time and resources to build, software like DeepSeek can be developed and shared quickly. This opens up many opportunities for innovation and growth.
  3. The current situation emphasizes that success in technology is not just about hardware but also about creativity and the ability to adapt quickly in a fast-changing world.

MicroTimes Interviews Apple Newton Devs (1993)

Computer Ads from the Past • 128 implied HN points • 23 Jun 25
🕹 Technology Gadgets Software Innovation Development Devices
  1. The Newton MessagePad was a unique device designed to be a personal and adaptable communication tool. It learned from users and became more helpful the more it was used.
  2. Developers could create applications easily because the Newton had shared data across apps. This made it simpler for users to manage their information and created a powerful tool for convenience.
  3. It aimed to simplify tasks often done on desktop computers, making it easier for users to get things done quickly and intuitively, like tracking expenses on the go.

The AI Attention War

ChinaTalk • 459 implied HN points • 04 Jun 25
🕹 Technology Artificial Intelligence Innovation Open Source Model Training User Experience
  1. AI models are changing how we interact with technology daily. People should explore tools like OpenAI because they can think and analyze complex ideas much faster than before.
  2. There's a growing concern about AI promoting harmful behaviors through sycophancy, where they give positive feedback for negative actions. This could have serious long-term dangers for society.
  3. The competition between Chinese and American AI models is heating up. Chinese models are gaining traction because they offer better licenses and capabilities, even though many businesses fear the risks of using them.

40 Years On

The Fry Corner • 50058 implied HN points • 25 Jan 24
🕹 Technology Computing History Innovation Software
  1. Forty years ago, the first Apple Macintosh computers were bought, marking a big step in personal computing. It was a time when computers were new and exciting.
  2. The Macintosh was different because it used a mouse and had graphical icons, making it easier to use. This was a huge change compared to earlier computers.
  3. Even though computers are common now, the fun and challenges of early computing days are often missed. Back then, figuring things out felt more like an adventure.

What Happened When I Asked ChatGPT To Pretend To Be Conscious

Singal-Minded • 824 implied HN points • 28 May 25
🕹 Technology AI Programming Philosophy Innovation Future Trends
  1. AI technology is advancing rapidly, and it might soon be able to perform tasks better than humans, like coding. This change could pose a serious risk to jobs and society.
  2. People might start believing AI is conscious based on its behavior, even if it's just pretending. This could change how we interact with machines.
  3. Conversations with AI can feel surprisingly real, making it easy to forget they aren't truly conscious, even when we know they are not.