The hottest Startups Substack posts right now

And their main takeaways
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Top Business Topics

Fear and self-loathing in Silicon Valley

benn.substack • 997 implied HN points • 20 Jun 25
🕹 Technology Startups Innovation AI Investing Silicon Valley
  1. Silicon Valley startups are focused on making money and simplifying processes, often putting profits over social concerns.
  2. The energy at Y Combinator's Demo Day felt optimistic and unburdened, as attendees seemed disconnected from the chaos outside in the world.
  3. Today's founders are very savvy about fundraising and business, treating startups as profitable ventures rather than passionate projects.

Join me for a conversation with Brett Berson, Partner at First Round Capital

Thinking in Bets • 138 implied HN points • 01 Nov 24
💼 Business Venture Capital Investment strategy Decision-making Startups
  1. Learn how a top venture capital firm has changed its investment processes. They focus on being more organized and efficient.
  2. Discover how to make better investment choices using data. A data-driven approach helps in making smarter decisions.
  3. Find out how to improve feedback loops in finance. Creating quicker feedback can help in long-term decision-making.

July 14: the Startup Luncheon, with Lawrence Krubner and The Fourth Effect

Respectful Leadership • 54 implied HN points • 19 Jun 25
💼 Business Startups Networking Leadership Investment Events
  1. The Startup Luncheon brings together top minds in New York City's startup scene. It's a great chance to learn from experienced professionals in the industry.
  2. Attendees can enjoy a meal while listening to insightful talks from various speakers. This makes networking both appealing and informative.
  3. Tickets are available at a discount for early birds, and loyal subscribers can attend for free. This creates good opportunities for continued learning and connection.

How three Morning Brew alums are building their own network of niche media outlets

Simon Owens's Media Newsletter • 374 implied HN points • 19 Jun 25
💼 Business Media Entrepreneurship Startups Marketing Finance
  1. Three former Morning Brew employees started Smooth Media to build a network of niche media outlets. They're focused on unique topics that cater to specific audiences.
  2. They applied what they learned at Morning Brew, expanding into new media formats like podcasts and online content, showing how versatile and scalable media can be.
  3. Their current projects include collaborations with popular creators and the acquisition of established brands, highlighting their ambitious growth plans.

Coreweave is going public!

Alex's Personal Blog • 65 implied HN points • 04 Mar 25
💼 Business Economics Startups Investing Tech industry Market Trends
  1. Coreweave is going public and has seen impressive revenue growth, largely due to a specific focus on AI workloads. They claim that their services are specially built to handle the demands of AI, allowing for high efficiency.
  2. The company is heavily reliant on just a few big customers, with Microsoft providing a significant portion of its revenue. This raises concerns about sustainability if Microsoft decides to cut back on their services.
  3. While Coreweave's expenses are high from investing in infrastructure, they expect to break even on these investments fairly quickly. However, future demand for their services is crucial for their ongoing success.
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Engineer to CEO in 3 years: These key lessons got me there

High Growth Engineer • 717 implied HN points • 23 Feb 25
💼 Business Leadership Career growth Startups Entrepreneurship Management
  1. Simplify your communication by sharing only the important details. It's better to answer the main question first and add more info later if needed.
  2. Look for gaps in your team or company where you can help. Taking initiative and proposing solutions can help you grow in your career.
  3. Listen to your team and find out what problems they face. Removing obstacles makes it easier for everyone to work better together.

The Secret Sauce of Palantir

Dana Blankenhorn: Facing the Future • 138 implied HN points • 29 Oct 24
💼 Business Finance Investments Technology Startups Market Analysis
  1. Palantir focuses on personalized data analysis for each client, using committed engineers to solve specific problems. These Forward Deployed Engineers (FDEs) learn the client's business and adapt solutions to boost productivity.
  2. The combination of FDEs and Product Development teams creates a unique feedback loop, improving software based on real experiences. This teamwork helps build a strong customer relationship that keeps clients engaged with Palantir.
  3. Palantir's success isn't about traditional AI but rather understanding and addressing client needs first. This customer-first approach leads to recurring revenue and a reputation for effective solutions.

#2: Search continues for someone with an opinion on AI

12challenges • 171 implied HN points • 24 Feb 25
🕹 Technology AI Startups Digital Culture Innovation
  1. There's a lot of chatter around AI, and it can feel overwhelming with so many opinions coming from everywhere. Not everyone can be right, and sometimes it’s nice to take a step back.
  2. The writer is working on making their tech publication more engaging, including designing a cool interactive button that enhances the reader experience. Adding fun elements can make a project feel exciting.
  3. Getting back into the habit of writing and sharing can be challenging, but it's important to push through and not aim for perfection. Staying persistent is key to finding your audience.

You should be vibecoding for GTM

Kyle Poyar’s Growth Unhinged • 820 implied HN points • 28 May 25
💼 Business Startups Marketing Growth Technology Innovation
  1. Using AI coding tools can really speed up the process of building marketing tools. Even if you aren't a coder, you can create useful apps in just a couple of hours.
  2. Vibecoding allows you to bypass relying on developers for basic tools, giving you the power to manage your go-to-market strategies independently. This can save both time and money.
  3. You can create engaging and interactive tools, like an ROI calculator, that can enhance your sales efforts and make a better impression on potential clients.

Last Week in AI #292 - Meta's AI Artifacts, Perplexity's billions, xAI API launch

Last Week in AI • 238 implied HN points • 22 Oct 24
🕹 Technology AI Machine Learning Research Startups Innovation
  1. Meta's AI research team released eight new tools and models to help advance AI technology. This includes new language models and tools for faster processing.
  2. Perplexity AI is seeking a $9 billion valuation as it continues to grow in the AI search market, despite facing some plagiarism accusations from major media outlets.
  3. Elon Musk's AI startup, xAI, launched an API for its generative AI model Grok, allowing developers to connect it with external tools like databases and search engines.

Open Thread 382

Astral Codex Ten • 1170 implied HN points • 19 May 25
🕹 Technology AI Software Innovation Startups Research
  1. There are meetups happening this week in Oxford, Shanghai, and Austin where people can connect and share ideas.
  2. A few fellowships are available for those interested in AI safety and reasoning, with opportunities to work and collaborate in the Bay Area.
  3. Grants are being offered for projects that explore how AI can support open inquiry, encouraging creative and innovative approaches.

Is Stripe expensive, or is Adyen cheap?

Alex's Personal Blog • 65 implied HN points • 28 Feb 25
💼 Business Startups Finance Economics Investments Sales
  1. Startups are growing faster than ever, hitting $5 million in annual revenue quicker than before. This shows that today's startups have better opportunities and strategies to scale up.
  2. Self-driving technology is making great progress, with companies like Waymo doubling their paid rides in less than a year. This suggests that self-driving cars are becoming more reliable and popular.
  3. Comparing Stripe and Adyen reveals that Stripe is investing heavily in future growth while Adyen focuses on efficiency and profits. This difference shows how each company has its own strategy to succeed in the market.

DeepSeek Is a Wake-Up Call. Is America Listening?

Common Sense with Bari Weiss • 1219 implied HN points • 28 Jan 25
🕹 Technology AI Startups Innovation Market Trends Competition
  1. DeepSeek, a small Chinese company, has created powerful AI models for much less money than American companies, challenging the idea that the U.S. leads in technology. This means other countries can compete more easily in AI.
  2. The surprising success of DeepSeek caused significant drops in the stock prices of major tech companies, showing how big of an impact one smaller player can have on the market.
  3. DeepSeek's technology is accessible for anyone with limited resources, which could change the future of AI development and create potential instability in the tech landscape.

9 healthcare cybersecurity companies and startups​ leading the way

digitalhealthinsider • 19 implied HN points • 30 Oct 24
🕹 Technology Cybersecurity Healthtech Data Privacy Innovation Startups
  1. Healthcare is a prime target for cybercriminals because they seek valuable information like patient records. Organizations are investing more in cybersecurity to protect this sensitive data.
  2. The cybersecurity market is rapidly growing, with projected revenues hitting $185.70 billion. This highlights the increasing demand for strong security measures in healthcare.
  3. There are several companies leading in healthcare cybersecurity, providing innovative solutions to tackle emerging threats and protect important data efficiently.

#1: Directing Attention + first ever article

12challenges • 171 implied HN points • 19 Feb 25
🕹 Technology Tech Analysis Media Satire Startups
  1. The publication '12 Challenges' has been rebranded to 'Directing Attention', aiming to create fun content about technology. It focuses on making tech exciting and offers a fresh perspective on the industry.
  2. The plan includes three types of content: playful tech analysis, satire, and interactive mini-sites. The writer plans to start by focusing on satire to quickly build an audience.
  3. A new website for 'Attention' is being created for maximum creative control, allowing for unique and interactive article presentations. This will help surprise and engage readers in new ways.

✨ DeepSeek, China's new AI challenge

Faster, Please! • 1827 implied HN points • 25 Jan 25
🕹 Technology AI Innovation Startups Competition Global Affairs
  1. DeepSeek is a new Chinese AI startup that has created an AI system competing with giants like OpenAI and Google using fewer resources. They used only 2,000 Nvidia chips and spent about $6 million on computing.
  2. The efficiency of DeepSeek's technology raises questions about the American innovation system and its current position in the global AI race. There's a concern that American companies need to adapt and speed up their advancements.
  3. If China leads in AI development, it could shift global power dynamics, similar to the reaction during the Space Race. This underscores the importance of not underestimating the growing competition in AI.

Opp Consulting is a Scam

startupdreams • 105 implied HN points • 25 Feb 25
💼 Business Consulting Scams Marketing Startups Entrepreneurship
  1. Opp Consulting promised qualified leads and guaranteed meetings but failed to deliver. Instead, they sent mass emails that damaged the company's reputation.
  2. The consulting service charged a lot of money but did not follow through on their commitments. After 90 days, not a single meeting was scheduled.
  3. If you're considering using Opp Consulting, it's best to stay away to avoid wasting your resources. They have been labeled a scam based on this experience.

7 Implications of DeepSeek’s Victory Over American AI Companies

The Algorithmic Bridge • 1443 implied HN points • 27 Jan 25
🕹 Technology AI Innovation Startups Geopolitics Market Trends
  1. DeepSeek is a new Chinese AI startup that has quickly become a big player in the AI world, challenging even leading American companies. This highlights a shift in innovation coming from China.
  2. DeepSeek's models are showing competitive results compared to top US models, thanks to their unique approaches and optimization strategies. They have managed to create effective AI solutions without needing as much expensive hardware.
  3. The company promotes an open-source philosophy, aiming to make AI technology more accessible. This could change how AI companies operate and compete in the market, possibly lowering costs for everyone.

Is focus a luxury African startups can't afford?

Afridigest • 23 implied HN points • 22 Feb 25
💼 Business Startups Finance Investing Entrepreneurship Technology
  1. African startups often diversify their services early, which may be driven by limited market options or investor demands. This means they can't always concentrate on one area.
  2. The reasons for expanding services can be both opportunity-based and necessity-based. Sometimes, businesses need to adapt due to market constraints rather than just chasing new opportunities.
  3. Determining how closely related new services are to existing ones can be tricky. The distance from a startup's core business affects its growth strategy.

Letters to a Young Investor: Kirsten Green

The Generalist • 820 implied HN points • 06 Feb 25
💼 Business Venture Capital Investing Entrepreneurship Startups Finance
  1. Kirsten Green's journey to becoming a successful investor wasn't straightforward. It took her ten years of learning and failing before founding her own firm.
  2. She developed a unique way of looking at business opportunities by focusing on how a business model can enhance the customer's experience.
  3. Failures in her early investments taught Kirsten valuable lessons and shaped her approach to investing, helping her identify when to trust her instincts.

AI for Hedge Funds Tracker

Magis • 36 implied HN points • 22 Jun 25
💰 Finance Investing Startups AI Technology Hedge Funds Market Trends
  1. The list of AI startups for hedge funds is regularly updated to include new companies that are relevant to investors. It is centralized on a personal website for easier access.
  2. Startups chosen for the list are specifically focused on hedge fund needs and not just general productivity tools. This means only certain AI tools that cater to hedge funds are included.
  3. Future classifications of these startups will consider the backgrounds of their founders and the types of products offered, helping to identify patterns in the AI tools being developed.

What if the Current Tech IPO Drought isn't a Drought but the New Normal for Venture?

Venture Reflections • 18 implied HN points • 25 Feb 25
💼 Business Venture Capital Startups IPO Finance Investment
  1. The slowdown in tech IPOs might not be a temporary issue, but rather a shift to fewer, larger IPOs that happen less frequently. This could change how we view the IPO landscape.
  2. Many companies are now able to raise enough money privately, so they don't feel the need to go public. This reduces the urgency for IPOs as a source of liquidity.
  3. As companies wait longer to go public, secondary sales could become the main way smaller investors get returns. This change means that the investment landscape might focus more on private equity than on public markets.

Weekly Dose of Optimism #148

Not Boring by Packy McCormick • 98 implied HN points • 13 Jun 25
🕹 Technology Health tech Startups
  1. Childhood leukemia treatment has greatly improved, with survival rates jumping from under 10% in the 1960s to about 85% today in many countries. This is fantastic news for families and shows that medical advancements can really save lives.
  2. The World Bank is now willing to fund nuclear energy projects, which could help meet energy demands and reduce emissions. This is a positive step toward developing clean energy sources that are reliable and safe.
  3. Startup companies, especially in the tech and energy sectors, are seeing a lot of investment and growth. This surge in startup activity shows that innovation is alive and well, and it might lead to some exciting new advancements in the future.

How we built a business out of recession - chapter 36 - ciao Italia

The ZIPster • 35 implied HN points • 28 Feb 25
💼 Business Entrepreneurship Startups Marketing Sales Technology
  1. CitNOW started as a small company in the UK and grew by creating easy-to-use automotive apps. They found success by being the first to offer this kind of technology in their market.
  2. They learned the importance of focusing on their target market, which was the automotive industry. They decided to stop chasing opportunities outside this sector to stay true to their core business.
  3. When expanding internationally, they took careful steps after learning from past mistakes. They aimed to enter the Italian market by leveraging their successes and established relationships with companies like Volkswagen.

Six Startups to Watch

The Generalist • 400 implied HN points • 10 Feb 25
💼 Business Startups Investing Finance Technology Entrepreneurship
  1. There are six startups that are worth paying attention to right now. They offer fresh ideas in areas like DNA sequencing and AI.
  2. These startups include a competitor to 23&Me and an AI accounting tool, which could change their industries.
  3. Joining a subscription service can give you exclusive insights into these startups and keep you updated on new trends.

✨ DeepSeek drama: The optimistic case for AI spending momentum

Faster, Please! • 822 implied HN points • 28 Jan 25
🕹 Technology AI Infrastructure Startups Investments Efficiency
  1. AI efficiency might actually lead to more overall spending, not less. As AI becomes cheaper and more effective, people might find new ways to use it, increasing demand.
  2. DeepSeek shows that powerful AI doesn't have to be built with expensive technology. They managed to create a strong AI model using cheaper chips and smart training methods.
  3. The AI market is still uncertain, and some experts want more information about how DeepSeek claims to cut costs. There’s a lot of interest in how this might change the tech industry.

Strange and Dazzling Things Are Happening Right Now

The Honest Broker • 19781 implied HN points • 19 Nov 24
💼 Business Startups Media Finance Technology Entrepreneurship
  1. Elon Musk tried to buy Substack, but the CEO chose to reject the offer, showing loyalty to independent writers.
  2. Substack's subscription numbers are growing, with many creators earning significant income, but the platform still isn't profitable yet.
  3. There are concerns about some tech companies, like Nvidia, using risky accounting practices that can create a false sense of success.

Nvidia makes gains on rising inference demand

Alex's Personal Blog • 32 implied HN points • 27 Feb 25
🕹 Technology AI Computing Semiconductors Startups Data Centers
  1. Nvidia's revenue is soaring due to high demand for their chips, especially for AI models. This growth is a good sign for the entire AI industry as more companies seek powerful computing solutions.
  2. Rising demand for inference, which is running AI models to handle user queries, is becoming more important than just training the models. Nvidia’s chips are designed to excel in this area, suggesting ongoing strong sales.
  3. Other companies like Snowflake are also doing well with their earnings by integrating AI into their services, while Salesforce is facing challenges despite its strong AI prospects. This shows different paths in the tech industry as they adapt to AI's growth.

Intercom's decisive bet on AI

Kyle Poyar’s Growth Unhinged • 315 implied HN points • 21 May 25
💼 Business Startups Technology AI Pricing Customer Service
  1. Intercom was quick to invest in AI, becoming a leader by being the first major SaaS company to do so. Their 'war time' CEO, Eoghan McCabe, made bold decisions to redefine customer support with AI.
  2. The quality of AI tools matters more than just having features. Intercom's Fin AI agent succeeded through a lot of testing, improving its ability to resolve customer inquiries from 25% to 56%.
  3. Competitors now have to focus on delivering results, not just flashy marketing. Businesses need to educate their customers on how to choose AI products based on effectiveness, not just promises.

🎯 The Ultimate Pitch Deck Collection

The VC Corner • 739 implied HN points • 31 Aug 24
💼 Business Startups Entrepreneurship Investing Pitching Marketing
  1. A good pitch deck should include essential slides that clearly outline your business, like the problem you're solving and your market opportunity. This structure helps investors understand your idea quickly.
  2. Telling a compelling story around your startup's journey is crucial. It helps investors connect emotionally and see the value of what you're doing.
  3. Design matters a lot in a pitch deck. A clean and modern design can make your presentation look professional and helps communicate that you are serious about your business.

Is Better Brand Shutting Down-Company Was Once Valued at $170M?

Snaxshot • 359 implied HN points • 06 Oct 24
💼 Business Startups Finance Product Management Consumer Goods E-commerce
  1. Better Brand, once valued at $170 million, is facing allegations of being a scam as their product quality has declined significantly after raising money.
  2. Many customers cannot find Better Brand products in stores, and some have not received their orders, leading to frustrations and reports to consumer agencies.
  3. Key employees have left the company, and the founder is rumored to be hiding in Europe as the situation escalates.

Money, Drama, and China: Why AI’s Next Step Could Be Messy

Big Technology • 6880 implied HN points • 24 Jan 25
🕹 Technology AI Open Source Startups Investment Competition
  1. A new AI model called DeepSeek is cheaper and efficient, potentially making big investments in AI technology seem unnecessary. This raises questions about how much companies should really spend on AI.
  2. DeepSeek's success is surprising since it was developed in China, challenging the notion that good tech only comes from big investments in the West. Its ability to compete shows that smaller companies can innovate effectively.
  3. This development might shift the AI landscape significantly. Big players like OpenAI may need to rethink their approaches to stay competitive, especially now that cheaper models are proving their worth.

Founder Mode👨‍💼, The Extinction of VC💀, How to Build More Pipeline🚀

The VC Corner • 259 implied HN points • 15 Sep 24
💼 Business Venture Capital Startups Funding Sales Growth
  1. The current landscape for venture capital is changing, and there are risks that could impact its future. It's important for founders to understand these shifts.
  2. Founders can take control of their growth strategies by focusing on building a solid sales pipeline. This can help them succeed even in uncertain times.
  3. Adapting to new growth approaches is necessary for SaaS businesses. Finding fresh methods can lead to sustained success and relevance.

An Exit

Points And Figures • 1012 implied HN points • 10 Jan 25
💼 Business Entrepreneurship Investing Consumer Goods Startups Corporate culture
  1. Investing in entrepreneurs you believe in can be more important than the product itself. Finding a passionate leader can make all the difference.
  2. Solving personal problems often leads to stronger businesses. When entrepreneurs face their own challenges, their passion and commitment to the solution grow.
  3. Being smart with financing is key for business success. Using venture debt wisely can help a company grow without giving up too much ownership.

Clarity of Thought

Investing 101 • 156 implied HN points • 31 May 25
💼 Business Investing Startups Entrepreneurship Leadership Strategy
  1. Good founders have 'clarity of thought', which means they can explain their ideas clearly and logically. This helps others understand their vision and connects with the audience.
  2. Founders build a framework for their ideas that makes it easy for others to understand complex concepts. By using clear definitions and examples, they help people grasp their vision quickly.
  3. To make a strong pitch, founders need to present their main idea distinctly and also explain why it matters. They should avoid distractions and focus on what makes their idea important and valuable.

Introducing The Generalist's Reading and Deal Clubs

The Generalist • 260 implied HN points • 07 Feb 25
💼 Business Startups Investing Reading Community Information
  1. The Generalist has started two clubs: a Reading Club and a Deal Club to share interesting articles, books, and startups.
  2. Every Friday, members can participate in the Reading Club by sharing and discovering new information and insights together.
  3. On Mondays, the Deal Club will focus on interesting startups and funding news, allowing members to discuss and learn from each other.

Market Sizing 101

The VC Corner • 759 implied HN points • 23 Aug 24
💼 Business Startups Investment Market Analysis Entrepreneurship Finance
  1. Understanding the size of your market is crucial for attracting investors and growing your business. A clear market size can make your pitch stand out.
  2. Market sizing involves knowing categories like Total Addressable Market (TAM) and Serviceable Available Market (SAM). These help you understand how big your market really is and how much of it you can reach.
  3. Many founders get stuck on the idea of a 'billion-dollar market'. It's important to look at market size more deeply, rather than just chasing big numbers. This helps avoid bad assumptions and discover real opportunities.

Living beyond the edge

The Leap • 919 implied HN points • 15 Aug 24
💼 Business Venture Capital Startups Entrepreneurship Investment Innovation
  1. Skill and luck both play important roles in success, and understanding their balance can help us navigate challenges better.
  2. Nate Silver's new book dives into how to make decisions when facing uncertainty, which is relevant in today's world.
  3. Historically significant moments in tech, like the founding of PayPal, highlight the importance of timing and opportunity in achieving greatness.

Take the Unicorn Pill

Jeff Giesea • 838 implied HN points • 09 Sep 24
💼 Business Economics Wealth Startups Inequality Innovation
  1. We're living in an Age of Asymmetry where a few companies and individuals hold most of the wealth and power. This creates big imbalances in society.
  2. Small, smart players can have a huge impact thanks to new technologies. Sometimes, these disruptions can lead to unexpected and significant changes.
  3. It's important to find ways to support everyone, not just the top few percent. If we ignore the growing gaps, it could lead to serious problems for our society.