The hottest Genetics Substack posts right now

And their main takeaways
Category
Top Health & Wellness Topics
sebjenseb β€’ 196 implied HN points β€’ 10 Feb 24
  1. Assortative mating occurs between races, with individuals who date outside their race being more similar to each other in terms of intelligence, height, and risk-taking behaviors.
  2. Current literature suggests that interracial relationships may have a higher likelihood of ending or experiencing domestic violence issues, and mixed-race children might be more prone to mental/behavioral problems, possibly due to self-selection rather than social factors.
  3. Attractiveness was a weak predictor of interracial dating across all races, indicating that mate value or race exchanges based on mate value were not significant factors in interracial dating.
Razib Khan's Unsupervised Learning β€’ 983 implied HN points β€’ 23 Sep 23
  1. Indo-European languages have spread widely across the globe through historical events and cultural exchanges.
  2. Genomic technologies have revolutionized our understanding of the rise and spread of Indo-Europeans.
  3. Debates around Indo-European origins have evolved, integrating fields like genetics, archaeology, and linguistics.
Asimov Press β€’ 251 implied HN points β€’ 24 Jan 24
  1. Applying the Five Whys technique helps to identify the root cause of complex problems effectively.
  2. Investigating and understanding the root cause of diseases like diabetes requires in-depth research and methodology.
  3. In science, it's crucial to focus on finding root causes in biology and medicine to advance our understanding of complex diseases.
Wyclif's Dust β€’ 1001 implied HN points β€’ 17 Sep 23
  1. Polygenic scores predicting education levels also predict fertility in opposite directions.
  2. Economic theory explains the relationship between income, education, and number of children.
  3. US data on natural selection shows differences compared to the UK, possibly influenced by factors like welfare support and class distinctions.
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Insight Axis β€’ 612 implied HN points β€’ 12 Nov 23
  1. Giraffes have long necks to better reach food on tall trees, increasing their chances of survival and passing on their genes.
  2. In the true story of giraffes' evolution, genes are the main characters that hold knowledge for survival in their environment.
  3. Humans, unlike giraffes, can create their own knowledge using their minds, allowing them to survive in diverse environments and even outer space.
Parrhesia β€’ 456 implied HN points β€’ 09 Dec 23
  1. Beliefs and ideologies are influenced by genetics, affecting the future through who has children.
  2. Changes in fertility patterns due to ideologies can impact the prevalence of certain traits in future generations.
  3. Advocating for genetic enhancement technologies can shape future generations' traits even if you choose not to have children.
Asimov Press β€’ 96 implied HN points β€’ 07 Mar 24
  1. The Vector Zoo showcases humanity's battle to eradicate zoonotic and vector-borne diseases, emphasizing the challenges faced in diseases like malaria due to shifting parasites and vectors.
  2. The Last Mile Labyrinth in the Vector Zoo symbolizes the choice between collaborative efforts towards disease eradication or reverting to isolated living, highlighting the complexities and costs involved in disease elimination.
  3. The Temple of Political Will in the Vector Zoo underscores the critical role of social and political commitment in disease eradication, demonstrating the impact of funding and investments in public health initiatives.
Grey Goose Chronicles β€’ 1257 implied HN points β€’ 23 Jul 23
  1. Evidence suggests that the earliest human ancestors in Europe evolved in Europe before eventually moving to Africa.
  2. The arrival of different human species in Europe can be traced through archaeological findings and genetic studies.
  3. Neanderthals existed in Europe for a long time, and the arrival of modern humans led to significant changes and interactions.
Nepetalactone Newsletter β€’ 1749 implied HN points β€’ 12 Apr 23
  1. Sequencing of Pfizer vaccines showed dual copies of a 72-bp SV40 Promoter
  2. The assembly struggled to handle a 72-bp tandem repeat with 105bp insert sizes
  3. The data corrected the assumption of multiple vectors in Pfizer vaccines, indicating a single vector with an additional 72bp repeat
Razib Khan's Unsupervised Learning β€’ 429 implied HN points β€’ 27 Nov 23
  1. In 2003, research revealed that a significant number of men worldwide are direct descendants of Genghis Khan, showing how a single lineage can rapidly expand across generations.
  2. The genetic legacy of powerful individuals like Genghis Khan can have a lasting impact on populations through prolific breeding and intermarriages.
  3. Studies on Y-chromosomal lineages, like those associated with Genghis Khan, indicate social selection through behaviors like conquest and harem-building driving the sudden expansion of specific genetic lineages.
Trevor Klee’s Newsletter β€’ 522 implied HN points β€’ 31 Oct 23
  1. Insulin is not exclusive to humans but is a common hormone across various species.
  2. Cavefish have unique adaptations for survival in harsh conditions like darkness and limited food sources.
  3. The evolution of insulin resistance and obesity in cavefish provides insights into how different species handle metabolism.
Wyclif's Dust β€’ 1501 implied HN points β€’ 14 Apr 23
  1. The MAF/effect size slope gets steeper below MAF of 0.1, but correction becomes less trustworthy.
  2. There is a slope in the EA/fertility relationship above MAF of 0.1, so it's not constant everywhere.
  3. The relationship between EA/fertility is smaller for rare alleles, but the impact of very rare mutations remains uncertain.
Razib Khan's Unsupervised Learning β€’ 789 implied HN points β€’ 27 May 23
  1. Human evolutionary science has shifted from complex models to explain the intricacies of our origins.
  2. Advances in genetics, DNA analysis, and paleoanthropology have revolutionized our understanding of human evolution.
  3. The concept of a single, simple origin of modern humans from Africa has evolved into a more complex and rich tapestry of multiple populations and dynamics.
Risk Musings β€’ 573 implied HN points β€’ 22 Jul 23
  1. Nature builds from the bottom up through evolution and mutations, unlike top-down engineering in human systems.
  2. Biomimicry offers inspiration across various fields by learning from nature's efficient and resilient systems.
  3. Bottom-up building, like in the human brain, involves countless interactions that lead to emergent solutions, unlike enforced top-down strategies.
Vectors of Mind β€’ 825 implied HN points β€’ 10 May 23
  1. Women may have evolved recursion before men, based on prehistoric myths and societal structures.
  2. The downsides and challenges of recursion may have led to unique pathways for human development.
  3. Gendered differences in genetic, cognitive, and cultural factors could have influenced the evolution of self-awareness and recursion in humans.
Logging the World β€’ 418 implied HN points β€’ 23 Aug 23
  1. New COVID variant BA.2.86 has mutations that suggest fast growth, but estimating its growth rate is tricky.
  2. Statisticians use models and likelihood functions to estimate parameters like growth rates, but uncertainty exists in the estimates.
  3. The work of statistician C.R. Rao, like the Fisher information, shows fundamental limits to parameter estimation and the role of geometry in statistics.
Grey Goose Chronicles β€’ 727 implied HN points β€’ 09 May 23
  1. Native Americans were using horses over a hundred years before previously thought, shaping a new view of early Plains societies.
  2. Genetic analysis confirms migration and intermixing with Persians on Africa's Swahili coast, challenging long-held theories.
  3. Bronze Age Menorca revealed evidence of the use of powerful drugs, shedding light on ancient rituals and practices.
Parrhesia β€’ 685 implied HN points β€’ 10 Apr 23
  1. In vitro gametogenesis (IVG) could revolutionize reproduction by providing more eggs for embryo creation.
  2. Increased availability of eggs through IVG can lead to significant gains in selecting embryos for desirable traits.
  3. Critics of genetic enhancement technologies should make fair comparisons with existing methods and consider the overall benefits.
Secretum Secretorum β€’ 505 implied HN points β€’ 14 Mar 23
  1. Ethical dilemmas arise when teaching and mentoring individuals with a history of heinous crimes like pedophilia.
  2. Taboos around discussing pedophilia can hinder conversations about related issues such as mentoring and societal norms.
  3. The genetic component of pedophilia and potential medical interventions raise complex ethical questions that society will inevitably need to address.
LIL Science β€’ 471 implied HN points β€’ 18 May 23
  1. Research has identified genetic variations that make people more likely to have severe COVID-19.
  2. The likely cause of acute deadly hepatitis in children has been identified as a combination of viruses and genetic predispositions.
  3. The origin of SARS-CoV-2 is still under investigation, with reports detailing activities in China preceding the pandemic.
Nothing Human is Alien β€’ 39 implied HN points β€’ 05 Feb 24
  1. The technology to select genetic traits in embryos is becoming more advanced and accessible, with possibilities ranging from preventing diseases to enhancing traits like intelligence and happiness.
  2. Genetic selection through technologies like Preimplantation Genetic Testing (PGT) raises ethical concerns due to its potential to create a two-tiered society and impact the essence of humanity.
  3. Although genetic selection technology poses risks, it also holds the promise of eradicating diseases, promoting happier individuals, and potentially enhancing cognitive abilities to unprecedented levels.