The hottest Nutrition Substack posts right now

And their main takeaways
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Top Health & Wellness Topics

Vitamin D and Dementia

Neuro Athletics • 13 implied HN points • 17 Jun 25
🏥 Health & Wellness Nutrition Mental health Aging Cognitive health Supplements
  1. Taking vitamin D can lower the risk of dementia by 40%, according to a study of over 12,000 adults. That's a big number for such a cheap supplement!
  2. Women benefit the most from vitamin D; those without cognitive issues can see up to a 56% reduction in risk. It's really important for brain health, especially in women.
  3. Vitamin D does a lot for the brain, like reducing inflammation and helping brain cells grow. It might be one of the best, simplest ways to protect your brain as you age.

A Few Big Ideas That Made My Life Better

Vonnik’s Newsletter • 39 implied HN points • 15 Oct 24
🏥 Health & Wellness Mental health Self-Improvement Nutrition Physical Fitness Mindfulness
  1. Taking care of your body improves your mood and thoughts. Simple actions like exercising or breathing deeply can boost your energy and change how you see challenges.
  2. Making small changes in your habits is much easier than trying to change everything at once. Starting with tiny steps, like doing one pushup, helps build lasting habits.
  3. Being mindful of distractions and focusing your attention are key to reaching your goals. Managing your environment and your thoughts can help you stay on track.

Is Hydrogen Sulfide the New Estrogen?

Harnessing the Power of Nutrients • 1098 implied HN points • 15 Jun 24
🏥 Health & Wellness Nutrition Hormones Research Metabolism
  1. Hydrogen sulfide, a gas with signaling roles, may have estrogenic effects in the body.
  2. High concentrations of hydrogen sulfide can have toxic effects, while lower concentrations are essential for placental function.
  3. Research suggests that hydrogen sulfide could mimic estrogen's effects, potentially leading to various health issues.

The Dose (January 3)

Your Local Epidemiologist • 1867 implied HN points • 03 Jan 25
🏥 Health & Wellness Public Health Vaccination Nutrition Disease Prevention Epidemiology
  1. Winter is here, and respiratory illnesses like flu, COVID, and RSV are on the rise across the country. It's important to stay aware as health services could get overwhelmed.
  2. The new COVID-19 vaccine is showing good results, especially for older adults, helping to reduce hospital visits significantly. Keeping up with vaccinations can strengthen your immunity.
  3. Some Costco eggs may be contaminated with salmonella, so it's best to check your fridge and avoid those eggs to keep your family safe.

What is the truth about alcohol consumption

Vinay Prasad's Observations and Thoughts • 235 implied HN points • 13 Jan 25
🏥 Health & Wellness Nutrition Mental health Public Health Lifestyle Substance Use
  1. Moderate alcohol consumption might not be as harmful as some studies suggest, but it's essential to consider various health impacts when deciding how much to drink.
  2. Understanding what and how much we drink can help manage health risks better. It's important to enjoy alcohol responsibly without overthinking it.
  3. More research is needed to understand the true effects of alcohol on health, and personal experiences and preferences should also play a role in drinking habits.
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CO2-curious

Experimental Fat Loss • 141 implied HN points • 20 Jan 25
🏥 Health & Wellness Nutrition Mental health Wellness Trends Chronic Conditions
  1. High CO2 levels can make people feel dizzy or stuffy, but this doesn’t always mean they will get headaches. Personal experiences with varying CO2 levels in different environments lead to different symptoms.
  2. The old homes might have better airflow compared to modern buildings, which could lead to fewer headache symptoms despite higher CO2 levels. The construction of a building can impact how we feel in relation to CO2 exposure.
  3. Making assumptions based on CO2 measurements alone can be misleading. It’s important to consider other factors or pollutants that may actually cause discomfort or headaches.

My Iron Deficiency Protocol

Harnessing the Power of Nutrients • 1078 implied HN points • 04 Jun 24
🏥 Health & Wellness Nutrition Supplements Hormones
  1. Iron deficiency can manifest in various symptoms beyond anemia, including low sex hormones, fatigue, and hair loss.
  2. Optimizing iron levels can have significant impacts on hormone balance, immunity, and overall well-being, especially during aging.
  3. The iron deficiency protocol includes guidance on foods, supplements, inflammation management, and genetic factors to consider.

Is THIS Behind Your Muscle Tension?

Harnessing the Power of Nutrients • 958 implied HN points • 11 Jun 24
🏥 Health & Wellness Fitness Nutrition Holistic health Supplementation
  1. S-sulfocysteine could be a hidden cause of muscle tension and related symptoms, especially between meals.
  2. Supplementing with 600-1200 micrograms of molybdenum may significantly reduce muscle tension levels, but individual needs and metabolic complexities should be considered.
  3. Optimal muscle tone regulation is key, influenced by neurotransmitters like glutamate, glycine, GABA, and taurine, with molybdenum showing impressive results in reducing muscle tension.

Why You Should Track Your Diet in Cronometer

Harnessing the Power of Nutrients • 1018 implied HN points • 28 May 24
🏥 Health & Wellness Nutrition Self-experimentation
  1. Tracking your diet in Cronometer helps you ensure you meet nutritional targets like protein, fat, carbs, vitamins, and minerals.
  2. Using Cronometer for self-experimentation provides insights by manipulating food components and controlling variables to observe changes.
  3. Cronometer offers precision in tracking, allowing for detailed analysis of nutritional intake which aids in making informed dietary adjustments.

YLE milestone, Red Dye #3, air quality in LA, raw cat food, and more on alcohol.

Your Local Epidemiologist • 1187 implied HN points • 17 Jan 25
🏥 Health & Wellness Public Health Nutrition Epidemiology Environmental health Policy
  1. The FDA has banned Red Dye No. 3 from food and drugs because it was linked to cancer in lab animals. Even though it's mostly gone already, some products in stores still have it.
  2. Air quality can be misleading after wildfires. Just because the air is rated as 'healthy' doesn't mean it's safe, as many harmful pollutants might still be present.
  3. Moderate drinking might not be as safe as we thought. Recent reports suggest that even one drink a day could increase health risks, especially if there are other health issues involved.

Obesity: Root Cause Analysis

Experimental Fat Loss • 268 implied HN points • 24 Dec 24
🏥 Health & Wellness Nutrition Obesity Diabetes Health Research
  1. Obesity and diabetes rates have soared in the last few decades, showing something has fundamentally changed in our lifestyle or diet since the 1800s.
  2. Understanding the mechanisms behind diet and health is important, but we also need to focus on finding practical solutions rather than just theoretical ones.
  3. Evaluating various diet ideas from personal experiences or small experiments can be more effective than relying solely on large studies, as many common narratives about health don't fully explain the issues we face today.

Menopause and Weight: There is No Code to Crack

The Vajenda • 5287 implied HN points • 29 May 23
🏥 Health & Wellness Menopause Weight management Nutrition Exercise
  1. There is no special code or secret for weight loss during menopause, despite what some predatory sources may claim.
  2. Hormone therapy does not aid in weight loss or boost metabolism during menopause.
  3. Menopause itself is not directly linked to weight gain, but weight changes tend to be influenced by factors like age and lifestyle choices.

Maybe THIS Is Why You're Hangry

Harnessing the Power of Nutrients • 1817 implied HN points • 19 Mar 24
🏥 Health & Wellness Nutrition Metabolism Genetics Research
  1. Feeling hangry might not always be due to low blood sugar, other factors like S-sulfocysteine levels in your urine could play a role in overstimulation symptoms.
  2. Elevated S-sulfocysteine, a neurostimulant, can result from breakdown of protein when hungry for glucose and may lead to various overstimulation symptoms like anxiety and muscle tension.
  3. Testing for S-sulfocysteine levels in urine should be more widely implemented to understand its potential impact on psychological traits and neuro-psychiatric diseases.

ExFatloss 2024: Year in Review

Experimental Fat Loss • 205 implied HN points • 30 Dec 24
🏥 Health & Wellness Weight Loss Nutrition Dieting
  1. In 2024, there were many experiments and personal weight changes, with weight fluctuating but often hovering around the lowest point in several years.
  2. Tools like the Omega Tracker and various calculators were created to help people understand their dietary impact and weight loss journey better.
  3. There are new goals for the future, focusing on sharing knowledge and enabling others to experiment with their diets rather than just personal progress.

50. Inspiration needs no boundaries!

Spyderdoc Newsletter • 19 implied HN points • 06 Jun 25
🏥 Health & Wellness Longevity Nutrition Mental health Travel
  1. Inspiration can come from anywhere, and it has no limits. It's important to embrace new ideas and experiences to grow.
  2. Preventive medicine is key to living a long and healthy life. Taking care of our health today helps us avoid problems in the future.
  3. Traveling broadens our horizons. Experiencing new cultures and places teaches us valuable lessons and ignites our curiosity.

The Mitochondrial Nutrient Missing From Every Supplement

Harnessing the Power of Nutrients • 2536 implied HN points • 30 Jan 24
🏥 Health & Wellness Nutrition Supplements Mitochondria Vitamins
  1. There's a key nutrient, MK-4, crucial for mitochondrial health that is often missing from many supplements.
  2. MK-4 and CoQ10 have similar structures and roles in the respiratory chain, but play distinct functions and cannot substitute each other.
  3. For optimal mitochondrial support, it's recommended to include MK-4 alongside CoQ10 in a ratio of around 1 microgram of MK-4 for every 1 milligram of CoQ10.

Iron Overload: Forget What You Thought You Knew

Harnessing the Power of Nutrients • 1817 implied HN points • 09 Mar 24
🏥 Health & Wellness Nutrition Genetics Diet Medical Research Health Risks
  1. Iron overload can lead to serious health issues like liver damage and heart problems, and may accelerate aging.
  2. Manganese overload is linked to symptoms like headaches and balance issues and can be a concern for those with genetic predispositions to iron overload.
  3. When managing iron overload, it's critical to limit dietary manganese intake, maintain a proper iron-to-manganese ratio, and be cautious about how blood donation affects manganese toxicity.

Post-rice OmegaQuant: 8% linoleic acid

Experimental Fat Loss • 162 implied HN points • 03 Jan 25
🏥 Health & Wellness Nutrition Dieting Health Testing Wellness Trends
  1. Eating very low-fat diets, like a rice diet, can deplete the body's linoleic acid faster. When you stop taking in certain fats, your body starts using fat stored in your tissues.
  2. The OmegaQuant Complete test can give a rough idea of linoleic acid levels, but it's not completely accurate. It's a useful tool, but results should be interpreted carefully due to various factors.
  3. Body fat levels and diet can greatly affect fatty acid profiles. If you're on a low-fat diet, your body might produce more of its own fats, which can influence test results.

174 | The Nitty-Gritty of Risk Assessments | Food Waste Follow-up |

The Rotten Apple • 52 implied HN points • 03 Feb 25
🍲 Food & Drink Food Safety Food Fraud Risk Assessment Food Waste Nutrition
  1. A food safety risk assessment helps determine how likely it is for something harmful in food to make you sick. This process looks at the chance of illness and how serious it could be.
  2. Recent cases showed that salad can lead to food poisoning if it gets contaminated. In one incident, a salad caused many airplane passengers to fall ill due to a toxin from bacteria.
  3. A huge amount of food is wasted globally, especially at home. Efforts and resources are being shared to help people reduce food waste effectively.

ex150-12 review: Holiday Edition

Experimental Fat Loss • 127 implied HN points • 10 Jan 25
🏥 Health & Wellness Nutrition Dieting Weight Loss Fitness Lifestyle
  1. Following a special diet led to a quick weight loss of about 4 pounds, but it might just be water weight from changes in food intake.
  2. During the holidays, more flexibility in eating was allowed, but it didn't seem to majorly affect overall weight loss.
  3. Future experiments with different diets, like one focused on honey, are planned to see how they compare with previous food plans.

Paid content: Packing the spring box

Wood From Eden • 240 implied HN points • 20 Dec 24
🍲 Food & Drink Gardening Sustainability Cooking Nutrition Seasonal
  1. Packing a spring box is an important task for preparing for the season. It involves organizing and storing supplies that will help with gardening and planting.
  2. Creating a rational vegetable garden can lead to better productivity and more enjoyable gardening experiences. Planning ahead and using resources wisely is key.
  3. Paid subscriptions can provide access to special content that dives deeper into gardening topics. This can help gardeners learn more and improve their skills.

Are Seed Oils Behind Your Oxalate Problem?

Harnessing the Power of Nutrients • 1777 implied HN points • 29 Feb 24
🏥 Health & Wellness Nutrition Detoxification Antioxidants Metabolism Genetics
  1. High oxalate levels might be due to seed oils leading to glyoxal production which is a major source of oxalate.
  2. Reducing consumption of seed oils in favor of tropical oils, olive oil, and grass-fed animal fats might help lower oxalate production.
  3. Nutrients like biotin, B12, and folate play roles in detoxifying oxalate, and checking for energetic bottlenecks through comprehensive screenings can help address oxalate issues.

The Problem With Coconut

Harnessing the Power of Nutrients • 1577 implied HN points • 11 Mar 24
🏥 Health & Wellness Nutrition Genetics Diet
  1. Not everyone's genes are compatible with a high coconut diet, especially if you have a predisposition to iron and manganese overload.
  2. Coconuts are rich in manganese, which can be harmful if you struggle with regulating manganese absorption.
  3. If you experience symptoms like headaches, irritability, or tremors while consuming a lot of coconut, you might want to consider reducing your intake.

How I Found My Health “Super Unlock” After 20 Years of Research and 20,000 Genes Tested

Harnessing the Power of Nutrients • 4034 implied HN points • 21 Sep 23
🏥 Health & Wellness Metabolism Diet Nutrition
  1. Each person has unique health unlocks that are specific to them and can be found through whole genome sequencing.
  2. Identifying rare metabolic disease genes through personalized testing can lead to targeted health improvements.
  3. Addressing individual genetic mutations related to energy metabolism can result in significant health benefits and improved overall wellness.

Seeing the Forest for the Trees

Your Local Epidemiologist • 1187 implied HN points • 10 Dec 24
🏥 Health & Wellness Nutrition Public Health Chronic Disease Physical activity Substance Use
  1. Eating well is really important for health. A better diet can help reduce the risk of diseases and save money on healthcare.
  2. Staying active helps improve overall health, but many people find it difficult due to challenges like unsafe neighborhoods or busy schedules. People need safe spaces and support to exercise.
  3. Reducing substance use, like smoking and excessive drinking, is crucial for health. Public health efforts have made progress, but more work is needed to keep improving.

How to (and not to) detox in the New Year

Your Local Epidemiologist • 850 implied HN points • 10 Jan 25
🏥 Health & Wellness Nutrition Detox Fitness Mental health Public Health
  1. A balanced diet with good nutrition helps your body detox naturally. Eating healthy foods supports your organs and keeps everything working well.
  2. Staying hydrated is important. Drinking enough water helps your kidneys and digestive system do their job of removing waste.
  3. Many trendy detox methods, like extreme diets or detox drinks, are not proven to work and can sometimes be harmful. It's better to focus on healthy habits like regular exercise and reducing alcohol.

Reader Question - My Doctor Claims He Can "Jump Start" Weight Loss?

Weight and Healthcare • 878 implied HN points • 04 May 24
🏥 Health & Wellness Weight Loss Nutrition Medical Ethics Body positivity Health Research
  1. Behavior-based weight loss interventions usually fail to produce significant, long-term weight loss for most people.
  2. The idea of 'jump starting' weight loss with extreme food/caloric restrictions is generally ill-advised as it can trigger famine responses in the body, making it a weight-gaining machine.
  3. Promoting or selling products like liquid diets by medical professionals is not legally prohibited, but the evidence does not support the effectiveness of 'kick starting' weight loss as a long-term solution.

Thiamin Supplements: Not For Everyone

Harnessing the Power of Nutrients • 1697 implied HN points • 19 Feb 24
🏥 Health & Wellness Nutrition Supplementation Metabolism Mitochondria Toxicity
  1. Thiamin is crucial for various functions like stable blood glucose, calmness, tissue health, detoxification, and athletic performance.
  2. Thiamin deficiency can lead to issues such as mitochondrial dysfunction, nerve problems, and eyesight deterioration.
  3. Excessive thiamin supplementation may cause adverse effects and stress on metabolic pathways, so it's important to be mindful of when to supplement thiamin and when to stop.

The Longevity Cult

We're Gonna Get Those Bastards • 6 implied HN points • 07 Jun 25
🏥 Health & Wellness Longevity Nutrition Exercise Mental health Lifestyle
  1. Some people are so obsessed with living longer that they forget to really enjoy life. It's important to balance health and happiness.
  2. Living a long life doesn't mean much if it’s boring or unproductive. Focus on doing what makes you happy instead of just extending your years.
  3. Making time for your passions and dreams is crucial. Exercising and focusing on longevity is good, but don't lose sight of what truly matters to you.

CoQ10 Deficiency Is Sulfur Toxicity

Harnessing the Power of Nutrients • 1358 implied HN points • 12 Mar 24
🏥 Health & Wellness Nutrition Toxicity Supplementation Metabolism Genetics
  1. CoQ10 deficiency is linked to sulfur toxicity, impacting various bodily functions and potentially causing issues like anxiety after eating meat or taurine consumption.
  2. Hydrogen sulfide, a necessary gasotransmitter, can turn toxic at high concentrations, affecting the body's ability to convert food energy to ATP.
  3. Taurine can help counteract the effects of sulfur toxicity by suppressing the trans-sulfuration pathway, which can prevent the overproduction of hydrogen sulfide and sulfite.

Is Vitamin C Destroying Your Mitochondria?

Harnessing the Power of Nutrients • 1617 implied HN points • 17 Feb 24
🏥 Health & Wellness Nutrition Supplements Mitochondria Oxidative stress Metabolism
  1. High doses of Vitamin C can inhibit CoQ10 synthesis and decrease copper status, affecting mitochondrial function.
  2. Excessive Vitamin C intake can lead to the generation of oxalate, a mitochondrial toxin, causing potential mitochondrial damage.
  3. While high doses of Vitamin C can have benefits in specific cases, for general use, it's safer to stick to doses from a Vitamin C-rich diet.

Hey, Aren't We Supposed to Be Hibernating Right Now?

OK Doomer • 136 implied HN points • 02 Jan 25
🏥 Health & Wellness Mental health Physical health Nutrition Lifestyle Wellness
  1. Motivational marketing is coming, trying to get us to work harder and spend money. Be ready for advertisements about fitness, side hustles, and investments.
  2. Many people experience seasonal affective disorder during winter, making them crave comfort food and feel less motivated. This is just a natural response to the cold months.
  3. Hibernation is a survival tool that has helped some mammals endure tough conditions. It's not a disorder but an evolutionary advantage for some species.

A Simple DIY Home Test for Molybdenum Deficiency

Harnessing the Power of Nutrients • 1437 implied HN points • 25 Feb 24
🏥 Health & Wellness Nutrition DIY Supplements Detoxification Testing
  1. Molybdenum is crucial for converting toxic sulfite to useful sulfate in the body. Deficiency can lead to various health issues like anxiety, sleep problems, and more.
  2. Lab testing for molybdenum status is often inadequate, with tests focused on ruling out toxicity rather than assessing deficiency.
  3. A simple DIY home test for molybdenum status can be done with minimal equipment, a molybdenum supplement, and a few days of data collection, providing a potentially more practical approach to monitoring levels.